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  1. Article

    Open Access

    Identification of diagnostic markers for moyamoya disease by combining bulk RNA-sequencing analysis and machine learning

    Moyamoya disease (MMD) remains a chronic progressive cerebrovascular disease with unknown etiology. A growing number of reports describe the development of MMD relevant to infection or autoimmune diseases. Ide...

    Yifan Xu, Bing Chen, Zhongxiang Guo, Cheng Chen, Chao Wang, Han Zhou in Scientific Reports (2024)

  2. Article

    Open Access

    The value of indocyanine green-FLOW800 in microvasculature for predicting cerebral hyperperfusion syndrome in moyamoya disease patients

    Among the notable complications of direct hemodynamic reconstruction for moyamoya disease (MMD) is cerebral hyperperfusion syndrome (CHS). In this study, we evaluated hemodynamic changes in small regional micr...

    Zhongxiang Guo, Zhaohui Yan, Fan Qu, Dekui Cheng, Chao Wang in Scientific Reports (2023)

  3. Article

    Open Access

    Research on the effectiveness of a intersection risk warning system based on driving simulation experiment

    In order to improve the traffic safety condition of intersections, a real-time traffic conflict risk warning system (RTCRWS) is proposed for uncontrolled intersections. To evaluate the effectiveness of this sy...

    Yiwen Zhou, Fengxiang Guo, Wenchen Yang, Huasen Wan in Scientific Reports (2022)

  4. Article

    Open Access

    NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1

    Despite the substantial impact of post-translational modifications on programmed cell death 1 ligand 1 (PD-L1), its importance in therapeutic resistance in pancreatic cancer remains poorly defined. Here, we de...

    **aozhen Zhang, **ng Huang, Jian Xu, Enliang Li, Mengyi Lao in Nature Communications (2021)

  5. Article

    Open Access

    Reprogramming of Seed Metabolism Facilitates Pre-harvest Sprouting Resistance of Wheat

    Pre-harvest sprouting (PHS) is a worldwide problem for wheat production and transgene antisense-thioredoxin-s (anti-trx-s) facilitates outstanding resistance. To understand the molecular details of PHS resistance...

    Caixiang Liu, Feng Ding, Fuhua Hao, Men Yu, Hehua Lei, **angyu Wu in Scientific Reports (2016)

  6. No Access

    Article

    An improved coupling reaction for the preparation of pyridylethynyl benzonitrile compounds

    An improved coupling reaction between aromatic ring and acetylene triple bond catalyzed by palladium (0) catalyses for the preparation of pyridylethynyl benzonitrile compounds is described. Efforts were made t...

    Zhiyong Wang, Wenbin Lin, Chao Jiang, Qingxiang Guo in Chinese Science Bulletin (2001)

  7. No Access

    Article

    Enthalpy-entropy compensation in protein unfolding

    Enthalpy-entropy compensation was found to be a universal law in protein unfolding based on over 3000 experimental data. Water molecular reorganization accompanying the protein unfolding was suggested as the o...

    Lei Liu, Chao Yang, Qingxiang Guo in Chinese Science Bulletin (2000)