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Article
Open AccessBarbed arrow-like structure membrane with ultra-high rectification coefficient enables ultra-fast, highly-sensitive lateral-flow assay of cTnI
Acute myocardial infarction (AMI) has become a public health disease threatening public life safety due to its high mortality. The lateral-flow assay (LFA) of a typical cardiac biomarker, troponin I (cTnI), is...
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Article
Open AccessExhaled VOC detection in lung cancer screening: a comprehensive meta-analysis
Lung cancer (LC), characterized by high incidence and mortality rates, presents a significant challenge in oncology. Despite advancements in treatments, early detection remains crucial for improving patient ou...
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Article
Open AccessThe activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions: insights from a single-arm, phase II trial
Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) protein significantly improve survival in patients with advanced non-small-cell lung cancer (NSCLC), but its impact on early-stage grou...
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Article
Open AccessRolapitant treats lung cancer by targeting deubiquitinase OTUD3
Lung cancer is cancer with the highest morbidity and mortality in the world and poses a serious threat to human health. Therefore, discovering new treatments is urgently needed to improve lung cancer prognosis...
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Chapter and Conference Paper
Numerical Simulation of Ba2+ Transport in Vertical Plastic Concrete Cutoff Barrier
Taking the vertical plastic concrete cutoff barrier in the Guizhou Tianzhu Chemical Phase II landfill as the research object, the Hydrus-2D finite element simulation software was used to investigate the migrat...
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Article
Open AccessRelay learning: a physically secure framework for clinical multi-site deep learning
Big data serves as the cornerstone for constructing real-world deep learning systems across various domains. In medicine and healthcare, a single clinical site lacks sufficient data, thus necessitating the inv...
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Article
Open AccessA surgical Decision-making scoring model for spontaneous ventilation- and mechanical ventilation-video-assisted thoracoscopic surgery in non-small-cell lung cancer patients
Spontaneous ventilation-video-assisted thoracoscopic surgery (SV-VATS) has been applied to non-small cell lung cancer (NSCLC) patients in many centers. Since it remains a new and challenging surgical technique...
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Article
Risk map** of lung cancer: a comprehensive appraisal of published meta-analyses incorporating Mendelian randomization studies
A comprehensive appraisal of published meta-analyses incorporating Mendelian randomization studies was performed to map the different risk factors and assess the causality for lung cancer.
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Article
The relationship of airflow limitation with lung squamous cell carcinoma: evidence from mendelian randomization analysis
Observational studies showed associations between smoking, and airflow limitation, with lung squamous cell carcinoma (LUSC). However, the causal association of airflow limitation with LUSC and the modification...
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Article
Experimental Study on the Overall Cooling Effectiveness of Effusion-Cooling Ceramic Matrix Composite Platform
Ceramic matrix composite (CMC), with higher thermal limit and lower density relative to the superalloy, is regarded as the most important structural material for modern gas turbine engines. However, the anisot...
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Article
Open Access“Major pathologic response” in lymph nodes: a modified nodal classification for non-small cell lung cancer patients treated with neoadjuvant immunochemotherapy
We aim to examine the prognostic value of major pathologic response in metastatic lymph nodes (mLN-MPR) after immunochemotherapy in non-small cell lung cancer (NSCLC), and demonstrate the pathological characte...
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Article
Predicting EGFR mutation status in lung adenocarcinoma presenting as ground-glass opacity: utilizing radiomics model in clinical translation
This study aimed to establish a non-invasive radiomics model based on computed tomography (CT), with favorable sensitivity and specificity to predict EGFR mutation status in GGO-featured lung adenocarcinoma su...
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Article
Artificial intelligence for stepwise diagnosis and monitoring of COVID-19
Main challenges for COVID-19 include the lack of a rapid diagnostic test, a suitable tool to monitor and predict a patient’s clinical course and an efficient way for data sharing among multicenters. We thus de...
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Article
Relationship between lung function and lung cancer risk: a pooled analysis of cohorts plus Mendelian randomization study
Since little consensus has been reached on whether milder reduction in forced expiratory volume in 1 s (FEV1) increases lung cancer incidence, we conducted a meta-analysis and performed Mendelian randomization (M...
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Article
Open AccessThe impact of postoperative EGFR-TKIs treatment on residual GGO lesions after resection for lung cancer
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Article
Open AccessAddendum: Early triage of critically ill COVID-19 patients using deep learning
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Article
Breast cancer risk in patients with polycystic ovary syndrome: a Mendelian randomization analysis
The association between polycystic ovary syndrome (PCOS) and breast cancer remains inconclusive. Conventional observational studies are susceptible to inverse causality and potential confounders. With a Mendel...
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Article
Association between the use of aspirin and risk of lung cancer: results from pooled cohorts and Mendelian randomization analyses
We aimed to elucidate the associations between aspirin use with risk of lung cancer, by conducting a meta-analysis and Mendelian randomization (MR) analyses from published Genome-Wide Association Studies (GWAS).
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Article
Open AccessEffect of microwave ablation treatment of hepatic malignancies on serum cytokine levels
Microwave ablation (MWA) is widely used to treat unresectable primary and secondary malignancies of the liver, and a limited number of studies indicate that ablation can cause not only necrosis at the in situ ...
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Article
Cancer risks in patients with vitiligo: a Mendelian randomization study
Few studies have investigated the relationship between vitiligo and risks of various types of cancers, especially those other than skin cancer. Conventional observational studies are susceptible to potential c...
