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Article
Open AccessThe dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma
Although Bruton’s tyrosine kinase (BTK) inhibitors (BTKi) have significantly improved patient prognosis, mantle cell lymphoma (MCL) is still considered incurable due to primary and acquired resistance. We have...
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Article
Genome-wide association study and genomic selection of spike-related traits in bread wheat
Identification of 337 stable MTAs for wheat spike-related traits improved model accuracy, and favorable alleles of MTA259 and MTA64 increased grain weight and yield per plant.
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Article
Open AccessHealthcare workers perceptions of patient safety culture in selected Ghanaian regional hospitals: a qualitative study
Patient safety culture is an integral part of healthcare delivery both in Ghana and globally. Therefore, understanding how frontline health workers perceive patient safety culture and the factors that influenc...
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Article
Endoplasmic reticulum stress-induced NLRP3 inflammasome activation as a novel mechanism of polystyrene microplastics (PS-MPs)-induced pulmonary inflammation in chickens
Microplastics (MPs) have attracted growing attention worldwide as an increasingly prevalent environmental pollutant. In addition, chicken meat is currently the most widely consumed kind of poultry in the globa...
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Article
Open AccessThe performance of a deep learning system in assisting junior ophthalmologists in diagnosing 13 major fundus diseases: a prospective multi-center clinical trial
Artificial intelligence (AI)-based diagnostic systems have been reported to improve fundus disease screening in previous studies. This multicenter prospective self-controlled clinical trial aims to evaluate th...
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Chapter
C&D Waste Recycling and Management: Chinese Practices
China produced a large amount of construction and demolition (C&D) waste. Currently, most C&D waste in China is disposed of in landfills, which contradicts the core principles of circular economy, leading to a...
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Article
A strain of Vibrio alginolyticus isolated from Azumapecten farreri and its pathogenic mechanism using CRISPR-Cas9 technology
Scallops have become an important aquaculture species in China because they contain high-quality protein, and scallops are important health food that combines multiple effects and high economic benefits. Howev...
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Article
Open AccessCorrection: The need for digital health education among next-generation health workers in China: a cross-sectional survey on digital health education
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Article
Open AccessThe need for digital health education among next-generation health workers in China: a cross-sectional survey on digital health education
Digital health is important for sustainable health systems and universal health coverage. Since the outbreak of COVID-19, many countries, including China, have promoted the introduction of digital health in th...
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Article
Large-scale utilization of desulfurization ash and fly ash for unfired production of high-strength road-base stones
This paper utilizes desulfurization ash (DA), fly ash (FA) and ordinary Portland cement (OPC) to prepare unfired high-strength road-base stones by static pressure forming. The compressive strength after 28 day...
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Chapter and Conference Paper
Analysing Impacts of Landfill Charge on Recycling Rate Based on a System Dynamics System Model
In China, construction and demolition (C&D) waste is one of the largest waste streams. Majority of the waste is improperly managed and disposed in dum** sites. Therefore, there is a pressing need to properly...
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Article
Exploring the challenges in the development of retirement village homes through Public-Private Partnerships
The trend in population ageing has promoted a rapid growth in retirement village industry. However, a significant capital investment is required for develo** retirement villages. Applying the concept of publ...
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Article
Open AccessComprehensive bibliometric and visualized analysis of research on fecal microbial transplantation published from 2000 to 2021
Fecal microbial transplantation has emerged in recent years as a method of treating disease by rebuilding the intestinal flora. However, few bibliometric analyses have systematically studied this area of resea...
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Article
Fractalkine deficiency attenuates LPS-induced acute kidney injury and podocyte apoptosis by targeting the PI3K/Akt signal pathway
Podocyte injury is a major biomarker of primary glomerular disease, which leads to massive proteinuria and kidney failure. The increased production of the chemokine, fractalkine (FKN, CX3CL1), is a hallmark of...
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Article
The brassinosteroid biosynthesis gene TaD11-2A controls grain size and its elite haplotype improves wheat grain yields
TaD11-2A affects grain size and root length and its natural variations are associated with significant differences in yield-related traits in wheat.
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Article
Knowledge transfer learning from multiple user activities to improve personalized recommendation
Representation learning has attracted growing attention in recommendation system. In addition, deep learning has been adopted to build a representation generator based on content data (e.g., reviews, descripti...
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Article
Improved growth of bait microalgae Isochrysis and aquacultural wastewater treatment with mixotrophic culture
This research of mixotrophic microalgae Isochrysis 3011 with glycerol was combined with the treatment of aqua-cultural wastewater, different initial concentrations, and optimized light intensities. The algae grow...
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Article
Biocompatible, Easily Separated and Dispersed Silver Clusters for Imaging of Cancer Cells
The fabrication of silver nanoclusters with good cellular uptaking behaviors and the property of easy separation and redispersion without aggregation is a thorny problem. In this work, the nanosilica supported...
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Chapter and Conference Paper
An Overview of Existing Application of Recycled Concrete in China
As China is one of the largest producers of construction and demolition (C&D) waste, it is of great importance to recycle this waste. C&D waste has great recycling possibilities and could be reproduced into re...
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Article
Candidate gene analysis of watermelon stripe pattern locus ClSP ongoing recombination suppression
Using two segregating population, watermelon stripe pattern underlying gene ClSP was delimited to a 611.78 Kb region, consisting of four discrete haplobloc...