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Article
Phantom study of a self-shielded X-ray bone age assessment instrument against scattered radiation in children
Hand-wrist radiography is the most common and accurate method for evaluating children’s bone age. To reduce the scattered radiation of radiosensitive organs in bone age assessment, we designed a small X-ray in...
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Article
Open AccessTherapeutic effect and study of human umbilical cord blood mononuclear cells in patients with ischaemic bowel disease
Ischaemic bowel disease (ICBD) is a group of intestinal ischaemia syndromes caused by various aetiologies of reduced intestinal blood flow or vascular occlusion. ICBD can present as abdominal pain, bloody stoo...
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Article
Open AccessMinimally invasive techniques for lateral maxillary sinus floor elevation: small lateral window and one-stage surgery—a 2–5-year retrospective study
This study aimed to introduce a minimally invasive technique for maxillary sinus floor elevation using the lateral approach (lSFE) and to determine the factors that influence the stability of the grafted area ...
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Article
A dynamic DNA tetrahedron framework for active targeting
An active targeting strategy-enabled DNA tetrahedron delivery vehicle could facilitate stable drug encapsulation and stimuli-responsive on-demand release, building a universal platform for different drug deliv...
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Article
Open AccessDownregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin signaling pathway
Diabetes-related osteoporosis (DOP) is a chronic disease caused by the high glucose environment that induces a metabolic disorder of osteocytes and osteoblast-associated mesenchymal stem cells. The processes o...
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Article
Trichostatin A inhibits dendritic cell maturation through down-regulating NF—κ B (p65) pathway
Recent evidence suggested that histone deacetylase inhibitor (HDACi) could inhibit dendritic cell (DC) maturation. However, the mechanism is unclear. Here, we aimed to study whether Trichostatin A (TSA), the m...
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Article
Open AccessHard tissue stability after guided bone regeneration: a comparison between digital titanium mesh and resorbable membrane
Guided bone regeneration (GBR) uses resorbable and non-resorbable membranes as biological barriers. This study compared the differences in hard tissue stability between GBR using evidence-based digital titaniu...
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Article
Open AccessJKAMP inhibits the osteogenic capacity of adipose-derived stem cells in diabetic osteoporosis by modulating the Wnt signaling pathway through intragenic DNA methylation
Diabetic osteoporosis (DOP) is a systemic metabolic bone disease caused by diabetes mellitus (DM). Adipose-derived stem cells (ASCs) play an important role in bone regeneration. Our previous study confirmed th...
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Article
Open AccessTitanium mesh for bone augmentation in oral implantology: current application and progress
Guided bone regeneration (GBR) is an effective and simple method for bone augmentation, which is often used to reconstruct the alveolar ridge when the bone defect occurs in the implant area. Titanium mesh has ...
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Article
Six long noncoding RNAs as potentially biomarkers involved in competitive endogenous RNA of hepatocellular carcinoma
To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded ...
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Article
Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment
Although organic nanomaterials and inorganic nanoparticles possess inherent flexibility, facilitating functional modification, increased intracellular uptake and controllable drug release, their underlying cyt...
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Article
Up-Regulation of SorCS1, an Important Sorting Receptor, in the Retina of a Form-Deprivation Rat Model
Visually guided regulation is a sophisticated and active process, whereby sensory input helps to shape ocular development. Here, we sought to investigate the potential involvement of SorCS1, an important prote...
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Article
Correction to: Bone Marrow Derived Pluripotent Cells are Pericytes which Contribute to Vascularization
Please note the following errors in the original version.
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Article
Intravenous miR-144 reduces left ventricular remodeling after myocardial infarction
MicroRNA-144 is a cytoprotective miRNA. Our previous study showed that miR-144 provides potent acute cardioprotection in an ischemia/reperfusion injury model. This study was performed to further assess whether...
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Article
Open AccessAngiogenesis in a 3D model containing adipose tissue stem cells and endothelial cells is mediated by canonical Wnt signaling
Adipose-derived stromal cells (ASCs) have gained great attention in regenerative medicine. Progress in our understanding of adult neovascularization further suggests the potential of ASCs in promoting vascular...
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Article
Open AccessInjectable and thermosensitive TGF-β1-loaded PCEC hydrogel system for in vivo cartilage repair
Chondral defects pose a great challenge for clinicians to manage owing to the limited capacity for self-healing. Various traditional approaches have been adopted for the repair of these defects with unsatisfac...
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Application of Stem Cells and the Factors Influence Their Differentiation in Cartilage Tissue Engineering
Articular cartilage is a unique tissue which contents only one cell type and lack the ability to heal spontaneously. Current treatment for cartilage defects include non-operative treatment, traditional operati...
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Chapter
Cellular Response to Surface Topography and Substrate Stiffness
Materials can dominate stem cell fate by chemical, biological, topographical and mechanical approaches. Cell feel the cues provided by biomaterial surfaces at both micrometer and nanometer scale, which leads t...
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Article
Open AccessLithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV
Neurons display genomic fragility and show fragmented DNA in pathological degeneration. A failure to repair DNA breaks may result in cell death or apoptosis. Lithium protects retinal neurocytes following nutri...
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Article
Open AccessCrosstalk between adipose-derived stem cells and chondrocytes: when growth factors matter
Adipose-derived stem cells (ASCs) and mesenchymal stem cells are promising for tissue repair because of their multilineage differentiation capacity. Our previous data confirmed that the implantation of mixed A...
