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126 Result(s)
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Article
Inhalable iron redox cycling powered nanoreactor for amplified ferroptosis-apoptosis synergetic therapy of lung cancer
Fenton reaction centered ferroptosis-apoptosis synergetic therapy has emerged as a promising tumor elimination strategy. However, the low intracellular Fenton level and accumulation of therapeutics at the lesi...
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Sugarcane ScOPR1 gene enhances plant disease resistance through the modulation of hormonal signaling pathways
Transgenic plants stably overexpressing ScOPR1 gene enhanced disease resistance by increasing the accumulation of JA, SA, and GST, as well as up-regulating the expression of genes related to signaling pathways.
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Article
Open AccessImproving the production of carbamoyltobramycin by an industrial Streptoalloteichus tenebrarius through metabolic engineering
Tobramycin is an essential and extensively used broad-spectrum aminoglycoside antibiotic obtained through alkaline hydrolysis of carbamoyltobramycin, one of the fermentation products of Streptoalloteichus tenebra...
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Article
Molten metal-organic complex to synthesize versatile ultrathin non-layered oxides
Two-dimensional (2D) materials have attracted a great deal of research interest because of their unique electrical, magnetic, optical, mechanical, and catalytic properties for various applications. To date, ho...
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The reformation of catalyst: From a trial-and-error synthesis to rational design
The appropriate catalysts can accelerate the reaction rate and effectively boost the efficient conversion of various molecules, which is of great importance in the study of chemistry, chemical industry, energy...
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Article
α-Cyanostilbene-based Molecule with the Synergistical Mechanisms of AIE, ESIPT and TICT: A New Schiff Base Probe for Selective Detection of Fe3+ and Reversible Response to HCl/NH3 Vapor
We designed and synthesized a new Schiff base probe, which incorporated the salicylaldehyde-analogue α-cyanostilbene and benzophenone hydrazone by the imine linkage. Its chemical structure was verified by FT-I...
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Article
XylR Overexpression in Escherichia coli Alleviated Transcriptional Repression by Arabinose and Enhanced Xylitol Bioproduction from Xylose Mother Liquor
Xylitol is a polyol widely used in food, pharmaceuticals, and light industries. It is currently produced through the chemical catalytic hydrogenation of xylose and generates xylose mother liquor as a substanti...
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Article
Open AccessDual peptides-modified cationic liposomes for enhanced Lung cancer gene therapy by a gap junction regulating strategy
Gene therapy for lung cancer has emerged as a novel tumor-combating strategy for its superior tumor specificity, low systematical toxicity and huge clinical translation potential. Especially, the applications ...
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Article
Stably doped graphene transparent electrode with improved light-extraction for efficient flexible organic light-emitting diodes
Graphene-based flexible transparent electrodes (FTEs) are promising candidate materials for develo** next-generation flexible organic light-emitting diodes (OLEDs). However, the quest for high-efficiency OLE...
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Article
Novel citrinin derivatives from fungus Penicillium sp. TW131-64 and their antimicrobial activities
Six new citrinin derivatives (1, 2, 4, 10, 11, and 16), along with fourteen known analogues, were acquired from Penicillium sp. TW131-64, a marine-derived fungus strain. The chemical structures of new compounds w...
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Article
Cardioprotective Role of Swertiamarin, a Plant Glycoside Against Experimentally Induced Myocardial Infarction via Antioxidant and Anti-inflammatory Functions
The study examined the protective effects of swertiamarin on rats with experimentally induced myocardial infarction. Three to six week-old male albino Wistar rats were used in this study and experimental myoca...
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Article
A molecular sieve-containing protective separator to suppress the shuttle effect of redox mediators in lithium-oxygen batteries
Lithium-oxygen (Li-O2) batteries have a great potential in energy storage and conversion due to their ultra-high theoretical specific energy, but their applications are hindered by sluggish redox reaction kinetic...
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Article
In Vivo and In Vitro Biocompatibility Study of CuS Nanoparticles: Photosensitizer for Glioblastoma Photothermal Therapy
Although photothermal treatment (PTT) has made significant progress in the fight against cancer, certain types of malignant tumors are still difficult to eradicate. PTT uses photothermal transforming agents to...
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Article
Oxidization-induced structural optimization of Ni3Fe-N-C derived from 3D covalent organic framework for high-efficiency and durable oxygen evolution reaction
NiFe composites have been regarded as promising candidates to replace commercial noble-based electrocatalysts for the oxygen evolution reaction (OER). However, their practical applications still suffer from po...
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Article
Solvent sieving separators implement dual electrolyte for high-voltage lithium-metal batteries
Lithium-metal batteries (LMBs) based on high-voltage cathodes would deliver high specific energy density to meet the demand of future energy storage. However, develo** liquid electrolytes with wide electroch...
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Article
A triple-enhanced chemodynamic approach based on glucose-powered hybrid nanoreactors for effective bacteria killing
Rapid evolution of multidrug resistance in bacterial pathogens is outpacing the development of new antibiotics, and chemodynamic therapy (CDT) provides an excellent alternative. However, achieving highly effic...
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Article
An oxygen reservoir-irrigated photoimmunotherapy of malignant melanoma
Tumor hypoxia is the pivotal factor limiting the therapeutic efficacy of photodynamic therapy (PDT), and can be partly improved by either the oxygen economizing or the oxygen supplementation strategies. Nevert...
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Article
A non-surgical suturing strategy for rapid cardiac hemostasis
As the central organ of the human body, once the heart is damaged, it will cause devastating damage to the circulation system of the whole body, often leading to rapid death. Currently, the only treatment opti...
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Dry Suspension Containing Coated Pellets with pH-Dependent Drug Release Behavior for the Taste-masking of Azithromycin
Azithromycin (AZI) is a commonly used antibiotic with extremely bitter taste that severely decreases the compliance of patients. Besides, the poor solubility of AZI in alkaline pH makes it difficult to be abso...
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Article
Progress on Pharmaceutical Sciences/Pharmacy Postgraduate Education: a Bibliometric Perspective
The study quantitatively investigated the related research progress in pharmaceutical sciences/pharmacy education from a bibliometric angle and provided feasible suggestions to facilitate the development of ph...