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  1. Article

    Open Access

    Rapid detection of lung cancer based on serum Raman spectroscopy and a support vector machine: a case-control study

    Early screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated the feasibility of serum Raman spectroscopy for rapid lung cancer screen...

    Linfang Yan, Huiting Su, Jiafei Liu, **aozheng Wen, Huaichao Luo, Yu Yin in BMC Cancer (2024)

  2. Article

    Open Access

    Efficacy of salvage surgery versus re-irradiation for isolated regional lymph node recurrence in patients with nasopharyngeal carcinoma

    To compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma (irrNPC) who underwent surgery or re-irradiation treatment.

    Yuebing Chen, Yi** Huang, **aoqiang Chen, Zhiwei Chen, **ane Peng in BMC Cancer (2024)

  3. Article

    Open Access

    MYO5A overexpression promotes invasion and correlates with low lymphocyte infiltration in head and neck squamous carcinoma

    Head and neck squamous carcinoma (HNSC) poses a significant public health challenge due to its substantial morbidity. Nevertheless, despite advances in current treatments, the prognosis for HNSC remains unsati...

    Juanli **ng, Yanan Gu, Yichen Song, Qi Liu, Qian Chen, Peng Han, Zhen Shen in BMC Cancer (2023)

  4. Article

    Open Access

    Visualization of breast cancer-related protein synthesis from the perspective of bibliometric analysis

    Breast cancer, as a daunting global health threat, has driven an exponential growth in related research activity in recent decades. An area of research of paramount importance is protein synthesis, and the ana...

    Jiawei Xu, Chengdong Yu, **aoqiang Zeng in European Journal of Medical Research (2023)

  5. Article

    Open Access

    Exogenous hormone therapy and non-melanoma skin cancer (keratinocyte carcinoma) risk in women: a systematic review and meta-analysis

    Previous studies reported inconsistent results regarding the association between keratinocyte carcinoma (KC) and exogenous hormone therapy. This study aimed to investigate the association between the use of ex...

    Lin Li, Baoqiang Pei, Yanyan Feng in BMC Cancer (2023)

  6. Article

    Open Access

    Efficacy and safety of atezolizumab plus bevacizumab treatment for advanced hepatocellular carcinoma in the real world: a single-arm meta-analysis

    Atezolizumab plus bevacizumab was approved in 2020 as a first-line treatment for advanced hepatocellular carcinoma (HCC). The purpose of this study was to assess the curative effect and tolerability of the com...

    **aoqiang Gao, Rui Zhao, Huaxing Ma, Shi Zuo in BMC Cancer (2023)

  7. Article

    Open Access

    Excellent survival of pathological N0 small cell lung cancer patients following surgery

    Current clinical guidelines recommend surgery only for cT1-2N0M0 small cell lung cancer (SCLC) patients. In light of recent studies, the role of surgery in the treatment of SCLC needs to be reconsidered.

    Zichen Fu, Di Li, Chaoqiang Deng, **gshun Zhang in European Journal of Medical Research (2023)

  8. Article

    Open Access

    The ratio of monocytes to lymphocytes multiplying platelet predicts incidence of pulmonary infection-related acute kidney injury

    Inflammation is a crucial factor in the pathogenesis and development of acute kidney injury (AKI). Macrophages, as an important innate immune cell, regulate immune response and play a pathophysiological role i...

    Bo Shen, Zhou** Zou, Yang Li, ** Jia in European Journal of Medical Research (2022)

  9. Article

    Open Access

    Liver-specific lncRNA FAM99A may be a tumor suppressor and promising prognostic biomarker in hepatocellular carcinoma

    Increasing evidence shows that liver-specific long non-coding RNAs (lncRNAs) play important roles in the development of hepatocellular carcinoma (HCC). We identified a novel liver-specific lncRNA, FAM99A, and ...

