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Article
Open AccessDysfunction of duplicated pair rice histone acetyltransferases causes segregation distortion and an interspecific reproductive barrier
Postzygotic reproductive isolation, which results in the irreversible divergence of species, is commonly accompanied by hybrid sterility, necrosis/weakness, or lethality in the F1 or other offspring generations. ...
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Article
Gut commensal Christensenella minuta modulates host metabolism via acylated secondary bile acids
A strong correlation between gut microbes and host health has been observed in numerous gut metagenomic cohort studies. However, the underlying mechanisms governing host–microbe interactions in the gut remain ...
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Article
Open AccessOptimization of rice panicle architecture by specifically suppressing ligand–receptor pairs
Rice panicle architecture determines the grain number per panicle and therefore impacts grain yield. The OsER1–OsMKKK10–OsMKK4–OsMPK6 pathway shapes panicle architecture by regulating cytokinin metabolism. How...
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Article
Open AccessThe spatiotemporal matching pattern of Ezrin/Periaxin involved in myoblast differentiation and fusion and Charcot-Marie-Tooth disease-associated muscle atrophy
Clinically, Charcot-Marie-Tooth disease (CMT)-associated muscle atrophy still lacks effective treatment. Deletion and mutation of L-periaxin can be involved in CMT type 4F (CMT4F) by destroying the myelin shea...
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Article
A novel composite joint with corrugated web and cover plates for simultaneously improving anti-collapse resistance and seismic behavior
This paper presents a numerical study on the progressive collapse response of concrete-filled steel tube (CFST) composite joint. A novel beam-column connection by using corrugated web and cover plate is propos...
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Article
Open AccessContinuous exposure to isoprenaline reduced myotube size by delaying myoblast differentiation and fusion through the NFAT-MEF2C signaling pathway
We aimed to explore whether superfluous sympathetic activity affects myoblast differentiation, fusion, and myofiber types using a continuous single-dose isoprenaline exposure model in vitro and to further conf...
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Article
Open AccessCorrection: Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank
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Article
Effect of high magnetic field on solidification microstructure evolution of a Cu-Fe immiscible alloy
The liquid phase separation behavior and the evolution of the solidification microstructure of a binary Cu50Fe50 alloy were investigated under the conditions of without and with a 10 T magnetic field, with differ...
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Article
TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis
Global warming threatens crop production. G proteins mediate plant responses to multiple abiotic stresses. Here we identified a natural quantitative trait locus, TT2 (THERMOTOLERANCE 2), encoding a Gγ subunit, th...
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Article
Open AccessA rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance
Grain size is a key component trait of grain weight and yield. Numbers of quantitative trait loci (QTLs) have been identified in various bioprocesses, but there is still little known about how metabolism-relat...
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Article
Open AccessSpatio-temporal model of Meox1 expression control involvement of Sca-1-positive stem cells in neointima formation through the synergistic effect of Rho/CDC42 and SDF-1α/CXCR4
Neointimal hyperplasia remains a major obstacle in vascular regeneration. Sca-1-positive progenitor cells residing within the vascular adventitia play a crucial role in the assemblage of vascular smooth muscle...
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Article
Open AccessEnlightening the taxonomy darkness of human gut microbiomes with a cultured biobank
In gut microbiome studies, the cultured gut microbial resource plays essential roles, such as hel** to unravel gut microbial functions and host-microbe interactions. Although several major studies have been ...
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Article
Interface characteristic and mechanical performance of TiAl/Ti2AlNb diffusion bonding joint with pure Ti interlayer
Solid-state diffusion bonding (DB) of TiAl alloy and Ti2AlNb alloy was carried out using pure Ti as an interlayer at 1000 °C under 20 MPa for 60–120 min. The effects of bonding times on the interfacial microstruc...
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Article
An on-line fiber cutting-welding method for the fabrication of Fabry-Perot micro-cavity
A Fabry-Perot micro-cavity is fabricated by on-line fiber cutting-welding method. The asymmetrical fiber Fabry-Perot micro-cavity is designed and produced by cutting a standard single-mode fiber and welding th...
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Article
Open AccessUDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice
Grain size is an important component trait of grain yield, which is frequently threatened by abiotic stress. However, little is known about how grain yield and abiotic stress tolerance are regulated. Here, we ...
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Article
Open AccessNAL8 encodes a prohibitin that contributes to leaf and spikelet development by regulating mitochondria and chloroplasts stability in rice
Leaf morphology and spikelet number are two important traits associated with grain yield. To understand how genes coordinating with sink and sources of cereal crops is important for grain yield improvement gui...
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Article
Pre-treatment serum levels of soluble programmed cell death-ligand 1 predict prognosis in patients with hepatitis B-related hepatocellular carcinoma
Anti-programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) therapy has shown promise in tumor immunotherapy. Our objectives were to measure pre-treatment serum-soluble PD-L1 (sPD-L1) levels and...
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Article
Compressibility of natural schreibersite up to 50 GPa
Schreibersite-(Fe, Ni)3P is a common accessory of iron meteorites, which carry direct information of planetary cores. Herein, in situ synchrotron-radiation X-ray diffraction (XRD) experiments of a natural single-...
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Article
Open Accessp-Hydroxylcinnamaldehyde induces the differentiation of oesophageal carcinoma cells via the cAMP-RhoA-MAPK signalling pathway
p-Hydroxylcinnamaldehyde (CMSP) has been identified as an inhibitor of the growth of various cancer cells. However, its function in oesophageal squamous cell carcinoma (ESCC) and the underlying mechanism remai...
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Article
Quadratic nonconforming finite element method for 3D Stokes equations on cuboid meshes
In this paper, the quadratic nonconforming brick element (MSLK element) introduced in [10] is used for the 3D Stokes equations. The instability for the mixed element pair MSLK−P 1 ...
