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    Article

    PD-L1 Expression Is Increased in LPS-Induced Acute Respiratory Distress Syndrome by PI3K-AKT-Egr-1/C/EBPδ Signaling Pathway

    The role of programmed death ligand 1 (PD-L1) has been extensively investigated in adaptive immune system. However, increasing data show that innate immune responses are also affected by the immune checkpoint...

    Chunguang Yan, **g Chen, Botao Wang, **gya Wang, Ming Luo, **gru Tong in Inflammation (2024)

  2. Article

    Open Access

    B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

    Modulation of T-cell responses has played a key role in treating cancers and autoimmune diseases. Therefore, understanding how different receptors on T cells impact functional outcomes is crucial. The influenc...

    Sadiye Amcaoglu Rieder, **gya Wang, Natalie White in Cellular & Molecular Immunology (2021)

  3. Article

    Open Access

    Circular RNA hsa_circ_0006401 promotes proliferation and metastasis in colorectal carcinoma

    Dysregulation of circular RNA (circRNA) expression is involved in the progression of cancer. Here, we aimed to study the potential function of hsa_circ_0006401 in colorectal cancer (CRC). CircRNA hsa_circ_0006...

    Chen**g Zhang, **aolu Zhou, **aoge Geng, Yu Zhang, **gya Wang in Cell Death & Disease (2021)

  4. Article

    Author Correction: c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Jochem H. Bernink, Yoichiro Ohne, Marcel B. M. Teunissen, **gya Wang in Nature Immunology (2020)

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    Article

    c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

    Here we identify a group 2 innate lymphoid cell (ILC2) subpopulation that can convert into interleukin-17 (IL-17)-producing NKp44 ILC3-like cells. c-Kit and CCR6 define this ILC2 subpopulation that exhibits ILC3...

    Jochem H. Bernink, Yoichiro Ohne, Marcel B. M. Teunissen, **gya Wang in Nature Immunology (2019)

  6. Article

    Open Access

    Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

    Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects. However, the underlying mechanisms remain el...

    Haitao Pan, Yujie Wang, Kun Na, Ying Wang, Lu Wang, Zhenhao Li in Cell Death & Disease (2019)

  7. Article

    Open Access

    Dendritic cells inhibit myeloid-derived suppressor cells infiltration and function in mouse B16 melanoma microenvironment

    Siyuan **a, Jun Wei, **gya Wang, Liqing Zhao in Journal for ImmunoTherapy of Cancer (2013)