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    Article

    Integration of single-cell and bulk RNA sequencing revealed immune heterogeneity and its association with disease activity in rheumatoid arthritis patients

    Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disease characterized by cartilage, bone damage, synovial inflammation, hyperplasia, autoantibody production, and systemic features. To...

    **aofan Mao, Maohua Shi, Beiying Zhang, Rongdang Fu, Mengyun Cai in Immunologic Research (2024)

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    Article

    Single-cell and spatial transcriptome analyses revealed cell heterogeneity and immune environment alternations in metastatic axillary lymph nodes in breast cancer

    Tumor heterogeneity plays essential roles in develo** cancer therapies, including therapies for breast cancer (BC). In addition, it is also very important to understand the relationships between tumor microe...

    **aofan Mao, Dan Zhou, Kairong Lin, Beiying Zhang in Cancer Immunology, Immunotherapy (2023)

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    Article

    Evolutionary comparisons of miRNA regulation system in six model organisms

    miRNAs are a class of endogenous small non-coding regulatory RNAs, that can mediate the transcriptional gene silencing as well as gene expression activation. miRNAs, which are found in a wide range of species,...

    **aofan Mao, Li Li, Yicheng Cao in Genetica (2014)