75 Result(s)

Article

Drug resistance mechanisms and treatment strategies mediated by Ubiquitin-Specific Proteases (USPs) in cancers: new directions and therapeutic options

Drug resistance represents a significant obstacle in cancer treatment, underscoring the need for the discovery of novel therapeutic targets. Ubiquitin-specific proteases (USPs), a subclass of deubiquitinating ...

Hongli Gao, Zhuo **, **gwei Dai, **qi Xue, **n Guan, Liang Zhao… in Molecular Cancer (2024)

Article

Impact of AML1/ETO Fusion on the Efficacy of Venetoclax Plus Hypomethylating Agents in Newly Diagnosed Acute Myeloid Leukemia

AML1/ETO fusion confers favorable prognosis in acute myeloid leukemia (AML) treated with intensive chemotherapy (IC). However, the impact of AML1/ETO fusion on the efficacy of venetoclax in the treatment of AML i...

Dian **, Haoguang Chen, **gsong He, Yi Li, Gaofeng Zheng, Yang Yang… in Targeted Oncology (2024)

Article

Incidence and risk factors for febrile neutropenia of patients with diffuse large B-cell lymphoma receiving R-CHOP-21 in China

Febrile neutropenia (FN) is a serious complication of patients with diffuse large B-cell lymphoma (DLBCL) receiving R-CHOP-21. The prophylactic use of granulocyte colony–stimulating factors (G-CSFs) can signif...

Wenshuai Zheng, Zhaoguang Chen, Shibin Zhu, Longcan Cheng… in Supportive Care in Cancer (2023)

Article

Identification of m6A-associated genes as prognostic and immune-associated biomarkers in Wilms tumor

Wilms tumor (WT) is a common renal malignant tumor in children. We aimed to investigate the potential prognostic value of m6A-related genes and their relationship to the immune microenvironment in WT.

Yingquan Zhuo, Wengqi Zhang, Jun Du, Hua Jiang, Guangtang Chen… in Discover Oncology (2023)

Article

SOX combined with sintilimab versus SOX alone in the perioperative management of locally advanced gastric cancer: a propensity score–matched analysis

To evaluate the efficacy of SOX combined with a programmed cell death protein-1 (PD-1) inhibitor compared with SOX alone in the perioperative management of locally advanced gastric cancer and to explore biomar...

**ngmao Huang, **gquan Fang, Ling Huang, Hang Chen, Han Chen… in Gastric Cancer (2023)

Article

Prognostic analysis of prostaglandin D2 synthase in diffuse large B-cell lymphoma

We aimed to analyse the correlation between prostaglandin D2 synthase (PTGDS) and a diffuse large B-cell lymphoma (DLBCL) prognosis.

Jiesong Wang, Yun Xu, Wei Yu, Yanbin Zheng, Hongming He… in Holistic Integrative Oncology (2023)

Article

Development and validation of a point-based scoring system for predicting axillary lymph node metastasis and disease outcome in breast cancer using clinicopathological and multiparametric MRI features

Axillary lymph node (ALN) metastasis is used to select treatment strategies and define the prognosis in breast cancer (BC) patients and is typically assessed using an invasive procedure. Noninvasive, simple, a...

**aofeng Chen, Zhiqi Yang, Ruibin Huang, Yue Li, Yuting Liao, Gui** Li… in Cancer Imaging (2023)

Article

Biparametric magnetic resonance imaging-based radiomics features for prediction of lymphovascular invasion in rectal cancer

Preoperative assessment of lymphovascular invasion(LVI) of rectal cancer has very important clinical significance. However, accurate preoperative imaging evaluation of LVI is highly challenging because the res...

Pengfei Tong, Danqi Sun, Guangqiang Chen, Jianming Ni, Yonggang Li in BMC Cancer (2023)

Article

Quantitative parameters of dynamic contrast-enhanced magnetic resonance imaging to predict lymphovascular invasion and survival outcome in breast cancer

Lymphovascular invasion (LVI) predicts a poor outcome of breast cancer (BC), but LVI can only be postoperatively diagnosed by histopathology. We aimed to determine whether quantitative parameters of dynamic co...

Tianfu Lai, **aofeng Chen, Zhiqi Yang, Ruibin Huang, Yuting Liao… in Cancer Imaging (2022)

Article

Targeting TM4SF1 exhibits therapeutic potential via inhibition of cancer stem cells

Guang Chen, **aofei She, Yanxin Yin, Junxian Ma… in Signal Transduction and Targeted Therapy (2022)

Article

The value of diffusion kurtosis imaging and intravoxel incoherent motion quantitative parameters in predicting synchronous distant metastasis of rectal cancer

The incidence and mortality rate of rectal cancer are still high, the metastasis of rectal cancer are main causes of death. The control of the distant metastasis is one of the main concerns in the treatment of...

Xue Ding, Danqi Sun, Qiuchen Guo, Yeting Li, Hao Chen, **aoxiao Dai… in BMC Cancer (2022)

Article

Diagnostic performance of simplified TI-RADS for malignant thyroid nodules: comparison with 2017 ACR-TI-RADS and 2020 C-TI-RADS

The aim of this study is to propose a new TI-RADS and compare it with the American College of Radiology (2017 ACR)-TI-RADS and the 2020 Chinese (2020 C)-TI-RADS.

Zhiguang Chen, Yue Du, Linggang Cheng, Yukang Zhang, Shuai Zheng, Rui Li… in Cancer Imaging (2022)

Article

Changes in bone mineral density after bariatric surgery in patients of different ages or patients with different postoperative periods: a systematic review and meta-analysis

To assess changes in bone mineral density (BMD) following bariatric surgery (BS) in patients with different bone sites, postoperative periods and ages. Twenty-two studies were included. Femoral neck (FN) BMD d...

**aodan Ou, Mingguang Chen, Lizhen Xu, Wei Lin… in European Journal of Medical Research (2022)