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Article
Intelligent Assist Office Blood Pressures (IOBP) versus awake ambulatory monitoring and conventional auscultatory office readings in Chinese primary medical institutions
To practice standardized office blood pressure (OBP) measurement guidelines pragmatically, we developed an intelligent assisted OBP (IOBP) measurement system in the Chinese community, which can automatically o...
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Article
Interphase heat transfer in radiatively heated particle-laden turbulent channel flows
We investigated the interphase heat transfer characteristics in vertical turbulent channel flows laden with radiatively heated inertial particles considering the gravity of particles. Direct numerical simulati...
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Chapter
Preface: Why China, Engineering, and Ethics?
In the last forty years, China has developed more and more quickly than any other country, society, and (some would even claim) civilization in the history of the world (Kissinger, On China, Penguin Books, 2012).
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Chapter and Conference Paper
Design of Multi-task Scene Image Acquisition System in a Spacecraft Based on TRIZ
Theory of inventive problem solving (TRIZ) is an innovative theoretical system that includes identifying and analyzing technical problems, and obtaining innovative solutions and algorithms for technical proble...
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Chapter
Engineering Ethics Education in China I: History, Policies, and Resources
This chapter provides an overview of the trajectories, resources, and practices of engineering ethics education in China. We begin by recounting the historical background of engineering ethics in China, situat...
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Book
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Article
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing
Alpha-calcitonin gene-related peptide (αCGRP) and substance P (SP) are functionally correlated sensory neuropeptides deeply involved in bone homeostasis. However, they are usually studied individually rather t...
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Article
Intravascular ultrasound provides additional insights in the hypertensive patients with focal renal artery fibromuscular dysplasia
To date, few study has defined the exact role or utility of intravascular ultrasound (IVUS) in the diagnosis and treatment of renal artery fibromuscular dysplasia (FMD). We investigated whether using an IVUS w...
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Article
Interface microstructure regulation and bonding performance of powder metallurgy Al/Mg bimetal with Ni interlayer
Due to its excellent performance of lightweight and high strength, Al/Mg bimetal has high application value in the aerospace field. However, the poor bonding quality of the Al/Mg bimetallic interface is still ...
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Article
Using ultrasound radiomics analysis to diagnose cervical lymph node metastasis in patients with nasopharyngeal carcinoma
This study aimed to explore the clinical value of ultrasound radiomics analysis in the diagnosis of cervical lymph node metastasis (CLNM) in patients with nasopharyngeal carcinoma (NPC).
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Article
SlCK2α as a novel substrate for CRL4 E3 ligase regulates fruit size through maintenance of cell division homeostasis in tomato
This study unravels a novel regulatory module (CRL4-CK2α-CDK2) involving fruit size control by mediating cell division homeostasis (SlCK2α and SlCDK2) in tomato.
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Article
Open AccessStabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML
Cytarabine (Ara-C) is the first-line drug for the treatment of acute myelogenous leukemia (AML). However, resistance eventually develops, decreasing the efficacy of Ara-C in AML patients. The expression of SAM...
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Article
Develo** an Online Data Ethics Module Informed by an Ecology of Data Perspective
A self-perceived lack of training in ethical theories and related pedagogy has kept many engineering faculty members from teaching data ethics, an important aspect of engineering research that has become more ...
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Article
Open AccessThe synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma
Osteosarcoma (OS) is a tumour with a high malignancy level and a poor prognosis. First-line chemotherapy for OS has not been improved for many decades. Bromodomain and extraterminal domain (BET) and histone de...
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Article
Transcriptome analysis of colchicine-induced tetraploid Kiwifruit leaves with increased biomass and cell size
Colchicine-induced polyploidization has been extensively utilized in plant-breeding programs to increase biomass and overall yield of various crop species. Chromosome doubling usually increases the plant size ...
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Article
Diurnal blood pressure pattern and cardiac damage in hypertensive patients with primary aldosteronism
The aim of our study was to evaluate the relationship between the 24-h blood pressure (BP) profile, plasma NT-proBNP levels and left ventricular hypertrophy (LVH) in subjects with primary aldosteronism (PA) co...
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Article
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors
BRAF inhibitors (BRAFi) that target BRAF V600E kinase, a driver mutation found in 50% of melanomas, show a significant antitumor response, but the common emergence of acquired resistance remains a challenge. A...
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Article
MiR-192-5p regulates the proliferation and apoptosis of cholangiocarcinoma cells by activating MEK/ERK pathway
Cholangiocarcinoma (CCA) is the second most common liver cancer, characterized by late diagnosis and fatal outcome. Although miR-192-5p has been shown to have a vital role in various cancers, its role in CCA i...
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Article
Open AccessStrain-activated light-induced halide segregation in mixed-halide perovskite solids
Light-induced halide segregation limits the bandgap tunability of mixed-halide perovskites for tandem photovoltaics. Here we report that light-induced halide segregation is strain-activated in MAPb(I1−xBrx)3 with...
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Article
Development and validation of a clinical and laboratory-based nomogram to predict nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is becoming the leading cause of chronic liver disease in China. The early identification and management of patients at risk are essential. We aimed to develop a novel ...
