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Article
Open AccessIncreased risk of knee osteoarthritis in patients using oral N-acetylcysteine: a nationwide cohort study
Knee osteoarthritis (OA) is known to be a progressive degenerative disorder; however, recent evidence suggests that inflammatory mediators contribute to cartilage degradation. Studies have reported that N-acet...
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Article
Open AccessCorrelation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL
Wnt signaling plays an important role in development and maintenance of many organs and tissues. The most-studied secreted Wnt inhibitors are sclerostin (SOST), Dickkopf-related protein 1 (DKK-1), and secreted...
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Article
Open AccessHigh glucose concentration up-regulates the expression of matrix metalloproteinase-9 and -13 in tendon cells
Diabetes mellitus is associated with tendinopathy or tendon injuries. However, the mechanism underlying diabetic tendinopathy is unclear. The purpose of this study was to examine the effects of high glucose co...