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  1. Article

    Open Access

    Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells

    Therapeutic strategies to treat pancreatic ductal adenocarcinoma (PDAC) remain unsatisfying and limited. Therefore, it is imperative to fully determine the mechanisms underlying PDAC progression. In the presen...

    Mengyi Lao, **aozhen Zhang, Tao Ma, Jian Xu, Hanshen Yang, Yi Duan in Oncogene (2021)

  2. Article

    Open Access

    The AKT-independent MET–V-ATPase–MTOR axis suppresses liver cancer vaccination

    Despite recent progress in hepatitis treatment, there have been no significant advances in the development of liver cancer vaccines in recent years. In this study, we investigated the regulatory effect and pot...

    **ng Huang, **ngyuan Xu, Xun Wang, Tianyu Tang in Signal Transduction and Targeted Therapy (2020)

  3. Article

    Open Access

    Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors

    Calorie restriction (CR) prevents obesity and exerts anticancer effects in many preclinical models. CR is also increasingly being used in cancer patients as a sensitizing strategy prior to chemotherapy regimen...

    Laura M. Lashinger, Ciara H. O’Flanagan, Sarah M. Dunlap in Cancer & Metabolism (2016)