1,008 Result(s)
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Article
Psychological Resilience Mediates the Association Between Childhood Maltreatment and Self-Harm Phenotype in Chinese Early Adolescents
Self-harm (SH) increases significantly in early adolescence with great variability, and childhood maltreatment (CM) contributes to this increase. Understanding the developmental pathway from CM to SH could pro...
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Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer’s Disease
Neuroinflammation and endothelial cell apoptosis are prominent features of blood–brain barrier (BBB) disruption, which have been described in Alzheimer’s disease (AD) and can predict cognitive decline. Recent ...
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Open AccessSearch for the \( {B}_s^0 \) → μ+μ−γ decay
A search for the fully reconstructed B s 0 ...
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Open AccessN6-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor
The potential involvement of circular RNAs (circRNAs) and N6-methyladenosine (m6A) modification in the progression of Wilms tumor (WT) has not been fully elucidated. This study investigates the regulatory mechani...
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Open AccessA positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression
The aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the development of various human cancers by modifying diverse biological functions. However, the precise molecular mechani...
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Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
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Article
PDE3B regulates KRT6B and increases the sensitivity of bladder cancer cells to copper ionophores
Cuproptosis is a new Cu-dependent programmed cell death manner that has shown regulatory functions in many tumor types, however, its mechanism in bladder cancer remains unclear. Here, we reveal that Phosphodie...
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Open AccessSearch for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...
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Article
Open AccessValuating the efficiency of social security and healthcare in OECD countries from a sustainable development
Under the goal of sustainable development, co** with the increase in social security and healthcare expenses caused by population aging is becoming increasingly important, but it is rare in the literature to...
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Open AccessBrain effect mechanism of lever positioning manipulation on LDH analgesia based on multimodal MRI: a study protocol
The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Lever Positioning Manipulation (LPM), which is closely linked to the brain's pain-regulating mechanisms. Magnetic Re...
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Open AccessEffects of factors from practical workpieces on ultrasonic LCR method stress measurement
The non-destructive stress measurement method is the main trend in residual stress analysis. The ultrasonic method, which utilizes the acoustoelastic effect of the longitudinal critically refracted (LCR) wave,...
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Article
Open AccessAmplitude analysis of the \( {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma \) decay
The resonant structure of the radiative decay Λ b 0 ...
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Synergistic rare-earth yttrium single atoms and copper phosphide nanoparticles for high-selectivity ammonia electrosynthesis
Electrochemical nitrate reduction to NH3 holds a great promise for N-upcycling in nature, while its sluggish reaction kinetics involved in both the stepwise deoxygenation and hydrogenation processes necessitates ...
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Open AccessRegulation of primary cilia disassembly through HUWE1-mediated TTBK2 degradation plays a crucial role in cerebellar development and medulloblastoma growth
Development of the cerebellum requires precise regulation of granule neuron progenitor (GNP) proliferation. Although it is known that primary cilia are necessary to support GNP proliferation, the exact molecul...
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Article
THBru attenuates diabetic cardiomyopathy by inhibiting RAGE-dependent inflammation
Diabetic cardiomyopathy (DCM) is a complication of diabetes mellitus characterized by heart failure and cardiac remodeling. Previous studies show that tetrahydroberberrubine (THBru) retrogrades cardiac aging b...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Open AccessPR-SET7 epigenetically restrains uterine interferon response and cell death governing proper postnatal stromal development
The differentiation of the stroma is a hallmark event during postnatal uterine development. However, the spatiotemporal changes that occur during this process and the underlying regulatory mechanisms remain el...
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Open AccessGenerative learning facilitated discovery of high-entropy ceramic dielectrics for capacitive energy storage
Dielectric capacitors offer great potential for advanced electronics due to their high power densities, but their energy density still needs to be further improved. High-entropy strategy has emerged as an effe...
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Open AccessSingle-cell and spatial transcriptomics reveal a high glycolysis B cell and tumor-associated macrophages cluster correlated with poor prognosis and exhausted immune microenvironment in diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignancy characterized by varied responses to treatment and prognoses. Understanding the metabolic characteristics driving DLBCL progression is crucia...
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Geometric Error Measurement of Rotary Axes on Five-Axis Machine Tools: A Review
For achieving high precision and effectiveness in five-axis computer numerical control (CNC) machine tools, the geometrical accuracy of the rotary axes is a crucial performance criterion. Furthermore, recent a...