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Article
Lactate ameliorates palmitate-induced impairment of differentiative capacity in C2C12 cells through the activation of voltage-gated calcium channels
Palmitic acid (PA), a saturated fatty acid enriched in high-fat diet, has been implicated in the development of skeletal muscle regeneration dysfunction. This study aimed to examine the effects and mechanisms ...
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Article
Tensile Capacity of Self-Piercing Rivet Connections in Thin-Walled Steel and Concrete Composite Structures
In this paper, self-piercing riveting (SPR) is implemented to thin-walled cold-formed steel and concrete (CFSC) composite structures for the first time. Tensile comparison tests were conducted on 5 groups of c...
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Article
Artificial intelligence in liver imaging: methods and applications
Liver disease is regarded as one of the major health threats to humans. Radiographic assessments hold promise in terms of addressing the current demands for precisely diagnosing and treating liver diseases, an...
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Article
Research on Partial Discharge Pattern Recognition in GIS Based on EFPI Sensor
An EFPI fiber optic ultrasonic sensor can be used for the detection and pattern recognition of partial discharge ultrasonic signals in Gas Insulated Switchgear. Compared with traditional piezoelectric sensors,...
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Article
Osteolytic lesion as initial presentation in FIP1L1-PDGFRA-rearranged myeloid/lymphoid neoplasm with eosinophilia: a case report
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Article
Open AccessAlterations in gut microbiota and host transcriptome of patients with coronary artery disease
Coronary artery disease (CAD) is a widespread heart condition caused by atherosclerosis and influences millions of people worldwide. Early detection of CAD is challenging due to the lack of specific biomarkers...
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Article
Development of a highly-efficient erythrocyte-drug covalent conjugation platform and its use in treating thrombotic disorders
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Article
Open AccessOptical blood-brain-tumor barrier modulation expands therapeutic options for glioblastoma treatment
The treatment of glioblastoma has limited clinical progress over the past decade, partly due to the lack of effective drug delivery strategies across the blood-brain-tumor barrier. Moreover, discrepancies betw...
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Article
Inserting EF1α-driven CD7-specific CAR at CD7 locus reduces fratricide and enhances tumor rejection
CAR-T therapies to treat T-cell malignancies face unique hurdles. Normal and malignant T cells usually express the same target for CAR, leading to fratricide. CAR-T cells targeting CD7, which is expressed in v...
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Article
Higher resistance of a microcystin (MC)-producing cyanobacterium, Microcystis, to the submerged macrophyte Myriophyllum spicatum
Outbreaks of Microcystis blooms can affect growth of submerged plants, which in turn can inhibit cyanobacterial growth. Microcystin (MC)-producing and non-MC-producing Microcystis strains typically coexist in Mic...
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Article
Growth and morphological responses of Scenedesmus obliquus to submerged macrophyte Egeria densa
Interspecific interaction are playing vital roles in sha** phytoplankton structure and affecting the food webs in freshwater ecosystems. However, the responses of green algae to allelochemically competition ...
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Article
3D Calculation of MOSFET Junction Temperature Based on the Finite Volume Method
Silicon carbide MOSFET has a wide range of prospective applications in power electronic circuits. The junction temperature is an important indicator of the health of the MOSFET during long-term operation. This...
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Article
Electrospun Porcine Acellular Dermal Matrix and Polycaprolactone Composite Nanofibrous Scaffolds for Accelerating Wound Healing
Electrospun nanofibers represent a novel class of scaffold materials that show great potential in wound healing owing to relatively large surface area, better mimicry of native extracellular matrix, adjustable...
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Article
Multiple habitat templates for phytoplankton indicators within the functional group system
The functional group (FG) system sensu Colin S. Reynolds of freshwater phytoplankton has been widely applied in many aspects of freshwater ecological assessments. However, there is no current consensus as to h...
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Article
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis
The branched-chain aminotransferase isozymes BCAT1 and BCAT2, segregated into distinct subcellular compartments and tissues, initiate the catabolism of branched-chain amino acids (BCAAs). However, whether and ...
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Article
Responses of submerged macrophyte Ceratophyllum demersum to the gradient concentrations of microcystin-LR (MC-LR)
The responses of Ceratophyllum demersum to gradient concentrations (0, 0.8, 3.2, and 10 µg/L) of microcystin-LR (MC-LR) were comprehensively investigated by laboratory simulation experiments. The high reduction a...
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Article
Ecological damage of submerged macrophyte Myriophyllum spicatum by cell extracts from microcystin (MC)- and non-MC-producing cyanobacteria, Microcystis
To explore how decomposed Microcystis-dominant cyanobacterial blooms affect submerged macrophytes, the submerged plant Myriophyllum spicatum was exposed to cell extracts from microcystin (MC)- and non-MC-producin...
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Article
Response of submerged macrophyte Ceratophyllum demersum to the exponential phase (EP) and declining phase (DP) of toxic Microcystis aeruginosa
The present work comprehensively investigated the responses of submerged Ceratophyllum demersum to exudates and extracts of toxic Microcystis aeruginosa at the exponential (EU, ET) or declining phase (DU, DT). Th...
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Article
Open AccessHeparin-induced thrombocytopenia post-cardiovascular interventional therapy: a case report
Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction characterized by thrombocytopenia and thromboembolism. Herein, we present a case of HIT with subcutaneous hemorrhage after c...
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Article
Changes in Global Vegetation Distribution and Carbon Fluxes in Response to Global Warming: Simulated Results from IAP-DGVM in CAS-ESM2
Terrestrial ecosystems are an important part of Earth systems, and they are undergoing remarkable changes in response to global warming. This study investigates the response of the terrestrial vegetation distr...