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Article
Defect-engineered chiral metal–organic frameworks
Chirality has an important impact on chemical and biological research, as most active substances are chiral. In recent decades, metal–organic frameworks (MOFs), which are assembled from metal ions or clusters ...
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Article
Open AccessA diagnostic model for Parkinson’s disease based on circadian rhythm-related genes
Circadian rhythm (CR) disturbance is intricately associated with Parkinson’s disease (PD). However, the involvement of CR-related mechanisms in the pathogenesis and progression of PD remains elusive.
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Article
pH and redox dual response nano-suppository for the treatment of ulcerative colitis
To improve treatment compliance and reach sustained and controlled drug release in the colon, we developed a hollow mesoporous silica nano-suppository that responded to both pH and redox stimuli. Firstly, we p...
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Article
Ultrasensitive determination of quercetin using electrochemical sensor based on nickel do** zinc-based zeolite imidazole frame with a four-point star morphology
At present, achieving the electrochemical trace detection (picomole per liter level) with high sensitivity of quercetin is rare. In this work, the nickel-doped zinc-based zeolite imidazole framework with a fou...
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Article
Involvement of energy and cell wall metabolisms in chilling tolerance improved by hydrogen sulfide in cold-stored tomato fruits
Hydrogen sulfide improved cold resistance of tomato fruits by regulating energy metabolism and delaying cell wall degradation, thereby alleviating the damage of cold storage on fruits.
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Article
Modeling of extreme waves in the South China Sea under the influence of tropical cyclones: long-term statistical perspective in **sha reef islands
Comprehensive research on the distribution of extreme waves in the South China Sea (SCS), particularly within the proximity of reef islands is notably scarce. This study investigates the extreme wave distribut...
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Article
Simulation of γ-Ray Radiation Shielding Utilizing Gd2O3/Bi2O3/Epoxy Resin
In order to meet the requirement of radiation shielding caused by medical isotopes, nuclear reactors, and industrial facilities, gamma shielding effect of epoxy resin base added with Gd2O3/Bi2O3 particles was stu...
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Article
Ultrashort wave diathermy inhibits pulmonary inflammation in mice with acute lung injury in a HSP70 independent way: a pilot study
Acute lung injury (ALI) is a clinical syndrome characterized by pulmonary inflammation. Ultrashort wave diathermy (USWD) has been shown to be effective at in inhibiting ALI inflammation, although the underlyin...
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Article
Wedelia chinensis-derived biomass porous carbon as anode material for high performance sodium/potassium-ion batteries
Sodium-ion batteries (SIBs) and potassium-ion batteries (PIBs) are potential alternatives of lithium-ion batteries (LIBs) due to the abundant and cost-effective availability of sodium and potassium resources. ...
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Article
Open AccessHeat stress induces calcium dyshomeostasis to subsequent cognitive impairment through ERS-mediated apoptosis via SERCA/PERK/eIF2α pathway
Heat exposure is an environmental stressor that has been associated with cognitive impairment. However, the neural mechanisms that underlie this phenomenon have yet to be extensively investigated. The Morris w...
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Article
Identification of Prolactinoma in Pituitary Neuroendocrine Tumors Using Radiomics Analysis Based on Multiparameter MRI
This study aims to investigate the feasibility of preoperatively predicting histological subtypes of pituitary neuroendocrine tumors (PitNETs) using machine learning and radiomics based on multiparameter MRI. ...
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Article
Open AccessNecessity for higher teicoplanin doses in older adults: a multicenter prospective observational study in China
Many older adult patients receive low-dose teicoplanin with varied regimens, leading to a lack of clarity on its optimal regimens and toxicity profiles in China. This study aimed to clarify these aspects by an...
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Article
Effect of Electric Current Pulse on the Interfacial Reaction Between Molten Steel and SEN During Continuous Casting of Ultra-Low Carbon Steel
As an important refractory material in the continuous casting process, the clogging of submerged entry nozzle (SEN) can negatively affect the quality of the slab. In this paper, the effect of electric current ...
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Article
Enrichment of C17:0-rich saturated fatty acids from sheep tail fat for adjuvant therapy of non-small-cell lung cancer
Heptadecanoic acid (C17:0), an odd-chain saturated fatty acid (OCSFA) in ruminant lipid, has been demonstrated to be potential for treating cancers. Our results also showed that sheep tail fat (STF) with highe...
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Article
From seawater to hydrogen via direct photocatalytic vapor splitting: A review on device design and system integration
Solar-driven hydrogen production from seawater attracts great interest for its emerging role in decarbonizing global energy consumption. Given the complexity of natural seawater content, photocatalytic vapor s...
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Article
Disruption of PABPN1 phase separation by SNRPD2 drives colorectal cancer cell proliferation and migration through promoting alternative polyadenylation of CTNNBIP1
Generally shortened 3′ UTR due to alternative polyadenylation (APA) is widely observed in cancer, but its regulation mechanisms for cancer are not well characterized. Here, with profiling of APA in colorectal ...
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Article
Improved Streamflow Simulation by Assimilating In Situ Soil Moisture in Lumped and Distributed Approaches of a Hydrological Model in a Headwater Catchment
Soil moisture data assimilation (SM-DA) is a valuable approach for enhancing streamflow prediction in rainfall-runoff models. However, most studies have focused on incorporating remotely sensed SM, and their r...
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Article
Open AccessThe neurocognitive mechanism linking temperature and humidity with miners’ alertness: an fNIRS study
As the depth of coal mining increases, the temperature and humidity of the underground environment also rise, which can negatively impact the physiological health of miners, and may even pose a threat to their...
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Article
Open AccessGeneration and application of immortalized sheep fetal fibroblast cell line
Primary sheep fetal fibroblasts (SFFCs) have emerged as a valuable resource for investigating the molecular and pathogenic mechanisms of orf viruses (ORFV). However, their utilization is considerably restricte...
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Article
Nitric Oxide Promotes Adventitious Rooting in Cucumber Under Drought Stress Through Regulating Ascorbate Glutathione Cycle and Protein S-Nitrosylation
Drought stress can impair plant growth and development. Nitric oxide (NO), a gas signaling molecule, delays injuries caused by abiotic stress. This study explored the roles of NO during adventitious rooting in...
