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1,114 Result(s)
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Article
Correction to: Supporting Students’ Use of Ecological Concepts in Field‑Based Modeling of Ecological Phenomena
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Article
Deletion of IRC19 Causes Defects in DNA Double-Strand Break Repair Pathways in Saccharomyces cerevisiae
DNA double-strand break (DSB) repair is a fundamental cellular process crucial for maintaining genome stability, with homologous recombination and non-homologous end joining as the primary mechanisms, and vari...
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Article
Effect of air-frying on formation and correlations of polycyclic aromatic hydrocarbons, acrylamide, and heterocyclic aromatic amines in foods and risk assessment
The levels of acrylamide (AA), four polycyclic aromatic hydrocarbons (PAH4), and heterocyclic aromatic amines (HAAs) in 184 air-fried agricultural, fishery, and animal products were measured using GC–MS and UP...
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Open AccessEffect of Pravastatin on Kidney Function in Patients with Dyslipidemia and Type 2 Diabetes Mellitus: A Multicenter Prospective Observational Study
Several studies have reported that pravastatin can mitigate the progression of kidney disease, but limited evidence exists regarding its effects on kidney function in Asian patients. This multicenter prospecti...
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Open AccessAir pollution and survival in patients with malignant mesothelioma and asbestos-related lung cancer: a follow-up study of 1591 patients in South Korea
Despite significant advancements in treatments such as surgery, radiotherapy, and chemotherapy, the survival rate for patients with asbestos-related cancers remains low. Numerous studies have provided evidence...
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Open AccessProteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis
Avascular necrosis (AVN) is a medical condition characterized by the destruction of bone tissue due to a diminished blood supply. When the rate of tissue destruction surpasses the rate of regeneration, effecti...
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Effect of modification methods on the physical properties and immunomodulatory activity of particulate β-glucan
β-Glucan is an immunoenhancing agent whose biological activities are linked to molecular structure. On that basis, the polysaccharide can be physiochemically modified to produce valuable functional materials. ...
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Article
Revisiting prognostic factors of gliomatosis cerebri in adult-type diffuse gliomas
There is lack of comprehensive analysis evaluating the impact of clinical, molecular, imaging, and surgical data on survival of patients with gliomatosis cerebri (GC). This study aimed to investigate prognosti...
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Open AccessMachine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores
We construct non-linear machine learning (ML) prediction models for systolic and diastolic blood pressure (SBP, DBP) using demographic and clinical variables and polygenic risk scores (PRSs). We developed a tw...
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Open AccessDRG2 is required for surface localization of PD-L1 and the efficacy of anti-PD-1 therapy
More than half of tumor patients with high PD-L1 expression do not respond to anti-PD-1/PD-L1 therapy, and the underlying mechanisms are yet to be clarified. Here we show that developmentally regulated GTP-bin...
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Article
Star-shaped PEDOT:PSS conductive polymers with reduced graphene oxide for high performance supercapacitor
Three-armed poly(styrene sulfonate) derivatives (PSS-T) was synthesized by atom transfer radical polymerization (ATRP) and used as dopants for the preparation of star-shaped PEDOT:PSS-T composites. From their ...
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Article
Open AccessRespiratory pathogen and clinical features of hospitalized patients in acute exacerbation of chronic obstructive pulmonary disease after COVID 19 pandemic
Respiratory infections are common causes of acute exacerbation of chronic obstructive lung disease (AECOPD). We explored whether the pathogens causing AECOPD and clinical features changed from before to after ...
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Article
MRI radiomics may predict early tumor recurrence in patients with sinonasal squamous cell carcinoma
Sinonasal squamous cell carcinoma (SCC) follows a poor prognosis with high tendency for local recurrence. We aimed to evaluate whether MRI radiomics can predict early local failure in sinonasal SCC.
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Cerebrospinal fluid flow artifact reduction with deep learning to optimize the evaluation of spinal canal stenosis on spine MRI
The aim of study was to employ the Cycle Generative Adversarial Network (CycleGAN) deep learning model to diminish the cerebrospinal fluid (CSF) flow artifacts in cervical spine MRI. We also evaluate the agree...
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Open AccessSystematic determination of the optimized Zr content of Ba(ZrxTi1-x)O3 with high dielectric constant at room temperature for high-voltage system application
In this study, by replacing the B-site element in BaTiO3, a ferroelectric material, with an element with a larger ionic radius, a ferroelectric material with high permittivity at room temperature was synthesized....
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Identification and characterization of Acinetobacter nosocomialis BfmRS, two-component regulatory system, essential for biofilm development
Biofilm development by bacteria is considered to be an essential stage in the bacterial infection. Acinetobacter nosocomialis is an important nosocomial pathogen causing a variety of human infections. However, ch...
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Article
Anterior mediastinal nodular lesion segmentation from chest computed tomography imaging using UNet based neural network with attention mechanisms
Automated detection of anterior mediastinal nodular lesions (AMLs) has significance for clinical usage as it is challenging for radiologists to accurately identify AMLs from chest computed tomography (CT) imag...
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Open AccessAdvances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges
Mass spectrometry (MS)-based intact mass analysis and structural characterization of biotherapeutic proteins such as monoclonal antibodies (mAbs) are a crucial characterization approach from upstream drug deve...
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Open AccessInsights into plant regeneration: cellular pathways and DNA methylation dynamics
Plants, known for their immobility, employ various mechanisms against stress and damage. A prominent feature is the formation of callus tissue—a cellular growth phenomenon that remains insufficiently explored,...
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Open AccessSARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids
SARS-CoV-2 provokes devastating tissue damage by cytokine release syndrome and leads to multi-organ failure. Modeling the process of immune cell activation and subsequent tissue damage is a significant task. O...