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  1. Article

    Open Access

    Diabetic kidney disease screening status and related factors: a cross-sectional study of patients with type 2 diabetes in six provinces in China

    To understand the awareness and practice of diabetic kidney disease (DKD) or nephropathy screening among community-based patients with type 2 diabetes in six provinces and cities in China, and to analyse the r...

    Zhang **a, Xuechun Luo, Yanzhi Wang, Tingling Xu in BMC Health Services Research (2024)

  2. No Access

    Article

    Adhesion molecule–targeted magnetic particle imaging nanoprobe for visualization of inflammation in acute lung injury

    Uncontrolled intra-alveolar inflammation is a central pathogenic feature, and its severity translates into a valid prognostic indicator of acute lung injury (ALI). Unfortunately, current clinical imaging appro...

    Pengli Gao, Yu Liu, **aoli Wang, **n Feng in European Journal of Nuclear Medicine and M… (2024)

  3. Article

    Open Access

    Cough flows as a criterion for decannulation of autonomously breathing patients with tracheostomy tubes

    Adequate cough or exsufflation flow can indicate an option for safe tracheostomy decannulation to noninvasive management. Cough peak flow via the upper airways with the tube capped is an outcome predictor for ...

    **gyi Ge, Guangyu Niu, Qing Li, Yi Li, Bo Yang, Haiming Guo in Respiratory Research (2024)

  4. Article

    Open Access

    ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism

    ABCA7 loss-of-function variants are associated with increased risk of Alzheimer’s disease (AD). Using ABCA7 knockout human iPSC models generated with CRISPR/Cas9, we investigated the impacts of ABCA7 deficiency o...

    Keiji Kawatani, Marie-Louise Holm, Skylar C. Starling in Molecular Psychiatry (2024)

  5. No Access

    Article

    Association of energy delivery with short-term survival in mechanically ventilated critically ill adult patients: a secondary analysis of the NEED trial

    The optimal energy delivery for mechanically ventilated patients is controversial, particularly during the first week of ICU admission. This study aimed to investigate the association between different caloric...

    Lanting Wang, Yi Long, Zixiong Zhang, Jiajia Lin in European Journal of Clinical Nutrition (2024)

  6. Article

    Open Access

    Expression and prognosis analysis of TBX2 subfamily in human lung carcinoma

    Lung cancer has a high morbidity and mortality rate of all cancers worldwide. Therefore, there is an urgent need for reliable cancer markers for diagnosis and prognosis of patients with lung cancer.

    Rui Mi, Qiubo Wang, Qingyang Liu, Fengying Jiang, Yuan Ji in Discover Oncology (2024)

  7. Article

    Open Access

    Long noncoding RNA XIST promotes cell proliferation and migration in diabetic foot ulcers through the miR-126-3p/EGFR axis

    The prevalence of diabetic foot ulcers (DFUs) has caused serious harm to human health. To date, a highly effective treatment is lacking. Long noncoding RNA X-inactive specific transcript (lncRNA XIST) has been...

    Wangbing Hong, Zhenfang **ong, **n Wang, **ncheng Liao in Diabetology & Metabolic Syndrome (2024)

  8. Article

    Open Access

    Prolonged vs intermittent intravenous infusion of β-lactam antibiotics for patients with sepsis: a systematic review of randomized clinical trials with meta-analysis and trial sequential analysis

    The prolonged β-lactam antibiotics infusion has been an attractive strategy in severe infections, because it provides a more stable free drug concentration and a longer duration of free drug concentration abov...

    **aoming Li, Yi Long, Guixin Wu, Rui Li, Mingming Zhou in Annals of Intensive Care (2023)

  9. No Access

    Article

    Diagnostic value of alkaline phosphatase and bone-specific alkaline phosphatase for metastases in breast cancer: a systematic review and meta-analysis

    Numerous studies had reported the diagnostic value of alkaline phosphatase (ALP) and its bone-specific isoforms (BAP) in the metastases of breast cancer (BC). The purpose of this meta-analysis was to summarize...

    Chengying Jiang, Fangke Hu, Jiazhen Li in Breast Cancer Research and Treatment (2023)

  10. Article

    Open Access

    Clinical outcomes of frozen–thawed blastocysts from zygotes with no or one pronucleus for in vitro fertilization and intracytoplasmic sperm injection cycles

    To investigate the clinical outcomes of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles using frozen–thawed blastocyst transfers derived from zygotes with no (0PN) or one pronuc...

