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  1. No Access

    Article

    In Vitro Antimicrobial Activity of Benzoquinolinediones

    The in vitro antibacterial and anti-fungal activity of benz[g]isoquinoline-5,10-dione (1), benzo[g]quinoline-5, 10-dione (2), benzo[g]quinoline-5,6-dione (3), and anthraquinone (4) was determined using the agar w...

    Alice M. Clark, Debra L. Huddleston, Cheng Yu Ma, Chuen-Huei Ho in Pharmaceutical Research (1984)

  2. No Access

    Chapter

    Kinetically Specific Spin-Label Substrates of Liver Alcohol Dehydrogenase and of Liver Aldehyde Dehydrogenase

    The metabolism of alcohol in the mammalian liver involves two enzymes: (i) alcohol dehydrogenase, which converts an alcohol to its corresponding aldehyde product through a readily reversible reaction, and (ii)...

    William E. Boisvert, Devkumar Mustafi in Enzymology and Molecular Biology of Carbon… (1993)

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    Article

    GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells

    The interleukin 7 receptor α-chain (IL-7Rα) is essential for T cell development in both humans and mice and for B cell development in mice. Whereas the transcription factor PU.1 regulates IL-7Rα expression in ...

    Hai-Hui Xue, Julie Bollenbacher, Valentina Rovella in Nature Immunology (2004)

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    Chapter and Conference Paper

    The Alcohol Detection Using Heart Rate Variability and Bioimpedance

    In the study of physiological effect influenced by alcohol, the measurement of alcohol concentration is one important part of the researches. The efficient, accurate and convenient measurement tools are relati...

    Chien-Hung Chen, Cheng-Yu Chen in 3rd Kuala Lumpur International Conference … (2007)

  5. Article

    Effect of MDR1 gene polymorphism on progression of end-stage renal disease

    P-glycoprotein is localized at the apical brush-border membrane of the proximal renal tubule and functions as extruding toxins and xenobiotics out of cells. The difference of P-glycoprotein's function resulted...

    Wei-xia Zhang, Bing Chen, Wen Zhang, Nan Chen, Zi-cheng Yu in Acta Pharmacologica Sinica (2007)

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    Article

    Incidental discovery of high systemic lupus erythematosus disease activity associated with cytomegalovirus viral activity

    We try to find the association of cytomegalovirus (CMV) infection and anti-β2 glycoprotein 1 autoantibodies (anti-β2 GP1), a key antibody in antiphospholipid syndrome (APS), among systemic lupus erythematosus ...

    Ben Yu-Jih Su, Cheng-Yu Su, Shan-Fu Yu in Medical Microbiology and Immunology (2007)

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    Article

    Modified biplanar open-wedge high tibial osteotomy with rigid locking plate to treat varus knee

    To introduce and characterize the modified biplanar opening high tibial osteotomy with rigid fixation to treat varus knee in young and active patients.

    Hai-ning Zhang, Jie Zhang, Cheng-yu Lv in Journal of Zhejiang University SCIENCE B (2009)

  8. Article

    Open Access

    Identifying significant genetic regulatory networks in the prostate cancer from microarray data based on transcription factor analysis and conditional independency

    Prostate cancer is a world wide leading cancer and it is characterized by its aggressive metastasis. According to the clinical heterogeneity, prostate cancer displays different stages and grades related to the...

    Hsiang-Yuan Yeh, Shih-Wu Cheng, Yu-Chun Lin, Cheng-Yu Yeh in BMC Medical Genomics (2009)

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    Article

    Plasma IL-17A Is Increased in New-Onset SLE Patients and Associated with Disease Activity

    To investigate the role of interleukin-17A (IL-17A) and Th17 cell in the pathogenesis of systemic lupus erythematosus (SLE), we studied the plasma IL-17A and the expression of Th17 cell transcription factor RO...

    **ao Qi Chen, Yan Cheng Yu, Hao Hua Deng, Jia Zhong Sun in Journal of Clinical Immunology (2010)

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    Article

    RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells

    A disintegrin and metalloproteinase 9 (ADAM9) is a type I transmembrane protein that has been associated with cancer development and metastases. Here, we show that ADAM9 is highly expressed in metastatic cance...

    Qin Xu, **uming Liu, Yili Cai, Youcheng Yu, Wantao Chen in Tumor Biology (2010)

  11. Article

    Open Access

    Increasing CD44+/CD24- tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis

    Cancer cells are believed to arise primarily from stem cells. CD44+/CD24- have been identified as markers for human breast cancer stem cells. Although, HER2 is a well known breast cancer oncogene, the mechanisms ...

