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Article
Open AccessThe novel circCLK3/miR-320a/FoxM1 axis promotes cervical cancer progression
As a new class of non-coding RNA, circular RNAs (circRNAs) play crucial roles in the development and progression of various cancers. However, the detailed functions of circRNAs in cervical cancer have seldom b...
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Article
Open AccessAblation of LMO4 in glutamatergic neurons impairs leptin control of fat metabolism
The LIM domain only 4 (LMO4) protein is expressed in the hypothalamus, but its function there is not known. Using mice with LMO4 ablated in postnatal glutamatergic neurons, including most neurons of the parave...
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Article
Structural insight into substrate specificity of human intestinal maltase-glucoamylase
Human maltase-glucoamylase (MGAM) hydrolyzes linear alpha-1,4-linked oligosaccharide substrates, playing a crucial role in the production of glucose in the human lumen and acting as an efficient drug target fo...