49 Result(s)
within
**gang Zheng
Life Sciences
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Article
Open AccessComposition and diversity of soil microbial communities change by introducing Phallus impudicus into a Gastrodia elata Bl.-based soil
The Gastrodia elata Bl. is an orchid, and its growth demands the presence of Armillaria species. The strong competitiveness of Armillaria species has always been a concern of major threat to other soil organisms,...
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A strain of Vibrio alginolyticus isolated from Azumapecten farreri and its pathogenic mechanism using CRISPR-Cas9 technology
Scallops have become an important aquaculture species in China because they contain high-quality protein, and scallops are important health food that combines multiple effects and high economic benefits. Howev...
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Open AccessPhysiological, anatomical and quality indexes of root tuber formation and development in chayote (Sechium edule)
Chayote is an underutilized species of Cucurbitaceae. It is rich in nutrients such as protein, minerals, phenols and its extracts have anti-cardiovascular and anti-cancer effects, making it a versatile plant f...
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The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
PIWI-clade proteins harness piRNAs of 24–33 nt in length. Of great puzzles are how PIWI-clade proteins incorporate piRNAs of different sizes and whether the size matters to PIWI/piRNA function. Here we report ...
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Open AccessChromosome-level genome of black cutworm provides novel insights into polyphagy and seasonal migration in insects
The black cutworm, Agrotis ipsilon, is a serious global underground pest. Its distinct phenotypic traits, especially its polyphagy and ability to migrate long distances, contribute to its widening distribution an...
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LncRNA UCA1 epigenetically suppresses APAF1 expression to mediate the protective effect of sevoflurane against myocardial ischemia–reperfusion injury
Myocardial ischemia–reperfusion injury (MI/RI) is a leading cause of death globally. Whereas some long noncoding RNAs (lncRNAs) are known to participate in the progression of MI/RI, the role of urothelial carc...
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Open AccessMFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis
Intervertebral disc degeneration (IVDD) is a chronic age-related degenerative disease accompanied by complex pathophysiological mechanisms. Increasing evidence indicates that NLRP3 inflammasome mediated pyropt...
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Flavonoid components and gene expression analysis reveal flower pigmentation difference between Magnolia biondii and its variety M. biondii var. purpurascens
Compared with Magnolia biondii , higher anthocyanin content and higher expression level of related structural genes involved in flavonoids biosynthesis were...
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Article
YAP/TAZ drives cell proliferation and tumour growth via a polyamine–eIF5A hypusination–LSD1 axis
Metabolic reprogramming is central to oncogene-induced tumorigenesis by providing the necessary building blocks and energy sources, but how oncogenic signalling controls metabolites that play regulatory roles ...
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Open AccessTargeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is a lethal cardiovascular disease, and there is no proven drug treatment for this condition. In this study, by using the Connectivity Map (CMap) approach, we explored naringeni...
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Open AccessComparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities
Studies of radiation interaction with tumor cells often take apoptosis as the desired results. However, mitotic catastrophe and senescence are also promoted by clinically relevant doses of radiation. Furthermo...
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Coexistence of endonuclease and exonuclease activities in a novel RecJ from Bacillus cereus
All RecJ proteins are known to date only perform exonuclease activity. The present study reports that a novel RecJ protein obtained from Bacillus cereus isolated from marine sediments has both endonuclease and ex...
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Open AccessCartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury
Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling, including angiotensin II (AngII) receptor type 1 (AT1) signaling, plays pivotal roles in vascular homeost...
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Open AccessMolecular map** of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Lesion mimics (LMs) are disease-like symptoms that occur randomly on plant green leaves in the absence of pathogens. A previous study showed that LMs are related to enhanced resistance to a broad spectrum of d...
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Open AccessSTING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway
Damaged deoxyribonucleic acid (DNA) is a primary pathologic factor for osteoarthritis (OA); however, the mechanism by which DNA damage drives OA is unclear. Previous research demonstrated that the cyclic GMP-A...
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Open AccessAn efficient autometallography approach to localize lead at ultra-structural levels of cultured cells
Understanding the precise intracellular localization of lead (Pb) is a key in deciphering processes in Pb-induced toxicology. However, it is a great challenge to trace Pb in vitro, especially in cultured cells. W...
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Comparative analyses of chloroplast genomes from 13 Lagerstroemia (Lythraceae) species: identification of highly divergent regions and inference of phylogenetic relationships
Seven divergence hotspots as plastid markers for DNA barcoding was selected, and the phylogeny of 13 Lagerstroemia species based on the cp genome data was reconstructed within Myrtales.
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Comparative profiling of roots small RNA expression and corresponding gene ontology and pathway analyses for low- and high-cadmium–accumulating genotypes of wheat in response to cadmium stress
MicroRNAs (miRNAs) participate in multiple biological processes in plant. Cd accumulation ability differs among varieties in wheat, but little is known about miRNAs and their function in Cd accumulation of whe...
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Develo** stripe rust resistant wheat (Triticum aestivum L.) lines with gene pyramiding strategy and marker-assisted selection
Stripe rust or yellow rust, caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most destructive diseases of wheat (Triticum aestivum L.) worldwide. Growing resistant cultivars is the most effectiv...
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Characterization and diagnostic marker development for Yr28-rga1 conferring stripe rust resistance in wheat
Stripe rust is one of the most devastating wheat diseases and develo** resistant cultivars is the most economical way to manage this disease. More than 80 stripe rust resistance genes (Yr genes) have formally b...
