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6,636 Result(s)
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Open AccessPyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
Fulminant hepatitis (FH) is a life-threatening clinical liver syndrome characterized by substantial hepatocyte necrosis and severe liver damage. FH is typically associated with severe oxidative stress, inflamm...
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Open AccessMiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification
Female infertility due to declining oocyte quality with age remains a significant challenge for patients and physicians, despite extensive research efforts. Recent studies suggest that microRNAs (miRNAs), whic...
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Open AccessEffect of temperature on tribofilm growth and the lubrication of the piston ring-cylinder liner system in two-stroke marine engines
This study is an optimized extension based on the authors’ previous research on the tribo-chemical reaction under constant temperature field of two-stroke internal combustion engines (ICEs). It establishes a c...
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Open AccessEffects of different afforestation years on soil moisture and nutrient content in Maxian Mountain of the Loess Plateau
In the area of “returning farmland to forest” on the Loess Plateau in China, it is difficult to cultivate artificially planted trees into forests. In the current study, abandoned cultivated land after 10 years...
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Open AccessModel based on the automated AI-driven CT quantification is effective for the diagnosis of refractory Mycoplasma pneumoniae pneumonia
The prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP) remains a clinically significant challenge. This study aimed to develop an early predictive model utilizing artificial intelligence (AI)-deri...
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Open AccessChildhood intra- and extra-familial maltreatment and later-life trajectories of depressive symptoms: evidence from China
Both late-life depression and childhood maltreatment have become major global public health issues, given their prevalence and social-economic and health consequences. However, previous studies have solely foc...
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Open AccessMacrophage membrane-reversibly camouflaged nanotherapeutics accelerate fracture healing by fostering MSCs recruitment and osteogenic differentiation
The fracture healing outcome is largely dependent on the quantities as well as osteogenic differentiation capacities of mesenchymal stem cells (MSCs) at the lesion site. Herein, macrophage membrane (MM)-revers...
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Open AccessHierarchical adaptive evolution framework for privacy-preserving data publishing
The growing need for data publication and the escalating concerns regarding data privacy have led to a surge in interest in Privacy-Preserving Data Publishing (PPDP) across research, industry, and government s...
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Open AccessDevelopment and internal validation of a model for predicting cefoperazone/sulbactam-associated coagulation disorders in Chinese inpatients
The use of cefoperazone/sulbactam (CPZ/SAM) could commonly cause vitamin K-dependent coagulation disorders and even hemorrhage sometimes. However, there is a lack of prediction tools estimating the risk for th...
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Open AccessCorrection: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy
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Open AccessActive learning streamlines development of high performance catalysts for higher alcohol synthesis
Develo** efficient catalysts for syngas-based higher alcohol synthesis (HAS) remains a formidable research challenge. The chain growth and CO insertion requirements demand multicomponent materials, whose com...
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Open AccessEpidemiological trends of subarachnoid hemorrhage at global, regional, and national level: a trend analysis study from 1990 to 2021
Subarachnoid hemorrhage (SAH) is a subtype of hemorrhagic stroke characterized by high mortality and low rates of full recovery. This study aimed to investigate the epidemiological characteristics of SAH betwe...
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Open AccessMeasurement of e+e− → ωη′ cross sections at \( \sqrt{s} \) = 2.000 to 3.080 GeV
We measured the Born cross sections for the process e+e− → ωη′ at 22 center-of-mass energies from 2.000 to 3.080 GeV with the BESIII detector at the BEPCII collider. We observed a resonant structure with a statis...
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Open AccessRelationship between social participation and depressive symptoms in patients with multimorbidity: the chained mediating role of cognitive function and activities of daily living
The potential mechanisms linking social participation and depressive symptoms in Chinese individuals with multimorbidity are not yet fully understood. This study aims to explore how cognitive function and acti...
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Open AccessTranscriptome sequencing of garlic reveals key genes related to the heat stress response
With global warming, heat stress has become an important factor that seriously affects crop yield and quality. Therefore, understanding plant responses to heat stress is important for agricultural practice, bu...
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Open Access“Multidisciplinary fast-track” care can significantly reduce risk of mortality among hip fracture patients at least 80 years old: a single-center retrospective study
“Multidisciplinary fast-track” (MFT) care can accelerate recovery and improve prognosis after surgery, but whether it is effective in older people after hip fracture surgery is unclear.
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Open AccessRibonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and metabolite homeostasis
Antimicrobial proteins contribute to host-microbiota interactions and are associated with inflammatory bowel disease (IBD), but our understanding on antimicrobial protein diversity and functions remains incomp...
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Publisher Correction: Characterizing the phenotypic and genetic structure of psychopathology in UK Biobank
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Open AccessLetter to the Editor: “Continuous use of metformin in patients receiving contrast medium: What is the evidence? A systematic review and meta-analysis”
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Open AccessA systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China
Canine enteric coronavirus (CECoV) is a prevalent infectious disease among dogs worldwide, yet its epidemiology in mainland China remains poorly understood. This systematic review and meta-analysis aimed to as...