1,601 Result(s)
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**huan Chen
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Article
Open AccessDissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters
Blood pressure or flow measurements have been associated with vascular health and cognitive function. We proposed that energetic hemodynamic parameters may provide a more nuanced understanding and stronger cor...
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Article
A novel nomogram to predict glucocorticoid response in thyroid-associated ophthalmopathy: findings from a pilot study
Aimed to create a nomogram using clinical and eye-specific metrics to predict the efficacy of intravenous glucocorticoid (IVGC) therapy in patients with active and moderate-to-severe Thyroid-Associated Ophthal...
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Article
GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma
Despite significantly improved clinical outcomes in EGFR-mutant lung adenocarcinoma, all patients develop acquired resistance and malignancy on the treatment of EGFR tyrosine kinase inhibitors (EGFR-TKIs). Und...
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Analysis of Heavy Metal Characteristics and Health Risk Assessment of Dried Fish Marketed in Guangzhou, China
This study investigated heavy metal contamination in dried fish sold in Guangzhou, China, and evaluated the resultant non-carcinogenic and carcinogenic health risks. Dried fish samples were purchased from Baiy...
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Open AccessClinical application of a GPU-accelerated monte carlo dose verification for cyberknife M6 with Iris collimator
To apply an independent GPU-accelerated Monte Carlo (MC) dose verification for CyberKnife M6 with Iris collimator and evaluate the dose calculation accuracy of RayTracing (TPS-RT) algorithm and Monte Carlo (TP...
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Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Efficiency of PGK1 proteins delivered to the brain via a liposomal system through intranasal route administration for the treatment of spinocerebellar ataxia type 3
A patient-friendly and efficient treatment method for patients with spinocerebellar ataxia type 3 (SCA3) was provided through a nose-to-brain liposomal system. Initially, PGK1 was overexpressed in HEK 293-84Q-...
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Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Article
A differential privacy-preserving federated learning scheme with predictive maintenance of wind turbines based on deep learning for feature compression and anomaly detection with state assessment
The transport and supply of traditional energy have been greatly affected, which has attracted the attention of countries worldwide and has become an urgent issue. Limited by its own traditional energy shortag...
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Article
Ceramicized NASICON-based solid-state electrolytes for lithium metal batteries
In this work, we have developed ceramicized hybrid solid state electrolytes (SSEs), which consisted of poly (vinylidene fluoride-hexafluoro propylene) (PVDF-HFP), lithium bis (trifluoromethanesulfonyl)imide (L...
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Article
Copper pruning improves root morphology and structure as well as growth of container-grown Ligustrum lucidum seedings
It is unclear how high concentrations of copper affect the structure and function of roots in the process of controlling root entanglement in containers although copper pruning technology has been widely appli...
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Article
Spatiotemporal analysis of contrast-enhanced ultrasound for differentiating between malignant and benign breast lesions
The aim of this study was to apply spatiotemporal analysis of contrast-enhanced ultrasound (CEUS) loops to quantify the enhancement heterogeneity for improving the differentiation between benign and malignant ...
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Article
Exploring synergistic decoupling of haze pollution and carbon emissions in emerging economies: fresh evidence from China
In the face of global warming, energy depletion, and air pollution, controlling greenhouse gas and air pollutant emissions has become an urgent task for an emerging economy. Therefore, this study investigates ...
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Article
Strategic Licensing Model Choice with Network Effects in a Dynamic Duopoly
Network effects encourage the innovative firms to expand their market size by licensing the technology to the third-party manufacturers who provide substitutable but incompatible products in a duopoly. Moreove...
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Open AccessCorrection: A retrospective analysis of the incidence and risk factors of perioperative urinary tract infections after total hysterectomy
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Article
Open AccessClinical efficacy and identification of factors confer resistance to afatinib (tyrosine kinase inhibitor) in EGFR-overexpressing esophageal squamous cell carcinoma
Epidermal growth factor receptor (EGFR) is reportedly overexpressed in most esophageal squamous cell carcinoma (ESCC) patients, but anti-EGFR treatments offer limited survival benefits. Our preclinical data sh...
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Article
Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
The obesity paradox has been reported among older adults. However, whether the favorable effect of obesity is dependent on metabolic status remains largely unknown. We aimed to explore the association of metab...
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Article
Open AccessProduction of constrained L-cyclo-tetrapeptides by epimerization-resistant direct aminolysis
The synthesis of constrained 12-membered rings is notably difficult. The main challenges result from constraints during the linear peptide cyclization. Attempts to overcome constraints through excessive activa...
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Article
Reuse of construction and demolition waste (CDW) fines as plant-growing substrate
The reuse of construction and demolition waste (CDW) is of great significance for the reasonable treatment of urban waste and the protection of soil. CDW fines less than 10 mm in size were used to explore the ...
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Open AccessExploring new frontiers: a rare case of catheter ablation for persistent atrial fibrillation in a patient with cor triatriatum sinister guided by intracardiac echocardiography
Cor triatriatum sinister (CTS) is an uncommon congenital cardiac anomaly. Atrial fibrillation (AF) is commonly the initial symptom in patients with CTS, occurring in approximately 32% of the cases. The complex...