    Kai-Hung Wang, An-Pei Kao, Chia-Cheng Chang, Jau-Nan Lee, Ming-Feng Hou in Molecular Cancer (2010)

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    Article

    Spectroscopic Properties, Energy Transfer and Structural Analysis of Sr2CeO4:M+ and Sr2CeO4:Eu3+,M+ (M+ = Li+, Na+, K+)

    The room-temperature luminescent emission characteristics of Sr2CeO4:M+ and Sr2CeO4:Eu3+,M+ (M+ = Li+, Na+, K+) have been investigated under UV excitation. By introducing appropriate alkali metal cations dopants ...

    Li-Li Shi, Cheng-Yu Li, Qiang Su in Journal of Fluorescence (2011)

  13. Article

    Open Access

    HIF-1α effects on angiogenic potential in human small cell lung carcinoma

    Hypoxia-inducible factor-1 alpha (HIF-1α) maybe an important regulatory factor for angiogenesis of small cell lung cancer (SCLC). Our study aimed to investigate the effect of HIF-1α on angiogenic potential of ...

    Jun Wan, Hui** Chai, Zaicheng Yu, Wei Ge in Journal of Experimental & Clinical Cancer … (2011)

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    Article

    Comparison of RFFIT tests with different standard sera and testing procedures

    The World Health Organization (WHO) standard assay for determining antibody level is the rapid fluorescent focus inhibition test (RFFIT) and is used to determine the degree of immunity after vaccination agains...

    Peng-cheng Yu, Akira Noguchi, Satoshi Inoue, Qing Tang, Simon Rayner in Virologica Sinica (2012)

  15. Article

    Preparation and identification of anti-rabies virus monoclonal antibodies

    To provide a foundation for the development of rapid and specific methods for the diagnosis of rabies virus infection, anti-rabies virus monoclonal antibodies were prepared and rabies virus nucleoprotein and h...

    Wen-juan Wang, **ong Li, Li-hua Wang, Hu Shan, Lei Cao, Peng-cheng Yu in Virologica Sinica (2012)

  16. No Access

    Article

    A new plastic surgical technique for adult congenital webbed penis

    To introduce a novel surgical technique for correction of adult congenital webbed penis.

    Yue-bing Chen, **an-fan Ding, Chong Luo in Journal of Zhejiang University SCIENCE B (2012)

  17. Article

    Open Access

    Expression of ERBB3 binding protein 1 (EBP1) in salivary adenoid cystic carcinoma and its clinicopathological relevance

    ERBB3 binding protein 1 (EBP1) gene transfer into human salivary adenoid cystic carcinoma cells has been shown to significantly inhibit cell proliferation and reduce tumor metastasis in mouse models. In the curre...

    Jian Sun, Yixi Luo, Zhen Tian, Liang Gu, Shu Chi **a, Youcheng Yu in BMC Cancer (2012)

  18. No Access

    Article

    Real-time PCR method for the detection and quantification of Acanthamoeba species in various types of water samples

    In this study, a quantitative real-time PCR was developed to detect and quantify Acanthamoeba spp. in various environmental water samples. The water samples were taken from watershed, water treatment plant, and t...

    Po-Min Kao, Min-Che Tung, Bing-Mu Hsu, Hsien-Lung Tsai in Parasitology Research (2013)

  19. No Access

    Article

    Recent advances in the study of testicular nuclear receptor 4

    Testicular nuclear receptor 4 (TR4), also known as NR2C2 (nuclear receptor subfamily 2, group C, member 2), is a transcriptional factor and a member of the nuclear receptor family. TR4 was initially cloned fro...

    **an-fan Ding, Shi-cheng Yu, Bi-de Chen in Journal of Zhejiang University SCIENCE B (2013)

  20. Article

    Open Access

    Reproduction of hemangioma by infection with subgroup J avian leukosis virus: the vertical transmission is more hazardous than the horizontal way

    Clinical cases of hemangioma associated with subgroup J avian leukosis virus (ALV-J) have been reported in commercial chicken layer flocks since 2006. We attempted to reproduce hemangioma through experimental ...

    Yan Lin, **g **a, Yang Zhao, Fuyan Wang, Songcheng Yu, Nianli Zou in Virology Journal (2013)

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