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  1. Article

    Open Access

    Causal relationship between bone mineral density and intervertebral disc degeneration: a univariate and multivariable mendelian randomization study

    Although previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration (IDD), the causal relationship between them remains unclear. Evidence fro...

    Luming Li, Dawei Li, Ziming Geng, Zhenxin Huo… in BMC Musculoskeletal Disorders (2024)

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  2. No Access

    Article

    ASO Visual Abstract: Sintilimab Plus Modified FOLFIRINOX in Metastatic or Recurrent Pancreatic Cancer: The Randomized Phase II CISPD3 Trial

    Qihan Fu MD, Yiwen Chen MD, Dabing Huang MS… in Annals of Surgical Oncology (2023)

  3. No Access

    Article

    Sintilimab Plus Modified FOLFIRINOX in Metastatic or Recurrent Pancreatic Cancer: The Randomized Phase II CISPD3 Trial

    Folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) or modified FOLFIRINOX (mFFX) is the first-line standard of care for metastatic pancreatic adenocarcinoma; effective and safe treatment stra...

    Qihan Fu MD, Yiwen Chen MD, Dabing Huang MS… in Annals of Surgical Oncology (2023)

  4. No Access

    Article

    Lycorine induces apoptosis of acute myeloid leukemia cells and inhibits triglyceride production via binding and targeting FABP5

    Acute myeloid leukemia (AML) is the most common hematopoietic malignancy with abnormal lipid metabolism. However, currently available information on the involvement of the alterations in lipid metabolism in AM...

    **nming Liang, Wenli Fu, YuHui Peng, Juanjuan Duan, Ting Zhang… in Annals of Hematology (2023)

  5. No Access

    Article

    Exosomes from bone marrow-derived mesenchymal stem cells facilitate corneal wound healing via regulating the p44/42 MAPK pathway

    This study was aimed at exploring the function of Exosomes isolated from bone marrow-derived mesenchymal stem cells (BMSC-Exos) in corneal wound healing and at revealing the underlying mechanisms involving the...

    ** Zhou, Yuanyuan Ding, Yongqiang Zhang… in Graefe's Archive for Clinical and Experime… (2023)

  6. Article

    Open Access

    A clinical and biomechanical comparison of INFIX plus single versus double sacroiliac screw fixation for unstable pelvic ring injury

    The aim of this study is to compare the clinical and biomechanical outcome of INFIX plus single with two sacroiliac screw fixation for unstable pelvic fractures of Type C.

    Hongfen Chen, Chao Ding, Yongqiang Liu… in Journal of Orthopaedic Surgery and Research (2022)

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  7. Article

    Open Access

    Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells

    Therapeutic strategies to treat pancreatic ductal adenocarcinoma (PDAC) remain unsatisfying and limited. Therefore, it is imperative to fully determine the mechanisms underlying PDAC progression. In the presen...

    Mengyi Lao, **aozhen Zhang, Tao Ma, Jian Xu, Hanshen Yang, Yi Duan… in Oncogene (2021)

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  8. Article

    Open Access

    The AKT-independent MET–V-ATPase–MTOR axis suppresses liver cancer vaccination

    Despite recent progress in hepatitis treatment, there have been no significant advances in the development of liver cancer vaccines in recent years. In this study, we investigated the regulatory effect and pot...

    **ng Huang, **ngyuan Xu, Xun Wang, Tianyu Tang… in Signal Transduction and Targeted Therapy (2020)

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