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Bayesian evolutionary analysis for emerging infectious disease: an exemplified application for H7N9 avian influenza viruses
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Open AccessSudden emergence of human infections with H7N9 avian influenza A virus in Hubei province, central China
There have been five waves of H7N9 avian influenza virus (AIV) infection in humans since its initial emergence in China in 2013, posing a significant threat to public health. Hubei province was free local tran...
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Open AccessPublisher Correction: Sudden emergence of human infections with H7N9 avian influenza A virus in Hubei province, central China
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Why were so few people infected with H7N9 influenza A viruses in China from late 2017 to 2018?
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Open AccessCo-circulation of multiple reassortant H6 subtype avian influenza viruses in wild birds in eastern China, 2016–2017
H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild bir...
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Genetic Variation of Multiple Serotypes of Enteroviruses Associated with Hand, Foot and Mouth Disease in Southern China
Enteroviruses (EVs) species A are a major public health issue in the Asia–Pacific region and cause frequent epidemics of hand, foot and mouth disease (HFMD) in China. Mild infections are common in children; ho...
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Human Endogenous Retroviruses as Biomedicine Markers
Human endogenous retroviruses (HERVs) were formed via ancient integration of exogenous retroviruses into the human genome and are considered to be viral “fossils”. The human genome is embedded with a considera...
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Viromes in marine ecosystems reveal remarkable invertebrate RNA virus diversity
Little is known about ocean viromes and the ecological drivers of the evolution of aquatic RNA viruses. This study employed a meta-transcriptomic approach to characterize the viromes of 58 marine invertebrate ...
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Open AccessA novel tRNA-derived fragment tRF-3022b modulates cell apoptosis and M2 macrophage polarization via binding to cytokines in colorectal cancer
tRNA-derived fragments (tRFs) are a class of small RNAs that occur when tRNAs are broken down by enzymes due to stress. Increasing reports have shown that tRFs are associated with multiple physiological and pa...
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Open AccessResurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong
Hong Kong experienced a surge of Omicron BA.2 infections in early 2022, resulting in one of the highest per-capita death rates of COVID-19. The outbreak occurred in a dense population with low immunity towards...
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The episodic resurgence of highly pathogenic avian influenza H5 virus
Highly pathogenic avian influenza (HPAI) H5N1 activity has intensified globally since 2021, increasingly causing mass mortality in wild birds and poultry and incidental infections in mammals1–3. However, the ecol...
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Open AccessmsBERT-Promoter: a multi-scale ensemble predictor based on BERT pre-trained model for the two-stage prediction of DNA promoters and their strengths
A promoter is a specific sequence in DNA that has transcriptional regulatory functions, playing a role in initiating gene expression. Identifying promoters and their strengths can provide valuable information ...
