1,131 Result(s)
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Article
A non-invasive artificial intelligence model for identifying axillary pathological complete response to neoadjuvant chemotherapy in breast cancer: a secondary analysis to multicenter clinical trial
This study aims to develop a stacking model for accurately predicting axillary lymph node (ALN) response to neoadjuvant chemotherapy (NAC) using longitudinal MRI in breast cancer.
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Article
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening
Icariin (ICA) has a good neuroprotective effect and can upregulate neuronal basal autophagy in naturally aging rats. Mitochondrial dysfunction is associated with brain aging-related neurodegenerative diseases....
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Hermite Expansion Technique for Model Reduction of Circuit Systems with Delay Components
Model order reduction technique provides an effective way to reduce computational complexity in large-scale circuit simulations. This paper proposes a new model order reduction method for delay circuit systems...
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Open AccessA multicenter prospective study on the management of hepatoblastoma in children: a report from the Chinese Children’s Cancer Group
This study aimed to identify survival risk factors in Chinese children with hepatoblastoma (HB) and assess the effectiveness of the new treatment protocol proposed by the Chinese Children’s Cancer Group (CCCG)...
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Antitumor Effect of Apcin on Endometrial Carcinoma via p21-Mediated Cell Cycle Arrest and Apoptosis
Endometrial carcinoma (EC) is a prevalent gynecological malignancy characterized by increasing incidence and mortality rates. This underscores the critical need for novel therapeutic targets. One such potentia...
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Multiparameter Numerical Investigation of Two Types of Moving Interactions Between the Deep-Sea Mining Vehicle Track Plate and Seabed Soil: Digging and Rotating Motions
To ensure the safe performance of deep-sea mining vehicles (DSMVs), it is necessary to study the mechanical characteristics of the interaction between the seabed soil and the track plate. The rotation and digg...
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Article
Improved Initial Alignment Algorithm of SINS on Shaking Base Based on Kalman Filter
In the initial alignment of shaking base, Kalman filter is easy to diverge, and the alignment result is poor. Many scholars introduce various nonlinear filtering methods to solve this problem, but these filter...
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Interaction between ozone and paternal smoking on fetal congenital heart defects among pregnant women at high risk: a multicenter maternal–fetal medicine study
Evidence remains limited on the association between maternal ozone (O3) exposure and congenital heart defects (CHDs) in offspring, and few studies have investigated the interaction and modification of paternal sm...
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Article
Association between Serum Ferritin Levels and Metabolic-associated Fatty Liver Disease in Adults: a Cross-sectional Study Based on the NHANES
Ferritin, initially acting as an iron-storage protein, was found to be associated with metabolic diseases. Our study was designed to investigate the association between serum ferritin and metabolic-associated ...
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Article
Open AccessA portable transistor immunosensor for fast identification of porcine epidemic diarrhea virus
Widespread distribution of porcine epidemic diarrhea virus (PEDV) has led to catastrophic losses to the global pig farming industry. As a result, there is an urgent need for rapid, sensitive and accurate tests...
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Open AccessInterleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells
Dysregulation of immune surveillance is tightly linked to the development of metabolic dysfunction-associated steatohepatitis (MASH)-driven hepatocellular carcinoma (HCC); however, its underlying mechanisms re...
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Hybrid origin and hybrid status of the endangered Ilex sanqingshanensis revealed by molecular and morphological evidence
Identification of natural hybrids considered as endangered species is of vital importance in taxonomy and biodiversity conservation, as natural hybrids will usually waste the conservation resource and efforts....
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Article
FPGA-based position reconstruction method for neutron beam flux spatial distribution measurement in BNCT
A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy (BNCT) is being developed based on the two-dimensional Micromegas detector. To address the issue of l...
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Article
High Speed Sintering: Assessing the Influence of Energy Input on Microstructure and Mechanical Properties of Polyether Block Amide (PEBA) Parts
High speed sintering, a new powder-bed fusion additive manufacturing technology, utilizes infrared lights (IR) to intensely heat and melt polymer powders. The presence of defects such as porosity, which is ass...
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CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice
Podocyte lipotoxicity mediated by impaired cellular cholesterol efflux plays a crucial role in the development of diabetic kidney disease (DKD), and the identification of potential therapeutic targets that reg...
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Article
FOXP4-AS1 promotes CD8+ T cell exhaustion and esophageal cancer immune escape through USP10-stabilized PD-L1
Esophageal cancer (EC) is the 9th most frequently diagnosed malignancy globally with unfavorable prognosis. Immune escape is one of the principal factors leading to poor survival, however, the mechanism underl...
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Article
Open AccessNew method for calculating the windward area of irregular fragments
Average windward area is an important index for calculating the trajectory, velocity attenuation and terminal effect of explosive fragments. In order to solve the problems that existing theoretical method cann...
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Open AccessComparison of the clinical outcomes between proximal femoral nail anti-rotation with cement enhancement and hemiarthroplasty among elderly osteoporotic patients with intertrochanteric fracture
The proximal femoral nail anti-rotation (PFNA) with cement enhancement enhances the anchorage ability of internal fixation in elderly with osteoporotic intertrochanteric fracture. However, whether it is superi...
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Single-track geometrical characteristics under different energy input and mass addition in coaxial laser cladding
To provide a broad processing window with a high deposition rate, a comprehensive analysis of single-track geometrical characteristics over a wide range of laser energies and mass inputs in laser cladding is n...
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Article
Enantioselective synthesis of β- and α-amino ketones through reversible alkane carbonylation
The direct incorporation of alkanes and CO into value-added chiral products through alkane carbonylation is a desirable transformation; however, it remains inefficient. The carbonylation of alkanes via photoir...