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  1. Article

    Open Access

    Diethyldithiocarbamate-copper complex (CuET) inhibits colorectal cancer progression via miR-16-5p and 15b-5p/ALDH1A3/PKM2 axis-mediated aerobic glycolysis pathway

    Exploring novel anticancer drugs to optimize the efficacy may provide a benefit for the treatment of colorectal cancer (CRC). Disulfiram (DSF), as an antialcoholism drug, is metabolized into diethyldithiocarba...

    **n Huang, Yichao Hou, **aoling Weng, Wen**g Pang, Lidan Hou, Yu Liang… in Oncogenesis (2021)

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  2. Article

    Open Access

    Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway

    The development of chemoresistance remains a major challenge that accounts for colorectal cancer (CRC) lethality. Dichloroacetate (DCA) was originally used as a metabolic regulator in the treatment of metaboli...

    Yu Liang, Lidan Hou, Lin**g Li, Lei Li, Liming Zhu, Yu Wang, **n Huang… in Oncogene (2020)

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