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Article
New genes helped acorn barnacles adapt to a sessile lifestyle
Barnacles are the only sessile lineages among crustaceans, and their sessile life begins with the settlement of swimming larvae (cyprids) and the formation of protective shells. These processes are crucial for...
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Article
Single-atom iron boosts electrochemiluminescence for ultrasensitive carcinoembryonic antigen detection
A simple and ultrasensitive sandwich-type electrochemiluminescence (ECL) immunosensor has been developed using porous three-dimensional gold nanoparticles (Au NPs) iron(Fe)–zinc(Zn) metal–organic frameworks (A...
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Article
Open AccessInflammatory responses and barrier disruption in the trachea of chicks following Mycoplasma gallisepticum infection: a focus on the TNF-α-NF-κB/MLCK pathway
Mycoplasma gallisepticum (MG) can induce persistent inflammatory damage to the tracheal mucosa of poultry and cause chronic respiratory diseases in chickens. To further investigate the mechanism of MG-induced inj...
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Article
Somatic embryogenesis and plant regeneration of Litchi chinensis Sonn. cv. ‘Zili’ from immature zygotic embryos
In vitro plant regeneration is a powerful tool for the propagation and conservation of valuable plant species. Among the diverse range of techniques available, the induction of somatic embryos from immature zy...
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Article
Open AccessArtificial intelligence in glaucoma: opportunities, challenges, and future directions
Artificial intelligence (AI) has shown excellent diagnostic performance in detecting various complex problems related to many areas of healthcare including ophthalmology. AI diagnostic systems developed from f...
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Article
An overview of the mechanisms underlying hypoxia tolerance differences in aquatic animals and their inspirations for aquaculture
The decline in dissolved oxygen concentrations has been one of the most important changes occurring in the oceans, greatly impacting the survival, abundance, development, metabolism, growth, and reproduction o...
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Article
Open AccessThe effect of the Ankle Pump Exercise (APE) counter system assisted ankle pump motion in patients after femoral neck fracture
To explore the effect of the Ankle Pump Exercise (APE) counter system on moderate to high-risk Venous thromboembolism (VTE) after femoral neck fracture surgery.
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Article
Environmental Contamination and Health Risk Assessment to Toxic Elements in an Active Lead–Zinc Mining Area
Non-ferrous metal mining and smelting has emitted large amounts of associated toxic elements into the environment and poses potential health risks to human health. In this study, local residents’ and miner’s h...
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Article
Open AccessDevelopment of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1
Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natura...
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Article
Analysis of fracture propagation and shale gas production by intensive volume fracturing
This paper presents an integrated study from fracture propagation modeling to gas flow modeling and a correlation analysis to explore the key controlling factors of intensive volume fracturing. The fracture pr...
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Article
Open AccessReal-world outcomes of PD-L1 inhibitors combined with thoracic radiotherapy in the first-line treatment of extensive stage small cell lung cancer
The CREST study showed that the addition of thoracic radiotherapy (TRT) could improve the survival rate in patients with extensive stage small cell lung cancer (ES-SCLC), but whether TRT can bring survival ben...
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Article
Open AccessThe development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1
Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is eva...
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Article
Open AccessCorrection to: TIGIT blockade enhances tumor response to radiotherapy via a CD103 + dendritic cell-dependent mechanism
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Article
Open AccessClinical characteristics and outcome of dural arteriovenous fistulas secondary to cerebral venous sinus thrombosis: a primary or secondary event?
The Dural Arteriovenous Fistulas (DAVFs) secondary to cerebral venous sinus thrombosis (CVST) are rather rare. The aim of present study is to investigate the clinical and radiological features, and treatment o...
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Chapter and Conference Paper
Multi-scale Cross-restoration Framework for Electrocardiogram Anomaly Detection
Electrocardiogram (ECG) is a widely used diagnostic tool for detecting heart conditions. Rare cardiac diseases may be underdiagnosed using traditional ECG analysis, considering that no training dataset can exh...
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Article
Open AccessTIGIT blockade enhances tumor response to radiotherapy via a CD103 + dendritic cell-dependent mechanism
Blockade of the T cell immunoreceptor with the immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) can enhance innate and adaptive tumor immunity and radiotherapy (RT) can enhance ...
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Article
Efficacy and safety of immune checkpoint inhibitors plus anlotinib in small cell lung cancer with brain metastases: a retrospective, multicentre study
Previous studies showed that both immune checkpoint inhibitors (ICIs) and anlotinib have central nervous system (CNS) efficacy. This study aimed to evaluate the efficacy and safety of ICIs combined with anloti...
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Article
Open AccessAssessment of postpartum haemorrhage for placenta accreta: Is measurement of myometrium thickness and dark intraplacental bands using MRI helpful?
This study aimed to investigate the predictive values of magnetic resonance imaging (MRI) myometrial thickness grading and dark intraplacental band (DIB) volumetry for blood loss in patients with placenta accr...
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Article
Open AccessProphylactic cranial irradiation (PCI) versus active surveillance in patients with limited-stage small cell lung cancer: a retrospective, multicentre study
The recommendation of PCI for limited-stage small cell lung cancer (LS-SCLC) is primarily based on evidence from the pre-magnetic resonance imaging (MRI) era. However, as MRI accuracy improves and stereotactic...
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Article
Open AccessMagnetic resonance spectroscopy associations with clinicopathologic features of estrogen-dependent endometrial cancer
We studied the magnetic resonance spectroscopy (MRS) associations with clinicopathologic features of estrogen-dependent endometrial cancer (type I EC).
