6,681 Result(s)

Article

Correction: The functional diversity of plants dispersed via three upland rivers in humid subtropical monsoon climate

Rongyan Qian, Fu Cai, Yi Wen, María D. Bejarano, Shan Wu, Qin Yang… in Hydrobiologia (2024)

Article

Comparative proteomics in tall fescue to reveal underlying mechanisms for improving Photosystem II thermotolerance during heat stress memory

The escalating impacts of global warming intensify the detrimental effects of heat stress on crop growth and yield. Among the earliest and most vulnerable sites of damage is Photosystem II (PSII). Plants expos...

Guangyang Wang, **ulei Wang, Dongli Li, Xuehe Yang, Tao Hu, **min Fu in BMC Genomics (2024)

Article

IDH1-mutant metabolite D-2-hydroxyglutarate inhibits proliferation and sensitizes glioma to temozolomide via down-regulating ITGB4/PI3K/AKT

The heterogeneous molecular subtypes of gliomas demonstrate varied responses to chemotherapy and distinct prognostic outcomes. Gliomas with Isocitrate dehydrogenase 1 (IDH1) mutation are associated with better...

Shuangmei Tong, Jian Wu, Yun Song, Wenhuan Fu, Yifan Yuan… in Cell Death Discovery (2024)

Article

New mechanistic understanding of osteoclast differentiation and bone resorption mediated by P2X7 receptors and PI3K-Akt-GSK3β signaling

Osteoporosis is a global health issue characterized by decreased bone mass and microstructural degradation, leading to an increased risk of fractures. This study aims to explore the molecular mechanism by whic...

Jiajia Lu, **aojian Shi, Qiang Fu, Yaguang Han… in Cellular & Molecular Biology Letters (2024)

Article

Combined analysis of the metabolome and transcriptome reveals the metabolic characteristics and candidate genes involved in alkaloid metabolism in Heuchera micrantha Douglas ex Lindl

Alkaloids, important secondary metabolites produced by plants, play a crucial role in responding to environmental stress. Heuchera micrantha, a well-known plant used in landsca**, has the ability to purify air,...

Weichang Gong, Lina **ong, Hongbo Fu in BMC Plant Biology (2024)

Article

Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity and immune evasion in lower grade glioma

The expression dysregulation of microRNAs (miRNA) has been widely reported during cancer development, however, the underling mechanism remains largely unanswered. In the present work, we performed a systematic...

Zhen Yang, **aocen Liu, Hao Xu, Andrew E. Teschendorff… in Communications Biology (2024)

Article

Systematic comparison of sequencing-based spatial transcriptomic methods

Recent developments of sequencing-based spatial transcriptomics (sST) have catalyzed important advancements by facilitating transcriptome-scale spatial gene expression measurement. Despite this progress, effor...

Yue You, Yuting Fu, Lanxiang Li, Zhongmin Zhang, Shikai Jia, Shihong Lu… in Nature Methods (2024)

Article

WTAP/IGF2BP3-mediated GBE1 expression accelerates the proliferation and enhances stemness in pancreatic cancer cells via upregulating c-Myc

Pancreatic cancer (PC) is one of the most malignant cancers with highly aggressiveness and poor prognosis. N6-methyladenosine (m6A) have been indicated to be involved in PC development. Glucan Branching Enzyme...

Weiwei **, Yanru Yao, Yuhan Fu, **angxiang Lei… in Cellular & Molecular Biology Letters (2024)

Article

Genetic diversity and population structure of wheat landraces in Southern Winter Wheat Region of China

Wheat landraces are considered a valuable source of genetic diversity for breeding programs. It is useful to evaluate the genetic diversity in breeding studies such as marker-assisted selection (MAS), genome-w...

Ying Liu, Bisheng Fu, Qiaofeng Zhang, ** Cai, Wei Guo, Wenling Zhai… in BMC Genomics (2024)

Article

Genome-wide identification and molecular evolution of Dof transcription factors in Cyperus esculentus

Dof transcription factor family in Cyperus esculentus genome was identified and analyzed using bioinformatics. The analysis results revealed that C.esculentus genome contains 29 Dof genes (CesDof), all of which a...

Chun Fu, ZiHui Liao, Na Jiang, YaoJun Yang in BMC Genomics (2024)

Article

Plac8-ERK pathway modulation of monocyte function in sepsis

Sepsis, a life-threatening condition caused by infection, is characterized by the dysregulation of immune responses and activation of monocytes. Plac8, a protein, has been implicated in various inflammatory co...

Teng Zhang, **g-nan Fu, Gui-bing Chen, **u Zhang in Cell Death Discovery (2024)

Article

Correction: Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis

Chao Lu, Pengyun Qiao, Ruihai Fu, Yadi Wang, Jiayi Lu, ** Ling… in Cell Death & Disease (2024)

Article

Correction: Sorcin regulate pyroptosis by interacting with NLRP3 inflammasomes to facilitate the progression of hepatocellular carcinoma

Zhenfen Li, Ziyue Yang, Yuanyuan Zhu, Chunmeng Fu, Ning Li… in Cell Death & Disease (2024)