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  1. Article

    Open Access

    Histopathology Feature Mining and Association with Hyperspectral Imaging for the Detection of Squamous Neoplasia

    Hyperspectral imaging (HSI) is a noninvasive optical modality that holds promise for early detection of tongue lesions. Spectral signatures generated by HSI contain important diagnostic information that can be...

    Guolan Lu, Dongsheng Wang, Xulei Qin, Susan Muller, James V. Little in Scientific Reports (2019)

  2. Article

    Open Access

    Head and Neck Cancer Detection in Digitized Whole-Slide Histology Using Convolutional Neural Networks

    Primary management for head and neck cancers, including squamous cell carcinoma (SCC), involves surgical resection with negative cancer margins. Pathologists guide surgeons during these operations by detecting...

    Martin Halicek, Maysam Shahedi, James V. Little, Amy Y. Chen in Scientific Reports (2019)