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Article
Open AccessCamrelizumab-based induction chemoimmunotherapy in locally advanced stage hypopharyngeal carcinoma: phase II clinical trial
This phase II trial aimed to determine the efficacy and safety of induction chemoimmunotherapy of camrelizumab plus modified TPF in locally advanced hypopharyngeal squamous cell carcinoma (LA HSCC) (NCT0415669...
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Article
Open AccessPopulation genomics and epigenomics of Spirodela polyrhiza provide insights into the evolution of facultative asexuality
Many plants are facultatively asexual, balancing short-term benefits with long-term costs of asexuality. During range expansion, natural selection likely influences the genetic controls of asexuality in these ...
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Article
Mechanical Response and Failure Mechanism of AFRP-repaired Corroded CHS Tubes Under Axial Compression
Corrosion-induced defects, extensive and unavoidable in marine structures, pose significant threats to structural integrity and safety. This study aims to assess mechanical response and investigate the failure...
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Article
Open AccessExtend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project
Accurate indel calling plays an important role in precision medicine. A benchmarking indel set is essential for thoroughly evaluating the indel calling performance of bioinformatics pipelines. A reference samp...
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Article
Theoretical study of bearing capacity calculation model for multi-segment confined concrete arch and design method in underground engineering
With the continuous development of underground engineering to the deep, complex geologic conditions such as high stress, extremely soft rock and fault fracture zone usually occurred in the construction process...
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Article
Open AccessA high-quality genome assembly of the waterlily aphid Rhopalosiphum nymphaeae
Waterlily aphid, Rhopalosiphum nymphaeae (Linnaeus), is a host-alternating aphid known to feed on both terrestrial and aquatic hosts. It causes damage through direct herbivory and acting as a vector for plant vir...
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Article
Experimental and Numerical Study on the Bearing Behaviour of Confined Concrete Arch for a Traffic Tunnel
The control of surrounding rock is a challenge faced during large-section tunnel construction, resulting in insufficient strength of the traditional support. Confined concrete arches with high strength and rig...
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Article
Efficacy and safety of Huachansu combined with adjuvant chemotherapy in resected colorectal cancer patients: a prospective, open-label, randomized phase II study
Although some studies in China have suggested Huachansu (HCS) combined with chemotherapy is effective in the treatment of various cancers, there are few studies on colorectal cancer (CRC), especially in postop...
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Article
Length minima for an infinite family of filling closed curves on a one-holed torus
We explicitly find the minima as well as the minimum points of the geodesic length functions for the family of filling (hence non-simple) closed curves, ...
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Article
Minimal Euler characteristics of 4-manifolds with 3-manifold groups
Let π = π1(M) for a compact 3-manifold M, and χ4, p and q* be the invariants of Hausmann and Weinberger (1985), Kotschick (1994) and Hillman (2002), respectively. For a certain class of compact 3-manifolds M, inc...
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Article
The value of plasma presepsin as a diagnostic and prognostic biomarker for sepsis in Southern China
Presepsin is a soluble CD14 subtype that has been considered as a novel marker for patients with sepsis. This study explored the clinical value of presepsin for sepsis in Southern China, and further establishe...
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Article
Distributions of points on non-extensible closed curves in \({\mathbb {R}}^3\) realizing maximum energies
Let \(G_n\) G n
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Article
Neutron moderator structure improvement of a PGNAA online analysis system based on DT neutron generator
The neutron moderator structure of a prompt gamma-ray neutron activation analysis (PGNAA) system based on a deuterium–tritium (DT) neutron generator was re-optimized. In this study, a 1 cm lead combined with a...
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Article
Recyclable thermo-insulating panels made by reversible gelling of dispersed silica aerogel microparticles
Hydrophobic silica aerogel composite materials are considered as one of the most promising thermal insulation materials in energy-saving buildings. With the increasing negative effect on the environment of con...
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Article
Rapid detection method of Skeletonema pseudocostatum and preparation of test strip
In eutrophic waters, harmful algal blooms (HAB) are particularly prone to occur, which will affect the ecological environment and public health and safety. How to quickly detect and monitor marine microalgae i...
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Article
Open AccessRice MPK17 Plays a Negative Role in the Xa21-Mediated Resistance Against Xanthomonas oryzae pv. oryzae
Rice bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most serious diseases affecting rice production worldwide. Xa21 was the first disease resistance gene cloned in rice, which enco...
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Article
The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition
The transition from acute kidney injury (AKI) to chronic kidney disease (CKD) is extremely complex. Incomplete renal tubule repair, inflammation, and endoplasmic reticulum (ER) stress all play major roles. AKI...
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Article
The rapid induction of OsPR1A protein is crucial in Xa21-mediated rice bacterial blight resistance
Rice XA21 is an immune receptor kinase that confers broad-spectrum resistance against Xanthomonas oryzae pv. oryzae (Xoo). Pathogenesis-related (PR) proteins are located downstream of the plant immune system and ...
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Article
The Minimal Dimension of a Sphere with an Equivariant Embedding of the Bouquet of g Circles is \(2g-1\)
To embed the bouquet of g circles \(B_g\) B g ...
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Article
Comparison of the characterization of allergenic protein 3 (Pla a3) released from Platanus pollen grains collected in Shanghai during the spring of 2019 and 2020
Due to the COVID-19 pandemic in early 2020, large-scale industrial production has been stagnant and reduced, the urban air quality has been greatly improved. It provided an excellent opportunity to explore the...
