3,334 Result(s)
within
**aoyuan **a
-
Article
A semi-active quasi-zero-stiffness vibration isolation system through controllable lateral spring stiffness
In this work, a semi-active quasi-zero-stiffness (QZS) vibration isolation system with controllable lateral springs was proposed and its practical vibration isolation effectiveness was demonstrated through the...
-
Article
A fast DBSCAN algorithm using a bi-directional HNSW index structure for big data
The Density Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm is one of the most popular and effective density-based clustering algorithms at present. Although it can effectively identify ...
-
Article
Bioinspired Polarized Optical Flow Enables Turbid Underwater Target Motion Estimation
Underwater target motion estimation is a challenge for ocean military and scientific research. In this work, we propose a method based on the combination of polarization imaging and optical flow for turbid und...
-
Article
Microstructure Regulation and Combustion Performance Optimization of PVDF/Al Composite Powder by Non-covalent Functionalized Graphenes
Graphene prepared by non-covalent modification of sulfonated poly(ether-ether-ketone) (SPG) was combined with polyvinylidene fluoride(PVDF)/Al to improve the PVDF/Al thermal conductivity while reducing the eff...
-
Article
Solid-to-Solid Diffusion Bond Between SA508 Low Alloy Steel to 316L Stainless Steel by Hot Isostatic Pressing
Solid-to-solid diffusion bond between ferritic SA508 low alloy steel (LAS) and austenitic 316L stainless steel (SS) via hot isostatic pressing (HIP) was evaluated. This study investigated the microstructural a...
-
Article
Chinese guidelines on the management of ascites in cirrhosis
In 2023, Chinese Society of Hepatology of Chinese Medical Association convened a panel of experts to update the Chinese guidelines on the management of ascites and associated complications in cirrhosis which w...
-
Article
Open AccessDeep learning for multi-type infectious keratitis diagnosis: A nationwide, cross-sectional, multicenter study
The main cause of corneal blindness worldwide is keratitis, especially the infectious form caused by bacteria, fungi, viruses, and Acanthamoeba. The key to effective management of infectious keratitis hinges o...
-
Article
Open AccessDo global innovation networks influence the status of global value chains? Based on a patent cooperation network perspective
Under the impact of economic globalization, the internationalization of production and trade has given rise to global value chains (GVCs) and global innovation networks (GINs); however, few studies have explor...
-
Article
Open AccessSuppressing SENP1 inhibits esophageal squamous carcinoma cell growth via SIRT6 SUMOylation
Esophageal squamous cell carcinoma (ESCC) is a prevalent tumor in the gastrointestinal tract, but our understanding of the molecular mechanisms underlying ESCC remains incomplete. Existing studies indicate tha...
-
Article
Open AccessNeoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial
Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...
-
Article
Metabolic engineering of Escherichia coli to efficiently produce 3-deacyl-2-acyloxyacyl-4′-monophosphoryl-lipid A
3-O-Deacyl-2-O-palmitoyl-4′-monophosphoryl lipid A (MPL) has recently been used in vaccine adjuvant. In this study, an E. coli mutant WZM012 which can effectively produce MPL has been constructed from E. coli MG1...
-
Article
Optimization of evaluation method for low nitrogen tolerance in soybean germplasm seedlings
Nitrogen is a critical macro-nutrient for growth and development of soybeans (Glycine max L.). Improving nitrogen use efficiency and develo** low nitrogen tolerance varieties are important approaches to mitigat...
-
Article
Distinct palmitoylation of Foxp3 regulates the function of regulatory T cells via palmitoyltransferases
-
Article
Metabolic engineering of Corynebacterium glutamicum CGY-PG-304 for promoting gamma-aminobutyric acid production
Gamma-aminobutyric acid is a versatile and non-protein amino acid that plays a significant role in medicine, food, and cosmetics. The synthesis of gamma-aminobutyric acid is restricted by complex metabolic mec...
-
Article
Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013
Fibroblast activation protein (FAP) has emerged as a highly promising target for cancer diagnostic imaging and targeted radionuclide therapy. To exploit the therapeutic potential of suitably radiolabeled FAP i...
-
Article
A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis
DNA origami is capable of spatially organizing molecules into sophisticated geometric patterns with nanometric precision. Here we describe a reconfigurable, two-dimensional DNA origami with geometrically patte...
-
Article
Alkyl chain modulation of asymmetric hexacyclic fused acceptor synergistically with wide bandgap third component for high efficiency ternary organic solar cells
Herein, two asymmetric hexacyclic fused small molecule acceptors (SMAs), namely BP4F-HU and BP4F-UU, were synthesized. The elongated outside chains in the BP4F-UU molecule played a crucial role in optimizing t...
-
Article
Experimental study on magnetic ball-assisted magnetic abrasive finishing for irregular spherical internal cavity of waveguide formed by selective laser melting
In order to improve the surface roughness of the spherical internal cavity of the special-shaped waveguide which was formed by selective laser melting (SLM) and explore the influence of the main processing par...
-
Article
Open AccessThe role and application of small extracellular vesicles in glioma
Small extracellular vesicles (sEVs) are cell-derived, nanometer-sized particles enclosed by a lipid bilayer. All kinds of biological molecules, including proteins, DNA fragments, RNA, lipids, and metabolites, ...
-
Article
Open AccessLPA1 antagonist-derived LNPs deliver A20 mRNA and promote anti-fibrotic activities
Activated fibroblasts are major mediators of pulmonary fibrosis. Fibroblasts are generally found in the connective tissue but upon activation can generate excess extracellular matrix (ECM) in the lung intersti...
