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  1. Article

    Open Access

    ZBP-89 reduces histone deacetylase 3 by degrading IkappaB in the presence of Pin1

    Histone deacetylase 3 (HDAC3) is overexpressed in cancers and its inhibition enhances anti-tumor chemotherapy. ZBP-89, a transcription factor, can induce pro-apoptotic Bak and reduce HDAC3 but the mechanism is...

    Cai Guo Ye, Li** Liu, George G Chen, **ao Lin Tang… in Journal of Translational Medicine (2015)

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  2. No Access

    Article

    Cell death induced by ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid in anaplastic thyroid carcinoma cells is via a mitochondrial-mediated pathway

    The chemical compound ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F), isolated from the Chinese herbal medicine plant Pteris semipinnata L, has been known to exert antitumor activity. However, the molecula...

    Z. M. Liu, G. G. Chen, A. C. Vlantis, N.-C. Liang, Y.-F. Deng… in Apoptosis (2005)