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Article
Open AccessNano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources
At present, heat stress (HS) has become a key factor that impairs broiler breeding industry, which causes growth restriction and poor meat quality of broilers. Selenium (Se) is an excellent antioxidant and pla...
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Article
Open AccessA single-cell transcriptomic study of heterogeneity in human embryonic tanycytes
Disruptions in energy homeostasis can lead to diseases like obesity and diabetes, affecting millions of people each year. Tanycytes, the adult stem cells in the hypothalamus, play crucial roles in assisting hy...
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Article
Hydroxy Selenomethionine Exert Different Protective Effects Against Dietary Oxidative Stress–Induced Inflammatory Responses in Spleen and Thymus of Pigs
Oxidative stress (OS) is widespread in animal husbandry, which causes edema in immune organs and suppresses immune function of animals. Selenium (Se) is an essential trace element involved in immune regulation...
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Article
Immunopeptidome mining reveals a novel ERS-induced target in T1D
Autoreactive CD8+ T cells play a key role in type 1 diabetes (T1D), but the antigen spectrum that activates autoreactive CD8+ T cells remains unclear. Endoplasmic reticulum stress (ERS) has been implicated in β-c...
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Article
Flood hazard assessment in Chenab River basin using hydraulic simulation modeling and remote sensing
This paper analyses flood frequency and performs flood simulation modeling along the Chenab River from Trimmu–Panjnad reach, to simulate flood 2014 and identify resultant flood inundated areas, under different...
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Article
Open AccessDevelopment and verification of a 10K liquid chip for Hainan black goat based on genoty** by pinpoint sequencing of liquid captured targets
China has thousands years of goat breeding and abundant goat genetic resources. Additionally, the Hainan black goat is one of the high-quality local goat breeds in China. In order to conserve the germplasm res...
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Article
Open AccessAn association study of m6A methylation with major depressive disorder
To find the relationship between N6-methyladenosine (m6A) genes and Major Depressive Disorder (MDD).
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Article
The role of exosome derived miRNAs in inter-cell crosstalk among insulin-related organs in type 2 diabetes mellitus
Exosomes are small extracellular vesicles secreted by almost all cell types, and carry diverse cargo including RNA, and other substances. Recent studies have focused exosomal microRNAs (miRNAs) on various huma...
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Article
Codimension-one bifurcation analysis and chaos control in a discrete pro- and anti-tumor macrophages model
The study of genetically engineered macrophages killing tumor cells has become the most promising new direction of cancer therapy. In this paper, we consider discrete macrophages, which are divided into M1 and...
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Article
Open AccessReliability and validity of a graphical computerized adaptive test Longshi scale for rapid assessment of activities of daily living in stroke survivors
Stroke survivors frequently experience difficulties in daily activities, such as bathing, feeding, and mobility. This study aimed to evaluate the reliability and validity of a computer-adaptive test-Longshi sc...
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Article
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids
Autism spectrum disorder (ASD) is a major neurodevelopmental disorder affecting 1 in 36 children in the United States. While neurons have been the focus of understanding ASD, an altered neuro-immune response i...
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Article
Open AccessEffectiveness of azvudine in reducing mortality of COVID-19 patients: a systematic review and meta-analysis
Azvudine has been approved for the treatment of coronavirus disease 2019 (COVID-19) patients in China, and this meta-analysis aims to illustrate the safety of azvudine and its effectiveness in reducing mortality.
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Article
Open AccessFrequency specific alterations of the degree centrality in patients with acute basal ganglia ischemic stroke: a resting-state fMRI study
This study intended to investigate the frequency specific brain oscillation activity in patients with acute basal ganglia ischemic stroke (BGIS) by using the degree centrality (DC) method. A total of 34 acute ...
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Article
Threshold Dynamics and Probability Density Function of a Stochastic Multi-Strain Coinfection Model with Amplification and Vaccination
Multi-strain infectious diseases, which are usually prevented from spreading widely by vaccination, have two main transmission mechanisms: competitive exclusion and co-existence. In this paper, a stochastic mu...
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Article
Open AccessU-shaped association between serum 25-hydroxyvitamin D concentrations and urinary leakage among adult females aged 45 years and over in the United States: a cross-sectional study
The relationship between serum vitamin D status and urinary leakage (UL) among middle-aged females needs to be further studied. The aim of this study was to evaluate the association of serum 25-hydroxyvitamin ...
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Article
Open AccessZinc glycine chelate ameliorates DSS-induced intestinal barrier dysfunction via attenuating TLR4/NF-κB pathway in meat ducks
Zinc glycine chelate (Zn-Gly) has anti-inflammation and growth-promoting properties; however, the mechanism of Zn-Gly contribution to gut barrier function in Cherry Valley ducks during intestinal inflammation ...
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Article
Open AccessThe relationship between academic stress and depression among college students during the COVID-19 pandemic: a cross-sectional study from China
The COVID-19 pandemic is a global public health crisis. During the COVID-19 pandemic, mental health has attracted great attention. However, there is a lack of research on the relationship between academic stre...
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Article
Multiscale information interaction at local frequency band in functional corticomuscular coupling
The multiscale information interaction between the cortex and the corresponding muscles is of great significance for understanding the functional corticomuscular coupling (FCMC) in the sensory-motor systems. T...
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Article
Recent Progress of Surface Plasmon–Enhanced Light Trap** in GaAs Thin-Film Solar Cells
Light trap** technology is one of the effective ways to improve the performance of solar cells, which can enhance the light absorption and reduce the thickness of the material and thus the expense. In recent...
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Article
Non-pharmacological and drug treatment of autonomic dysfunction in multiple system atrophy: current status and future directions
Multiple system atrophy (MSA) is a sporadic, fatal, and rapidly progressive neurodegenerative disease of unknown etiology that is clinically characterized by autonomic failure, parkinsonism, cerebellar ataxia,...
