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Article
The effect of metformin combined with liraglutide on gut microbiota of Chinese patients with type 2 diabetes
Metformin (MET) is a first-line therapy for type-2 diabetes mellitus (T2DM). Liraglutide (LRG) is a glucagon-like peptide-1 receptor agonist used as a second-line therapy in combination with MET.
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Article
The correlation between circulating growth differentiation factor 11 and the risk of osteopenia/osteoporosis in men
Our results suggest that the serum GDF11 concentration is significantly associated with the risk of bone metabolism dysfunction in men and may be a useful target for prediction of osteopenia/osteoporosis to en...
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Article
Vertical variations and composition of dissolved free amino acid in the seawater of the Yap Trench in the western Pacific Ocean
The composition and concentration of dissolved free amino acid (DFAA) of seawater samples collected in May 2016 from the surface to the hadal zone of the northern region of the Yap Trench were analyzed by pre-...
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Article
Failure Analysis of Sandstone with Filled and Unfilled Cross-Flaws under Uniaxial Compression
The failure characteristics of rock with filled or unfilled cross-flaws are crucial for studying the reinforcement mechanism of grouting. In this study, mechanical tests, digital image correlation and acoustic...
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Article
Numerical investigation on mechanism and fluid flow behavior of goaf water inrush: a case study of Dongyu coal mine
Goaf water inrush has become one of the most prominent issues threatening the safety production of coal mines. To better understand how this hazard develops, a mechanical model and a nonlinear flow model were ...
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Article
Open AccessGenetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells
In response to UV irradiation, translesion DNA synthesis (TLS) utilizes specialized DNA polymerases to bypass replication-blocking lesions. In a well-established polymerase switch model, Polη is thought to be ...
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Article
Plasma periostin as a biomarker of osteoporosis in postmenopausal women with type 2 diabetes
Periostin, as an emerging biomarker, is involved in multiple steps in bone metabolism. This study aimed to investigate the correlation between periostin levels and bone mineral density as well as bone turnover...
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Article
Vertical variations of dissolved carbohydrates in the North Yap Trench
The concentrations of dissolved monosaccharides (MCHO), polysaccharides (PCHO), and total carbohydrates (TCHO) in the seawater samples collected from the north of the Yap Trench in the western Pacific Ocean we...
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Article
Geochemical characteristics of hadal sediment in the northern Yap Trench
Two sediment cores were retrieved in the hadal zone of the Yap Trench, and their concentrations of six major elements Mg, Al, Ca, Ti, Mn and Fe and nine trace elements Sr, Ba, Pb, V, Cr, Co, Ni, Cu and Zn were...
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Article
What sleep behaviors are associated with bruxism in children? A systematic review and meta-analysis
The aim of this article was to assess the sleep behaviors that serve as risk factors related to bruxism in children ages 0 to 12 years by performing a systematic review and meta-analysis of published studies.
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Article
On Traceable Line Graphs
Let G be a simple graph of order n and D 1(G) be the set of vertices of degree 1 in G. In this paper, we prove that if G − D 1(G) is 2-edge-connected and if for every edge ...
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Article
On Hamiltonicity of 3-Connected Claw-Free Graphs
Lai, Shao and Zhan (J Graph Theory 48:142–146, 2005) showed that every 3-connected N 2-locally connected claw-free graph is Hamiltonian. In this paper, we generalize this result and show that ever...
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Article
Open AccessQuantitative LC-MS/MS analysis of seven ginsenosides and three aconitumalkaloids in Shen-Fu decoction
Shen-Fu decoction is a traditional Chinese medicine prescription with a 3:2 ratio of Radix Ginseng and Fuzi ( Radix Aconiti lateralis praeparata ). Ginsenosides and alkaloids are considered to be the main active ...
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Article
Spanning Eulerian Subgraphs of 2-Edge-Connected Graphs
For integers l and k with l > 0 and k > 0, let \({{\fancyscript{C}}(l, k)}\) denote the family of 2-edge-connected gr...