    Meile Mo, **aoyun Ma, Yihuan Luo, Chao Tan, Bihu Liu, Peng Tang, Qian Liao in BMC Cancer (2022)

  10. Article

    Open Access

    The association of sex-biased ATRX mutation in female gastric cancer patients with enhanced immunotherapy-related anticancer immunity

    Genetic alterations have been proven to be the promising biomarkers for ICI response. However, sex biases in genetic alterations have been often ignored in the field of immunotherapy, which might specially inf...

    You Ge, Feiran Wei, Guo** Du, Gaoqiang Fei, Wei Li, **aoshan Li, **** Chu in BMC Cancer (2021)

  11. Article

    Open Access

    Eight-gene metabolic signature related with tumor-associated macrophages predicting overall survival for hepatocellular carcinoma

    In recent years, the relationship between tumor-associated macrophages (TAMs) and solid tumors has become a research hotspot. This study aims to explore the close relationship of TAMs with metabolic reprogramm...

    Junyu Huo, Liqun Wu, Yun** Zang, Hong**g Dong, **aoqiang Liu, Fu He in BMC Cancer (2021)

  12. Article

    Open Access

    Accuracy of multiparametric magnetic resonance imaging for diagnosing prostate Cancer: a systematic review and meta-analysis

    The application of multiparametric magnetic resonance imaging (mpMRI) for diagnosis of prostate cancer has been recommended by the European Association of Urology (EAU), National Comprehensive Cancer Network (...

    Liang Zhen, **aoqiang Liu, Chen Yegang, Yang Yongjiao, Xu Yawei, Kang Jiaqi in BMC Cancer (2019)

  13. Article

    Open Access

    Factors analysis on the use of key quality indicators for narrowing the gap of quality of care of breast cancer

    There are differences in the quality of care among breast cancer patients. Narrowing the quality differences could be achieved by increasing the utilization rate of indicators. Here we explored key indicators ...

    Chao Wang, ** Li, Shaofei Su, **nyu Wang, **gkun Li, **aoqiang Bao in BMC Cancer (2019)

  14. Article

    Open Access

    Prognostic value of performance status in metastatic renal cell carcinoma patients receiving tyrosine kinase inhibitors: a systematic review and meta-analysis

    The association between performance status (PS) and the prognosis of metastatic renal cell carcinoma (mRCC) patients receiving tyrosine kinase inhibitors (TKIs) remains controversial. The aim of this study is ...

    Yawei Xu, Yuanyuan Zhang, **anhao Wang, Jiaqi Kang, **aoqiang Liu in BMC Cancer (2019)

  15. Article

    Open Access

    Expression of methionine adenosyltransferase 2A in renal cell carcinomas and potential mechanism for kidney carcinogenesis

    Methionine adenosyltransferase 2A (MAT2A) is an enzyme that catalyzes the formation of S-adenosylmethionine (SAMe) by joining methionine and ATP. SAMe is a methyl donor for transmethylation and has an importan...

    Xuliang Wang, **aoqiang Guo, Wenshui Yu, Cailing Li, Yaoting Gui, Zhiming Cai in BMC Cancer (2014)

  16. Article

    Open Access

    A retrospective study of prostate cancer cases mimicking urothelial cell carcinoma of the bladder

    Prostate cancer (PCa) originating from the prostate base may intrude into the urinary bladder and may be misdiagnosed as bladder cancer. In this retrospective study, we reviewed the clinic data on PCa cases wh...

    Ranlu Liu, **aoqiang **e, Zhihong Zhang, Yong Xu in European Journal of Medical Research (2013)

  17. Article

    Open Access

    Expression and significance of histone H3K27 demethylases in renal cell carcinoma

    The histone H3K27 demethylases UTX and JMJD3 are important regulatory factors that modulate gene expression by altering the physical state of chromatin. Previous studies have indicated an abnormal H3K27 methyl...

    Yongqing Shen, **aoqiang Guo, Yuejia Wang, Wei Qiu, Yanzhong Chang in BMC Cancer (2012)