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    Article

    Sam68 promotes osteogenic differentiation of aortic valvular interstitial cells by TNF-α/STAT3/autophagy axis

    Calcified aortic valve disease (CAVD) is a major non-rheumatic heart valve disease in the world, with a high mortality rate and without suitable pharmaceutical therapy due to its complex mechanisms. Src-associ...

    **ng Liu, Qiang Zheng, Kan Wang, ****g Luo in Journal of Cell Communication and Signaling (2023)

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    Open Access

    TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1

    Cholesterol metabolism plays a critical role in the progression of hepatocellular carcinoma (HCC), but it is not clear how cholesterol metabolism is regulated. The tubulin beta class I genes (TUBBs) are associ...

    **aobo Wang, Jiawei Shi, Mingming Huang, Jiehong Chen, Jia Dan in Cell Death & Disease (2023)

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    Open Access

    Structural basis for neutralization of an anicteric hepatitis associated echovirus by a potent neutralizing antibody

    Rui Feng, Lei Wang, Dawei Shi, Binyang Zheng, Li Zhang, Hai Hou, Deju **a in Cell Discovery (2021)

  4. Article

    Open Access

    Effect of stem cell transplantation on patients with ischemic heart failure: a systematic review and meta-analysis of randomized controlled trials

    Stem cell transplantation (SCT) has become a promising way to treat ischemic heart failure (IHF). We performed a large-scale meta-analysis of randomized clinical trials to investigate the efficacy and safety o...

    Yixuan Wang, Fen Xu, **gwei Ma, Jiawei Shi, Si Chen in Stem Cell Research & Therapy (2019)

  5. Article

    Open Access

    Prolactin inhibits the progression of intervertebral disc degeneration through inactivation of the NF-κB pathway in rats

    Intervertebral disc degeneration (IVDD) is one of the key predisposing factors for low back pain. Although the exact mechanism remains unclear, inflammatory response and nucleus pulposus (NP) apoptosis are kno...

    **exing Wu, Yu Liu, **aobin Guo, Wei Zhou, Liangliang Wang in Cell Death & Disease (2018)

  6. Article

    Open Access

    Titanium particle-induced osteogenic inhibition and bone destruction are mediated by the GSK-3β/β-catenin signal pathway

    Wear debris-induced osteogenic inhibition and bone destruction are critical in the initiation of peri-prosthetic osteolysis. However, the molecular mechanism underlying this phenomenon is poorly understood. In...

    Ye Gu, Zhirong Wang, Jiawei Shi, Liangliang Wang, Zhenyang Hou in Cell Death & Disease (2017)

  7. Article

    A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo

    Sorting nexins (SNXs) are phosphoinositide-binding proteins implicated in the sorting of various membrane proteins in vitro, but the in vivo functions of them remain largely unknown. We reported previously that S...

    Yanqun Chen, Bin Wu, Liangliang Xu, Huapeng Li, Jianhong **a, Wenguang Yin in Cell Research (2012)