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Open AccessApplication of Lineage Tracing in Central Nervous System Development and Regeneration
The central nervous system (CNS) is a complicated neural network. The origin and evolution of functional neurons and glia cells remain unclear, as do the cellular alterations that occur during the course of ce...
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Article
ASO Author Reflections: Large Language Models Offer Substantial Potential for Specialized Applications in the Medical Field
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Enhanced Artificial Intelligence Strategies in Renal Oncology: Iterative Optimization and Comparative Analysis of GPT 3.5 Versus 4.0
The rise of artificial intelligence (AI) in medicine has revealed the potential of ChatGPT as a pivotal tool in medical diagnosis and treatment. This study assesses the efficacy of ChatGPT versions 3.5 and 4.0...
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Article
Open AccessGenomic epidemiology of CVA10 in Guangdong, China, 2013–2021
Hand, Foot and Mouth Disease (HFMD) is a highly contagious viral illness primarily affecting children globally. A significant epidemiological transition has been noted in mainland China, characterized by a sub...
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Article
Open AccessRole of gut microbiota in doxorubicin-induced cardiotoxicity: from pathogenesis to related interventions
Doxorubicin (DOX) is a broad-spectrum and highly efficient anticancer agent, but its clinical implication is limited by lethal cardiotoxicity. Growing evidences have shown that alterations in intestinal microb...
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Article
Open AccessMiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway
Micro RNAs (miRs) have been implicated in various tumorigenic processes. Osteosarcoma (OS) is a primary bone malignancy seen in adolescents. However, the mechanism of miRs in OS has not been fully demonstrated...
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Article
Open AccessAuthor Correction: YOLOX target detection model can identify and classify several types of tea buds with similar characteristics
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Open AccessYOLOX target detection model can identify and classify several types of tea buds with similar characteristics
Currently, the accuracy of tea bud identification is crucial in the intelligent development of the tea industry, and this is due to the fact that identifying tea buds is a key step in determining the quality o...
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Article
Open AccessSublimed C60 for efficient and repeatable perovskite-based solar cells
Thermally evaporated C60 is a near-ubiquitous electron transport layer in state-of-the-art p–i–n perovskite-based solar cells. As perovskite photovoltaic technologies are moving toward industrialization, batch-to...
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Article
Open AccessEfficacy and safety of corticosteroids, hyaluronic acid, and PRP and combination therapy for knee osteoarthritis: a systematic review and network meta-analysis
There are many injectable treatments for knee osteoarthritis with different characteristics and effects, the aim is to understand which one can lead to better and safer results.
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Article
Design, synthesis and mechanism study of novel natural-derived isoquinoline derivatives as antifungal agents
In screening for natural fungicidal leads, two series of novel 3-aryl-isoquinoline derivatives 8 and 9 were designed and synthesized based on sanguinarine, chelerythrine and berberine. Their structures were confi...
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Article
Open AccessEnzymatic polymerization of enantiomeric L−3,4-dihydroxyphenylalanine into films with enhanced rigidity and stability
L−3,4-dihydroxyphenylalanine is an important molecule in the adhesion of mussels, and as an oxidative precursor of natural melanin, it plays an important role in living system. Here, we investigate the effect o.....
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Open AccessCorrection: Gut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling
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Open AccessGut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling
The intestinal epithelial barrier confers protection against the intestinal invasion by pathogens and exposure to food antigens and toxins. Growing studies have linked the gut microbiota to the intestinal epit...
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Article
Progress in the Research of Wave Slamming Forces on Vertical Cylinders
Wave slamming is an important phenomenon due to its destructive power, and with the rapid development of offshore wind turbines, wave slamming on vertical cylinders has garnered lots of attention. However, the...
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Open AccessCore-predominant gut fungus Kazachstania slooffiae promotes intestinal epithelial glycolysis via lysine desuccinylation in pigs
Gut fungi are increasingly recognized as important contributors to host physiology, although most studies have focused on gut bacteria. Post-translational modifications (PTMs) of proteins play vital roles in c...
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Article
Intelligent identification for vertical track irregularity based on multi-level evidential reasoning rule model
Vertical track irregularity is one of the most significant indicators to evaluate track health. Accurate identification of vertical track irregularity is beneficial to achieve precise maintenance of the track ...
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Article
Blockchain-based mutual authentication protocol without CA
Nowadays, most of the federation chain identity authentication adopts the certificate authentication of CA (Certification Authority) under PKI (Public Key Infrastructure) system, but the authentication of CA i...
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Article
Open AccessEnhanced electromagnetic wave absorption of engineered epoxy nanocomposites with the assistance of polyaniline fillers
In this work, the engineered polyaniline (PANI)/epoxy composites reinforced with PANI-M (physical mixture of PANI spheres and fibers) exhibit significantly enhanced electromagnetic wave absorption performance ...
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Article
Silicon-based nanoprobes cross the blood—brain barrier for photothermal therapy of glioblastoma
Traditional photothermal agents of indocyanine green (ICG) have poor stability, short circulation time, and poor brain permeability due to the blood—brain barrier (BBB), greatly impairing their therapeutic eff...
