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Article
Role of NRP-1 in VEGF-VEGFR2-Independent Tumorigenesis
Recent studies suggest that neuropilin-1 (NRP-1) promotes angiogenesis mainly via VEGF and its receptors. It promotes tumorigenesis via formation of the NRP-1/ VEGF (vascular endothelial growth factor)/VEGFR2 ...
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Article
Open AccessCirculating cell-free DNA-based methylation patterns for breast cancer diagnosis
Mammography is used to detect breast cancer (BC), but its sensitivity is limited, especially for dense breasts. Circulating cell-free DNA (cfDNA) methylation tests is expected to compensate for the deficiency ...
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Article
NDRG1 facilitates self-renewal of liver cancer stem cells by preventing EpCAM ubiquitination
Portal vein tumour thrombus (PVTT) is the main pathway of HCC intrahepatic metastasis and is responsible for the poor prognosis of patients with HCC. However, the molecular mechanisms underlying PVTT vascular ...