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  1. Article

    Open Access

    Cryo-EM structure of the ASIC1a–mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect

    Acid-sensing ion channels (ASICs) are neuronal voltage-independent Na+ channels that are activated by extracellular acidification. ASICs play essential roles in a wide range of physiological processes, including ...

    Demeng Sun, You Yu, **aobin Xue, Man Pan, Ming Wen, Siyu Li, Qian Qu in Cell Discovery (2018)