3 Result(s)
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**aoming Jia
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessGenome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials
While the genetics of MS risk susceptibility are well-described, and recent progress has been made on the genetics of disease severity, the genetics of disease progression remain elusive. We therefore investig...
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Article
Open AccessMulti-arm U-Net with dense input and skip connectivity for T2 lesion segmentation in clinical trials of multiple sclerosis
T2 lesion quantification plays a crucial role in monitoring disease progression and evaluating treatment response in multiple sclerosis (MS). We developed a 3D, multi-arm U-Net for T2 lesion segmentation, whic...
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Article
Open AccessAccurate imputation of human leukocyte antigens with CookHLA
The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an ...
