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  1. No Access

    Article

    Unveiling the secrets of diatom-mediated calcification: Implications for the biological pump

    Siliceous diatoms are one of the most prominent actors in the oceans, and they account for approximately 40% of the primary production and particulate organic carbon export flux. It is believed that changes in...

    Yiwen Pan, Yifan Li, Chen-Tung Arthur Chen, Zong-Pei Jiang in Science China Earth Sciences (2024)

  2. No Access

    Article

    Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice

    Enteroendocrine cells (EECs) and vagal afferent neurons constitute functional sensory units of the gut, which have been implicated in bottom-up modulation of brain functions. Sodium oligomannate (GV-971) has b...

    Hua-shan Gong, **g-pei Pan, Fei Guo, Mei-mei Wu, Li Dong in Acta Pharmacologica Sinica (2024)

  3. No Access

    Book and Conference Proceedings

    Genetic and Evolutionary Computing

    Proceedings of the Fifteenth International Conference on Genetic and Evolutionary Computing (Volume II), October 6-8, 2023, Kaohsiung, Taiwan

    Jeng-Shyang Pan, Zhigeng Pan, Pei Hu in Lecture Notes in Electrical Engineering (2024)

  4. Article

    Open Access

    Effects of dynamic and rigid implantation on biomechanical characteristics of different sagittal alignment lumbar after single- or double-level spinal fixations: a finite-element modeling study

    Although it is critical to understand the accelerated degeneration of adjacent segments after fusion, the biomechanical properties of the spine have not been thoroughly studied after various fusion techniques....

    Wei Wang, Chao Kong, Fumin Pan, Xueqing Wu in European Journal of Medical Research (2023)

  5. Article

    Open Access

    STCF conceptual design report (Volume 1): Physics & detector

    The super τ-charm facility (STCF) is an electron–positron collider proposed by the Chinese particle physics community. It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak lumino...

    M. Achasov, X. C. Ai, L. P. An, R. Aliberti, Q. An, X. Z. Bai in Frontiers of Physics (2023)

  6. No Access

    Article

    Subsecond periodic radio oscillations in a microquasar

    Powerful relativistic jets are one of the ubiquitous features of accreting black holes in all scales13. GRS 1915 + 105 is a well-known fast-spinning black-hole X-ray binary4 with a relativistic jet, termed a ‘mi...

    Pengfu Tian, ** Zhang, Wei Wang, Pei Wang, **aohui Sun, Jifeng Liu, Bing Zhang in Nature (2023)

  7. Article

    Open Access

    Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

    The bat coronaviruses (CoV) BANAL-20-52 and BANAL-20-236 are two newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) closely related coronaviruses (SC2r-CoV) and the genome of BANAL-2...

    **uyuan Ou, Ge Xu, Pei Li, Yan Liu, Fuwen Zan, Pan Liu, Jiaxin Hu in Cell Discovery (2023)

  8. Article

    Open Access

    LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis

    Inhibition of immunocyte infiltration and activation has been suggested to effectively ameliorate nonalcoholic steatohepatitis (NASH). Paired immunoglobulin-like receptor B (PirB) and its human ortholog recept...

    Dan-Pei Li, Li Huang, Ran-Ran Kan, **ao-Yu Meng, Shu-Yun Wang in Nature Communications (2023)

  9. Article

    Open Access

    The role of the genomic mutation signature and tumor mutation burden on relapse risk prediction in head and neck squamous cell carcinoma after concurrent chemoradiotherapy

    Personalized genetic profiling has focused on improving treatment efficacy and predicting risk stratification by identifying mutated genes and selecting targeted agents according to genetic testing. Therefore,...

    Hui-Ching Wang, Sin-Hua Moi, Leong-Perng Chan in Experimental & Molecular Medicine (2023)

  10. Article

    Open Access

    The functional change of the P2X7R containing the Ala348 to Thr polymorphism is associated with the pathogenesis of gout

    Our previous study has shown that ATP action on P2X7R could be the second signal to induce the onset of gouty arthritis. However, the functional changes of P2X7R single nucleotide polymorphisms (SNPs) on the e...

