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122 Result(s)
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Open AccessAuthor Correction: Unravelling the spatial directionality of urban mobility
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Open AccessForecasting the commuting generation using metropolis-informed GCN and the topological commuter portrait
Understanding commuter traffic in transportation networks is crucial for sustainable urban planning with commuting generation forecasts operating as a pivotal stage in commuter traffic modeling. Overcoming cha...
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Open AccessUnravelling the spatial directionality of urban mobility
As it is central to sustainable urban development, urban mobility has primarily been scrutinised for its scaling and hierarchical properties. However, traditional analyses frequently overlook spatial direction...
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Open AccessWhole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers
The role for routine whole genome and transcriptome analysis (WGTA) for poor prognosis pediatric cancers remains undetermined. Here, we characterize somatic mutations, structural rearrangements, copy number va...
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Open AccessDevelopment and evaluation of time-resolved rapid immunofluorescence test for detection of TSOL18 specific antibody in porcine cysticercosis infections
Porcine cysticercosis, a serious zoonotic parasitic disease, is caused by the larvae of Taenia solium and has been acknowledged by the World Organization for Animal Health. The current detection methods of Cystic...
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Open AccessEffect of health rights accessibility on the urban integration of minority rural migrants in China: a cross-sectional study
Accessing health rights is an integral component of people’s aspirations for a better life. Existing discussions and evaluations regarding the accessibility of health rights for minority rural migrants are ins...
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Open AccessHow does choice of residential community affect the social integration of rural migrants: insights from China
The construction of public space is a new and important way to integrate rural migrants into urban society. Existing studies mainly discussed the factors affecting the social integration of rural migrants from...
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Open AccessDown-regulation of MKP-1 in hippocampus protects against stress-induced depression-like behaviors and neuroinflammation
Chronic stress is the primary environmental risk factor for major depressive disorder (MDD), and there is compelling evidence that neuroinflammation is the major pathomechanism linking chronic stress to MDD. M...
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Open AccessA new model for residential location choice using residential trajectory data
Traditional residential location choice (RLC) models are based on the characteristics of location and demographics, revealing important patterns of RLC, but no RLC models have yet incorporated individual prefe...
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Open AccessCPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma
Glioma is the most common primary malignant brain tumor in adults and remains an incurable disease at present. Thus, there is an urgent need for progress in finding novel molecular mechanisms that control the ...
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Open AccessDiscovering the long-term effects of COVID-19 on jobs–housing relocation
Jobs–housing relocation plays a crucial role in urban spatial restructuring and development. As the COVID-19 pandemic has dramatically altered the form of human mobility, it is likely to have affected individu...
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Open AccessFunctional significance of cholesterol metabolism in cancer: from threat to treatment
Cholesterol is an essential structural component of membranes that contributes to membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the maintenance of cellular activities. Recen...
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Open AccessSocial inequality of urban park use during the COVID-19 pandemic
Although many studies have examined social inequalities related to urban parks, there is limited knowledge about the social inequalities of urban park use during crises. By integrating a large amount of mobile...
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Open AccessTiming of interval debulking surgery and postoperative chemotherapy after neoadjuvant chemotherapy in advanced epithelial ovarian cancer: a multicenter real-world study
To investigate the prognostic relevance of the time to interval debulking surgery (TTS) and the time to postoperative adjuvant chemotherapy (TTC) after the completion of neoadjuvant chemotherapy (NACT).
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Open AccessDevelopment and validation of a nomogram to predict cancer-specific survival of mucinous epithelial ovarian cancer after cytoreductive surgery
Mucinous epithelial ovarian cancer (mEOC) is a relatively uncommon subtype of ovarian cancer with special prognostic features, but there is insufficient research in this area. This study aimed to develop a nom...
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Open AccessAssessment of an exhaled breath test using ultraviolet photoionization time-of-flight mass spectrometry for the monitoring of kidney transplant recipients
Continuous monitoring for immunosuppressive status, infection and complications are a must for kidney transplantation (KTx) recipients. Traditional monitoring including blood sampling and kidney biopsy, which ...
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Open AccessMinocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)
Mutations in colony-stimulating factor 1 receptor (CSF1R) are known to cause adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), which has been recently demonstrated as a primary m...
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Open AccessUncovering spatial and social gaps in rural mobility via mobile phone big data
Rural mobility inequality is an important aspect of inequality-focused Sustainable Development Goals. To reduce inequality and promote global sustainable development, more insight is needed into human mobility...
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Open AccessA two-generational SU(7) model with extended weak sector: mass hierarchies, mixings, and the flavor non-universality
We study a possible gauge symmetry breaking pattern in an SU(7) grand unified theory, which describes the mass origins of all electrically charged SM fermions of the second and the third generations. Two inter...
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Open Accessm6A methyltransferase METTL3 programs CD4+ T-cell activation and effector T-cell differentiation in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disorder in which excessive CD4+ T-cell activation and imbalanced effector T-cell differentiation play critical roles. Recent studies have implied a potential a...