15 Result(s)
within
**g-zhou Meng
Life Sciences
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Article
Full-length GSDME mediates pyroptosis independent from cleavage
Gasdermin (GSDM) family proteins, known as the executors of pyroptosis, undergo protease-mediated cleavage before inducing pyroptosis. We here discovered a form of pyroptosis mediated by full-length (FL) GSDME...
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Article
DNA loo** mediates cooperative transcription activation
Transcription factors respond to multilevel stimuli and co-occupy promoter regions of target genes to activate RNA polymerase (RNAP) in a cooperative manner. To decipher the molecular mechanism, here we report...
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Open AccessAn immortal porcine preadipocyte cell strain for efficient production of cell-cultured fat
Adding adipose cells to cell-cultured meat can provide a distinctive aroma and juicy texture similar to real meat. However, a significant challenge still exists in obtaining seed cells that can be propagated f...
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Article
Open AccessComparative genome anatomy reveals evolutionary insights into a unique amphitriploid fish
Triploids are rare in nature because of difficulties in meiotic and gametogenic processes, especially in vertebrates. The Carassius complex of cyprinid teleosts contains sexual tetraploid crucian carp/goldfish (C...
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Open AccessProteomics-based evaluation of the mechanism underlying vascular injury via DNA interstrand crosslinks, glutathione perturbation, mitogen-activated protein kinase, and Wnt and ErbB signaling pathways induced by crotonaldehyde
Crotonaldehyde (CRA)—one of the major environmental pollutants from tobacco smoke and industrial pollution—is associated with vascular injury (VI). We used proteomics to systematically characterize the present...
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Comparative analysis of the transcriptome, methylome, and metabolome during pollen abortion of a seedless citrus mutant
Pollen abortion could be mainly attributed to abnormal meiosis in the mutant. Multiomics analysis uncovered significant epigenetic variations between the mutant and its wild type during the pollen abortion pro...
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Open AccessWhole-transcriptome RNA sequencing reveals the global molecular responses and ceRNA regulatory network of mRNAs, lncRNAs, miRNAs and circRNAs in response to copper toxicity in Ziyang **angcheng (Citrus junos Sieb. Ex Tanaka)
Copper (Cu) toxicity has become a potential threat for citrus production, but little is known about related mechanisms. This study aims to uncover the global landscape of mRNAs, long non-coding RNAs (lncRNAs),...
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Mechanism underlying 2n male and female gamete formation in lemon via cytological and molecular marker analysis
The unreduced (2n) gametes have long been used in triploid breeding of citrus. In lemon, the previously reported mechanisms for 2n megagametophyte formation were controversial, whereas that for 2n pollen produ...
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Article
Retraction Note to: An assessment of transgenomics as a tool for gene discovery in Populus euphratica Oliv.
This article (Zhou et al. 2018) has been retracted by the authors because the sequence BIBAC 002A111F06 was incorrectly assigned to the wrong bacterial species. The BIBAC 002A111F06 sequence (GenBank Accession...
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RETRACTED ARTICLE: An assessment of transgenomics as a tool for gene discovery in Populus euphratica Oliv.
Transgenomics for gene discovery in Populus euphratica.
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Article
Open AccessOsteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of β-Catenin
The incidence and mortality of intrahepatic cholangiocarcinoma (ICC) are increasing worldwide in recent decades. Osteopontin (OPN) plays an important role in cancer metastasis, but its functional mechanism in ...
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Article
Effects of the Vrn-D1b allele associated with facultative growth habit on agronomic traits in common wheat
The Vrn-D1b allele associated with facultative growth habit was recently found in the wheat cultivars mostly distributed in the Yellow and Huai River Valley Winter Wheat Zone (YHWZ) in China. The objective of the...
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Article
α7nAChR is expressed in satellite cells at different myogenic status during skeletal muscle wound healing in rats
Recent study has reported that α7 nicotine acetylcholine receptor (α7nAChR) is expressed in regenerated multinucleated myotubes. But the distribution of α7nAChR in satellite cells in different myogenic status ...
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Article
Distribution of the Vrn-D1b allele associated with facultative growth habit in Chinese wheat accessions
Vernalization requirement in wheat is determined by allelic variation mainly at three loci, Vrn-A1, Vrn-B1 and Vrn-D1. Up to 2011 only two alleles at the Vrn-D1 locus were known. The dominant allele, now designat...
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Article
Transglutaminase-2 is Involved in Cell Apoptosis of Osteosarcoma Cell Line U2OS Under Hypoxia Condition
Osteosarcoma is the most common type of solid bone cancer, which is the second leading cause of cancer-related death. Hypoxia is an ordinary phenomenon in solid tumor tissues and can induce cell apoptosis but ...
