105 Result(s)
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Article
In Vitro Antimicrobial Activity of Benzoquinolinediones
The in vitro antibacterial and anti-fungal activity of benz[g]isoquinoline-5,10-dione (1), benzo[g]quinoline-5, 10-dione (2), benzo[g]quinoline-5,6-dione (3), and anthraquinone (4) was determined using the agar w...
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Chapter
Kinetically Specific Spin-Label Substrates of Liver Alcohol Dehydrogenase and of Liver Aldehyde Dehydrogenase
The metabolism of alcohol in the mammalian liver involves two enzymes: (i) alcohol dehydrogenase, which converts an alcohol to its corresponding aldehyde product through a readily reversible reaction, and (ii)...
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Article
GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells
The interleukin 7 receptor α-chain (IL-7Rα) is essential for T cell development in both humans and mice and for B cell development in mice. Whereas the transcription factor PU.1 regulates IL-7Rα expression in ...
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Chapter and Conference Paper
The Alcohol Detection Using Heart Rate Variability and Bioimpedance
In the study of physiological effect influenced by alcohol, the measurement of alcohol concentration is one important part of the researches. The efficient, accurate and convenient measurement tools are relati...
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Article
Effect of MDR1 gene polymorphism on progression of end-stage renal disease
P-glycoprotein is localized at the apical brush-border membrane of the proximal renal tubule and functions as extruding toxins and xenobiotics out of cells. The difference of P-glycoprotein's function resulted...
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Article
Incidental discovery of high systemic lupus erythematosus disease activity associated with cytomegalovirus viral activity
We try to find the association of cytomegalovirus (CMV) infection and anti-β2 glycoprotein 1 autoantibodies (anti-β2 GP1), a key antibody in antiphospholipid syndrome (APS), among systemic lupus erythematosus ...
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Article
Modified biplanar open-wedge high tibial osteotomy with rigid locking plate to treat varus knee
To introduce and characterize the modified biplanar opening high tibial osteotomy with rigid fixation to treat varus knee in young and active patients.
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Article
Open AccessIdentifying significant genetic regulatory networks in the prostate cancer from microarray data based on transcription factor analysis and conditional independency
Prostate cancer is a world wide leading cancer and it is characterized by its aggressive metastasis. According to the clinical heterogeneity, prostate cancer displays different stages and grades related to the...
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Article
Plasma IL-17A Is Increased in New-Onset SLE Patients and Associated with Disease Activity
To investigate the role of interleukin-17A (IL-17A) and Th17 cell in the pathogenesis of systemic lupus erythematosus (SLE), we studied the plasma IL-17A and the expression of Th17 cell transcription factor RO...
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Article
RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells
A disintegrin and metalloproteinase 9 (ADAM9) is a type I transmembrane protein that has been associated with cancer development and metastases. Here, we show that ADAM9 is highly expressed in metastatic cance...
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Article
Open AccessIncreasing CD44+/CD24- tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis
Cancer cells are believed to arise primarily from stem cells. CD44+/CD24- have been identified as markers for human breast cancer stem cells. Although, HER2 is a well known breast cancer oncogene, the mechanisms ...
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Article
Spectroscopic Properties, Energy Transfer and Structural Analysis of Sr2CeO4:M+ and Sr2CeO4:Eu3+,M+ (M+ = Li+, Na+, K+)
The room-temperature luminescent emission characteristics of Sr2CeO4:M+ and Sr2CeO4:Eu3+,M+ (M+ = Li+, Na+, K+) have been investigated under UV excitation. By introducing appropriate alkali metal cations dopants ...
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Article
Open AccessHIF-1α effects on angiogenic potential in human small cell lung carcinoma
Hypoxia-inducible factor-1 alpha (HIF-1α) maybe an important regulatory factor for angiogenesis of small cell lung cancer (SCLC). Our study aimed to investigate the effect of HIF-1α on angiogenic potential of ...
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Article
Comparison of RFFIT tests with different standard sera and testing procedures
The World Health Organization (WHO) standard assay for determining antibody level is the rapid fluorescent focus inhibition test (RFFIT) and is used to determine the degree of immunity after vaccination agains...
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Article
Preparation and identification of anti-rabies virus monoclonal antibodies
To provide a foundation for the development of rapid and specific methods for the diagnosis of rabies virus infection, anti-rabies virus monoclonal antibodies were prepared and rabies virus nucleoprotein and h...
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Article
A new plastic surgical technique for adult congenital webbed penis
To introduce a novel surgical technique for correction of adult congenital webbed penis.
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Article
Open AccessExpression of ERBB3 binding protein 1 (EBP1) in salivary adenoid cystic carcinoma and its clinicopathological relevance
ERBB3 binding protein 1 (EBP1) gene transfer into human salivary adenoid cystic carcinoma cells has been shown to significantly inhibit cell proliferation and reduce tumor metastasis in mouse models. In the curre...
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Article
Real-time PCR method for the detection and quantification of Acanthamoeba species in various types of water samples
In this study, a quantitative real-time PCR was developed to detect and quantify Acanthamoeba spp. in various environmental water samples. The water samples were taken from watershed, water treatment plant, and t...
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Article
Recent advances in the study of testicular nuclear receptor 4
Testicular nuclear receptor 4 (TR4), also known as NR2C2 (nuclear receptor subfamily 2, group C, member 2), is a transcriptional factor and a member of the nuclear receptor family. TR4 was initially cloned fro...
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Article
Open AccessReproduction of hemangioma by infection with subgroup J avian leukosis virus: the vertical transmission is more hazardous than the horizontal way
Clinical cases of hemangioma associated with subgroup J avian leukosis virus (ALV-J) have been reported in commercial chicken layer flocks since 2006. We attempted to reproduce hemangioma through experimental ...