Skip to main content

and
  1. No Access

    Article

    Carnosic acid nanocluster-based framework combined with PD-1 inhibitors impeded tumorigenesis and enhanced immunotherapy in hepatocellular carcinoma

    Clinically, the immune checkpoint inhibitor anti-PD-1 antibody has shown a certain effect in the treatment of hepatocellular carcinoma (HCC), which is limited to a small number of patients with HCC. This study...

    Wenhua Wu, Ya** Li, **aokang Wu, Junrong Liang in Functional & Integrative Genomics (2024)

  2. Article

    Open Access

    Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization

    The tumor vasculature was different from the normal vasculature in both function and morphology, which caused hypoxia in the tumor microenvironment (TME). Previous anti-angiogenesis therapy had led to a modest...

    Yang Li, Lei Fu, Baokang Wu, **ngqi Guo, Yu Shi, Chao Lv in Cancer Cell International (2023)

  3. No Access

    Article

    CRISPR–dCas12a-mediated genetic circuit cascades for multiplexed pathway optimization

    The production efficiency of microbial cell factories is sometimes limited by the lack of effective methods to regulate multiple targets in a coordinated manner. Here taking the biosynthesis of glucosamine-6-p...

    Yaokang Wu, Yang Li, Ke **, Linpei Zhang, Jianghua Li in Nature Chemical Biology (2023)