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Article
Bone age assessment based on different MRI modalities of the proximal humerus epiphysis: the comparisons of T1WI, T2WI, and PDWI
Bone age assessment (BAA) is crucial in various fields, including legal proceedings, athletic competitions, and clinical medicine. However, the use of X-ray methods for age estimation without medical indicatio...
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Article
GLGFormer: Global Local Guidance Network for Mucosal Lesion Segmentation in Gastrointestinal Endoscopy Images
Automatic mucosal lesion segmentation is a critical component in computer-aided clinical support systems for endoscopic image analysis. Image segmentation networks currently rely mainly on convolutional neural...
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Article
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1
Bladder outlet obstruction (BOO) results in significant fibrosis in the chronic stage and elevated bladder pressure. Piezo1 is a type of mechanosensitive (MS) channel that directly responds to mechanical stimu...
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Article
Influence of pier height on the safety of trains running on high-speed railway bridges during earthquakes
Sudden earthquakes pose a threat to the running safety of trains on high-speed railway bridges, and the stiffness of piers is one of the factors affecting the dynamic response of train-track-bridge system. In ...
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Effect of distance between heat sources on droplet transfer behavior and weld formation of AH36 during laser and CWW GMAW arc hybrid welding
In order to analyze the influence of the distance between heat sources (DLA) on the welding process, the effects of DLA on the droplet transfer behavior, weld formation characteristics and weld formation mechanis...
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Article
Comprehensive Glycosylation Characterization of Recombinant Human Erythropoietin by Electron-Activated Dissociation Mass Spectrometry
Recombinant human erythropoietin (rhEPO) is a glycoprotein that acts as the main hormone involved in regulating red blood cell production to treat anemia caused by chronic kidney disease or chemotherapy, which...
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Article
Three stilbenes from pigeon pea with promising anti-methicillin-resistant Staphylococcus aureus biofilm formation activity
Cajaninstilbene acid (CSA), longistylin A (LLA), and longistylin C (LLC) are three characteristic stilbenes isolated from pigeon pea. The objective of this study was to evaluate the antibacterial activity of t...
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Article
Correlation of Differentially Expressed lncRNAs with Intestinal Flora Imbalance, Small Intestinal Permeability, and Glucose Uptake in T2DM Mice
Diabetes is a major global health concern. This study aimed to investigate the correlation between differentially expressed lncRNAs in mice with type 2 diabetes mellitus (T2DM) and alterations in the intestina...
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Article
Open AccessInvestigating the in vitro antibacterial efficacy of composite bone cement incorporating natural product-based monomers and gentamicin
The objective of this study is to investigate the impact of four natural product extracts, namely, aloe-emodin, quercetin, curcumin, and tannic acid, on the in vitro bacteriostatic properties and biocompatibil...
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Article
Characterization of Adeno-Associated Virus Capsid Proteins by Microflow Liquid Chromatography Coupled with Mass Spectrometry
Adeno-associated virus (AAV) has been widely used to treat various human diseases as an important delivery vector for gene therapy due to its low immunogenicity and safety. AAV capsids proteins are comprised o...
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Article
Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115
STING (also known as MITA) is an adaptor protein that mediates cytoplasmic DNA-triggered signaling, and aberrant activation of STING/MITA by cytosolic self-DNA or gain-of-function mutations causes severe infla...
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Article
Colchicine Inhibits NETs and Alleviates Cardiac Remodeling after Acute Myocardial Infarction
Colchicine, a multipotent anti-inflammatory drug, has been reported to alleviate cardiac remodeling and improve cardiac function after acute myocardial infarction (AMI). However, the underlying mechanism remai...
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Article
Effect of preform structure on mechanical and thermal properties of SiCf/SiC composites
In this paper, SiCf/SiC composites with three kinds of preform structures, namely 2D multilayered, 3D angle-interlock and multiaxis 3D braided, were prepared by chemical vapor infiltration. The influences of pref...
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Chapter and Conference Paper
Feasibility Analysis on Optimization and Expansion of Ultra-Deep Well Casing Program in Fuman Oilfield
With the continuous deepening of exploration and development for Fuman oilfield, the existing casing program fails to effectively deal with downhole problems such as “overflow, leakage and collapse” caused by ...
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Chapter and Conference Paper
Evaluation of Gas Injection Capacity of Gas Injection Wells in Reservoir-Type Gas Storage
In view of the problems of large error and lack of theoretical basis in the conventional evaluation methods for the gas injection capacity of gas injection wells in reservoir-type gas storage, under the condit...
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Article
Correlation of glymphatic system abnormalities with Parkinson’s disease progression: a clinical study based on non-invasive fMRI
The glymphatic system is reportedly involved in Parkinson’s disease (PD). Based on previous studies, we aimed to confirm the correlation between the glymphatic system and PD progression by combining two imagin...
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Article
Open AccessAdvances in nuclear detection and readout techniques
“A Craftsman Must Sharpen His Tools to Do His Job,” said Confucius. Nuclear detection and readout techniques are the foundation of particle physics, nuclear physics, and particle astrophysics to reveal the nat...
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Article
Open AccessBuilding bridges of excellence: a comprehensive competence framework for nurses in hospice and palliative care—a mixed method study
Hospice and Palliative Care (HPC) is in high demand in China; however, the country is facing the shortage of qualified HPC nurses. A well-suited competence framework is needed to promote HPC human resource dev...
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Article
Open AccessVariable phenotypes and outcomes associated with the MMACHC c.482G > A mutation: follow-up in a large CblC disease cohort
The aim of this study was to characterize the variable phenotypes and outcomes associated with the methylmalonic aciduria and homocystinuria type C protein gene (MMACHC) c.482G > A mutation in 195 Chinese cases w...