    Man-Yun Li, Xuan Fang, Yan Ma, **an-Yang Pan, **ao-Juan Dai in Scientific Reports (2023)

  11. No Access

    Article

    Synthesis of vanadium powder by magnesiothermic reduction of V2O3 in a reactive molten salt

    As an important strategic metal, vanadium is generally used to prepare special steels, titanium alloys, and hydrogen storage materials. A new method of producing vanadium (metal) powder from V2O3 using block Mg i...

    Da-peng Zhong, Gui-shang Pei, Jia-long Kang in Journal of Iron and Steel Research Interna… (2023)

  12. Article

    LOC101929709 promotes gastric cancer progression by aiding LIN28B to stabilize c-MYC mRNA

    LIN28B plays a critical role in the Warburg effect. However, its underlying mechanism remains elusive. Recently, it has been reported that LIN28B could collaborate with IGF2BP3, which can bind to m6A-modified ...

    Tong-peng Xu, Tao Yu, Meng-yan **e, Yuan Fang, Ting-ting Xu, Yu-tian Pan in Gastric Cancer (2023)

  13. No Access

    Book and Conference Proceedings

  14. Article

    Open Access

    Exclusive breastfeeding rate and related factors among mothers within maternal health WeChat groups in Jiaxing, Zhejiang province, China: a cross-sectional survey

    The health workers in Jiaxing of China have established maternal health WeChat groups for maternal health education and management since 2019. Pregnant women in Jiaxing are invited to join the WeChat groups an...

    Chun-Yan Fu, Xue-Juan Tang, Ling-Pei Pan in International Breastfeeding Journal (2022)

  15. Article

    Hypertension Exacerbates Severity and Outcomes of COVID-19 in Elderly Patients: A Retrospective Observational Study

    To evaluate the impact of hypertension on the clinical outcome of COVID-19 patients aged 60 years old and older.

    Li-song Dai, Meng-pei Zhu, Yu-min Li, Hong-mei Zhou in Current Medical Science (2022)

  16. Article

    Open Access

    Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer

    The genetic basis of colorectal cancer (CRC) and its clinical associations remain poorly understood due to limited samples or targeted genes in current studies. Here, we perform ultradeep whole-exome sequencin...

    Qi Zhao, Feng Wang, Yan-**ng Chen, Shifu Chen, Yi-Chen Yao in Nature Communications (2022)

  17. Article

    Open Access

    Maternal regulation of biliary disease in neonates via gut microbial metabolites

    Maternal seeding of the microbiome in neonates promotes a long-lasting biological footprint, but how it impacts disease susceptibility in early life remains unknown. We hypothesized that feeding butyrate to pr...

    Jai Junbae Jee, Li Yang, Pranavkumar Shivakumar, Pei-pei Xu in Nature Communications (2022)

  18. No Access

    Article

    Dietary riboflavin deficiency induces ariboflavinosis and esophageal epithelial atrophy in association with modification of gut microbiota in rats

    Riboflavin deficiency causes ariboflavinosis, a common nutritional deficiency disease. The purpose of this study is to investigate the effects of riboflavin deficiency on the important internal organs and its ...

    Feng Pan, Ling-Li Zhang, Hong-Jun Luo, Ye Chen, Lin Long in European Journal of Nutrition (2021)

  19. No Access

    Article

    Nanomaterial-based ROS-mediated strategies for combating bacteria and biofilms

    Nowadays, bacterial infection has become a severe threat to human health worldwide. The arising of antibiotic-resistant bacteria resulting from antibiotic abusing further adds the burden of bacterial infection...

    Wenjia **e, Shu Zhang, Fangwei Pan, Song Chen, Linna Zhong in Journal of Materials Research (2021)

  20. Article

    Open Access

    Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma

    Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with extremely skewed ethnic and geographic distributions. Increasing evidence indicates that targeting the tumor microenvironment (TME) represents a ...

    Yu-Pei Chen, Jian-Hua Yin, Wen-Fei Li, Han-Jie Li, Dong-** Chen in Cell Research (2020)

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