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  1. Article

    Open Access

    A new prognostic model based on gamma-delta T cells for predicting the risk and aiding in the treatment of clear cell renal cell carcinoma

    ccRCC is the prevailing form of RCC, accounting for the majority of cases. The formation of cancer and the body's ability to fight against tumors are strongly connected to Gamma delta (γδ) T cells.

    Yaqian Wu, Mengfei Yao, Zonglong Wu, Lulin Ma, Cheng Liu in Discover Oncology (2024)

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  2. Article

    Open Access

    Diethyldithiocarbamate-copper complex (CuET) inhibits colorectal cancer progression via miR-16-5p and 15b-5p/ALDH1A3/PKM2 axis-mediated aerobic glycolysis pathway

    Exploring novel anticancer drugs to optimize the efficacy may provide a benefit for the treatment of colorectal cancer (CRC). Disulfiram (DSF), as an antialcoholism drug, is metabolized into diethyldithiocarba...

    **n Huang, Yichao Hou, **aoling Weng, Wen**g Pang, Lidan Hou, Yu Liang… in Oncogenesis (2021)

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  3. Article

    Open Access

    Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway

    The development of chemoresistance remains a major challenge that accounts for colorectal cancer (CRC) lethality. Dichloroacetate (DCA) was originally used as a metabolic regulator in the treatment of metaboli...

    Yu Liang, Lidan Hou, Lin**g Li, Lei Li, Liming Zhu, Yu Wang, **n Huang… in Oncogene (2020)

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