293 Result(s)

Article

Real-World Evidence of FOLFIRI Combined with Anti-Angiogenesis Inhibitors or Anti-EGFR Antibodies for Patients with Early Recurrence Colorectal Cancer After Adjuvant FOLFOX/CAPOX Therapy: A Japanese Claims Database Study

Oxaliplatin-containing adjuvant regimens (folinic acid, fluorouracil, and oxaliplatin/capecitabine and oxaliplatin [FOLFOX/CAPOX]) are used after curative resection of colorectal cancer (CRC). However, real-wo...

Yoshinori Kagawa, Chaochen Wang, Yongzhe Piao, Long **… in Targeted Oncology (2024)

Article

Tumor-associated characteristics and immune dysregulation in nasopharyngeal carcinoma under the regulation of m7G-related tumor microenvironment cells

Nasopharyngeal carcinoma (NPC) is a type of malignant tumor with high morbidity. Aberrant levels of N7-methylguanosine (m7G) are closely associated with tumor progression. However, the characteristics of the t...

Zhen Long, **aochen Li, Wenmin Deng, Yan Tan, Jie Liu in World Journal of Surgical Oncology (2024)

Article

Dietary factors in relation to hypertension: a mendelian randomization study

Observational studies have elucidated the associations between dietary factors and hypertension. Nevertheless, the exploration of these relationships using Mendelian randomization remains scarce currently.

Jiasheng Cai, **aochen Sun, Mingxuan Li… in Journal of Health, Population and Nutrition (2024)

Article

Unraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation

Huanglian Jiedu Decoction (HJD) is a well-known Traditional Chinese Medicine formula that has been used for liver protection in thousands of years. However, the therapeutic effects and mechanisms of HJD in tre...

Yaochen **e, Shuchen Gong, Lingkun Wang… in BMC Complementary Medicine and Therapies (2024)

Article

Identification of an HLA-A*11:01-restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations

Hotspot driver mutations presented by human leukocyte antigens might be recognized by anti-tumor T cells. Based on their advantages of tumor-specificity and immunogenicity, neoantigens derived from hotspot mut...

Meiying Shen, Siyin Chen, **aojian Han, Yanan Hao… in Cancer Immunology, Immunotherapy (2024)

Article

Long-term outcome and fertility results of intraplacental choriocarcinoma: a retrospective study of 14 patients and literature review

Intraplacental choriocarcinoma (IC) is an extremely rare subtype of gestational choriocarcinoma. The long-term follow-up and reproductive outcomes of IC patients remain unclear. Here, we report a series of 14 ...

Yang Liu, **aochen Song, Hui Zhang, Fengzhi Feng… in Orphanet Journal of Rare Diseases (2024)

Article

Meta-analysis on the global prevalence of Arcobacter in food-producing animals and humans

The genus Arcobacter has been associated with illnesses in both animals and humans, where Arcobacter butzleri, Arcobacter cryaerophilus, and Arcobacter skirrowii have been linked to numerous cases of gastrointest...

Penghang Zhang, Yuzhu Liu, Mengjiao Fu, Bing Wang, Shuangyang Ding… in One Health Advances (2024)

Article

Cognitive functions following initiation of antipsychotic medication in adolescents and adults at clinical high risk for psychosis: a naturalistic sub group analysis using the MATRICS consensus cognitive battery

The effects of antipsychotic (AP) medications on cognitive functions in individuals at clinical high-risk (CHR) of psychosis are poorly understood. This study compared the effects of AP treatment on cognitive ...

TianHong Zhang, YanYan Wei, **aoChen Tang… in Child and Adolescent Psychiatry and Mental… (2024)

Article

Clonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer

The increase in the detection rate of synchronous multiple primary lung cancer (MPLC) has posed remarkable clinical challenges due to the limited understanding of its pathogenesis and molecular features. Here,...

Yadong Wang, Zhicheng Huang, Bowen Li, Jianchao Xue… in Cancer Immunology, Immunotherapy (2024)

Article

Retraction Note: Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway

Shengyou Ge, Kexin Wang, Yuxiang Meng, Zongxuan He, **aochen Yang… in Medical Oncology (2024)

Article

Infectious complications in pediatric patients undergoing CD19+CD22+ chimeric antigen receptor T-cell therapy for relapsed/refractory B-lymphoblastic leukemia

Chimeric antigen receptor T-cell (CAR-T) therapy is effective in the treatment of relapsed/refractory acute B-lymphoblastic leukemia (R/R B-ALL); however, patients who receive CAR-T therapy are predisposed to ...

**aochen Wu, Zhanmeng Cao, Zihan Chen, Yi Wang… in Clinical and Experimental Medicine (2024)

Article

The associations of fatty acids related dietary patterns with overweight and obesity among Chinese children

Childhood overweight and obesity is becoming an emerging face of malnutrition. The aims of this study were to develop fatty acid (FAs) related dietary patterns and explored the associations of FAs related diet...

Zhi Huang, Keyu Ma, **aochen Yin, Ziming Li… in Journal of Health, Population and Nutrition (2024)