    **aomei Tong, Jiamin **, Yamei Xue, Lu Fang in Archives of Gynecology and Obstetrics (2023)

  11. Article

    Primary assessment of the diversity of Omicron sublineages and the epidemiologic features of autumn/winter 2022 COVID-19 wave in Chinese mainland

    With the recent ongoing autumn/winter 2022 COVID-19 wave and the adjustment of public health control measures, there have been widespread SARS-CoV-2 infections in Chinese mainland. Here we have analyzed 369 vi...

    Gang Lu, Yun Ling, Minghao Jiang, Yun Tan, Dong Wei, Lu Jiang in Frontiers of Medicine (2023)

  12. No Access

    Article

    Minimally invasive management of concomitant gallstones and common bile duct stones: an updated network meta-analysis of randomized controlled trials

    To update a 2018 meta-analysis on the comparative efficacy and safety of four surgical techniques in patients with concomitant gallstones and common bile duct (CBD) stones.

    Jisheng Zhu, Guiyan Wang, Bin **e, Zhengying Jiang, Weidong **ao in Surgical Endoscopy (2023)

  13. Article

    Open Access

    Chest physiotherapy guided by electrical impedance tomography in high-dependency unit patients with pulmonary diseases: an introduction of methodology and feasibility

    Qing Li, Yi Li, Guangyu Niu, Mingna Li, Jia Deng, Knut Möller in Critical Care (2023)

  14. No Access

    Article

    Comparison of oncologic outcomes between pancreaticoduodenectomy and total pancreatectomy for pancreatic adenocarcinoma

    Pancreatoduodenectomy (PD) and total pancreatectomy (TP) are two surgical methods to treat patients with pancreatic head adenocarcinoma (PHAC). However, the oncologic outcomes of TP for PHAC remain controversi...

    Jisheng Zhu, Zhengying Jiang, Bin **e, Chengchao Fu, Weidong **ao in Surgical Endoscopy (2023)

  15. Article

    Open Access

    The prevalence and management of chronic pain in the Chinese population: findings from the China Pain Health Index (2020)

    Chronic pain is a common disease; about 20% of people worldwide suffer from it. While compared with the research on the prevalence and management of chronic pain in developed countries, there is a relative lac...

    Yingying Jiang, Tingling Xu, Fan Mao, Yu Miao, Botao Liu in Population Health Metrics (2022)

  16. No Access

    Article

    Hypoxic Hepatocellular Carcinoma Cells Acquire Arsenic Trioxide Resistance by Upregulating HIF-1α Expression

    Although arsenic trioxide (ATO) is used in the treatment of advanced hepatocellular carcinoma (HCC) in clinical trials, it is not satisfactory in terms of improving HCC patients’ overall survival. Intratumoral...

    Yaoting Chen, Huiqing Li, Dong Chen, **ongying Jiang in Digestive Diseases and Sciences (2022)

  17. Article

    Open Access

    Tracheostomy decannulation protocol in patients with prolonged tracheostomy referred to a rehabilitation hospital: a prospective cohort study

    The aim of the study was to assess the feasibility of a standardized tracheostomy decannulation protocol in patients with prolonged tracheostomy referred to a rehabilitation hospital.

    Ting Zhou, Jianjun Wang, Chenxi Zhang, Bin Zhang, Haiming Guo in Journal of Intensive Care (2022)

  18. Article

    Open Access

    A novel CREB5/TOP1MT axis confers cisplatin resistance through inhibiting mitochondrial apoptosis in head and neck squamous cell carcinoma

    Cisplatin resistance is one of the main causes of treatment failure and death in head and neck squamous cell carcinoma (HNSCC). A more comprehensive understanding of the cisplatin resistance mechanism and the ...

    Tong Tong, **ng Qin, Yingying Jiang, Haiyan Guo, **aoning Wang, Yan Li in BMC Medicine (2022)

  19. Article

    Abnormal Pulmonary Function in Early Parkinson’s Disease: A Preliminary Prospective Observational Study

    Early Parkinson’s disease (PD) may cause respiratory dysfunction; however the findings vary among studies. The aim of the preliminary prospective observational study was to explore the deterioration of pulmona...

    Chenxi Zhang, Jia Deng, Yi Li, Guangyu Niu, Mingna Li, Bin Zhang, Jianjun Wang in Lung (2022)

  20. Article

    Open Access

    Echocardiographic characteristics of PRKAG2 syndrome: a research using three-dimensional speckle tracking echocardiography compared with sarcomeric hypertrophic cardiomyopathy

    PRKAG2 syndrome is a rare disease characterized as left ventricular hypertrophy (LVH), ventricular preexcitation syndrome, and sudden cardiac death. Its natural course, treatment, and prognosis were significan...

    Lu Tang, Xuejie Li, Nianwei Zhou, Yingying Jiang, Cuizhen Pan in Cardiovascular Ultrasound (2022)

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