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3,264 Result(s)
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Article
Stress–Strain Characteristics of Intergranular Liquid Film in High-Silicon Aluminum Alloys
The structure of “Si-liquid film-Si” was constructed by simulating the semi-solid structure of high-silicon Al alloys, and the effects of temperature and thickness on the stress–strain characteristics of Al–Si...
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Article
Expression of Concern to: RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial–mesenchymal transition
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Article
Open AccessIntratumoral microbiome of adenoid cystic carcinomas and comparison with other head and neck cancers
Adenoid cystic carcinoma (ACC) is a rare, usually slow-growing yet aggressive head and neck malignancy. Despite its clinical significance, our understanding of the cellular evolution and microenvironment in AC...
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Article
Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission
Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully understood. Mitochondria, which play a crucial role in energy met...
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Assessment of loss of life caused by dam failure based on fuzzy theory and hybrid random forest model
Dam failure may lead to significant casualties among downstream residents. Therefore, it is crucial to study a reliable method to quantitatively assess the loss of life (LOL) caused by dam failure for emergency r...
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Open AccessLateral root enriched Massilia associated with plant flowering in maize
Beneficial associations between plants and soil microorganisms are critical for crop fitness and resilience. However, it remains obscure how microorganisms are assembled across different root compartments and ...
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Article
Open AccessDeath associated protein like 1 acts as a novel tumor suppressor in melanoma by increasing the stability of P21 protein
Melanoma is a primary malignant tumor with high lethality, which occurs in the skin and eye tissues, while the molecular mechanisms of melanomagenesis remain largely unknown. Here, we show that death-associate...
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Open AccessNew advances in drug development for metabolic dysfunction-associated diseases and alcohol-associated liver disease
Metabolic disorders are currently threatening public health worldwide. Discovering new targets and develo** promising drugs will reduce the global metabolic-related disease burden. Metabolic disorders primar...
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Open AccessHigh-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation
This research aimed to explore whether high-intensity focused ultrasound (HIFU) could conduct pulmonary artery denervation (PADN). HIFU was performed in pulmonary arteries of 6 normotensive rabbits at dose of ...
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Article
Open AccessA novel approach to terminate roof-dependent atrial flutter with epicardial conduction through septopulmonary bundle
Atrial flutter, a prevalent cardiac arrhythmia, is primarily characterized by reentrant circuits in the right atrium. However, atypical forms of atrial flutter present distinct challenges in terms of diagnosis...
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Article
Stress corrosion cracking behavior and mechanism of high manganese steel in inshore SO2-polluted marine environment
High manganese steel (HMS), widely utilized in railway transportation, often encounters the compounded challenge of high stress impact and corrosion, ultimately leading to environmentally assisted cracking. To...
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Open AccessAn novel effective and safe model for the diagnosis of nonalcoholic fatty liver disease in China: gene excavations, clinical validations, and mechanism elucidation
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. NAFLD leads to liver fibrosis and hepatocellular carcinoma, and it also has systemic effects associated with metaboli...
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Targeting specific DNA G-quadruplexes with CRISPR-guided G-quadruplex-binding proteins and ligands
Despite the demonstrated importance of DNA G-quadruplexes (G4s) in health and disease, technologies to readily manipulate specific G4 folding for functional analysis and therapeutic purposes are lacking. Here ...
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Article
Enhancing forest insect outbreak detection by integrating tree-ring and climate variables
Annual tree rings are widely recognized as valuable tools for quantifying and reconstructing historical forest disturbances. However, the influence of climate can complicate the detection of disturbance signal...
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Article
Large porewater exchange reshapes saltmarsh carbon and greenhouse gas budgets on local and global scales
Saltmarshes are carbon-rich ecosystems that play a role in climate regulation by efficiently sequestrating atmospheric CO2. Climate change is a major threat to saltmarshes and will impact saltmarsh carbon sequest...
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Article
Develo** an atmospheric aging evaluation model of acrylic coatings: A semi-supervised machine learning algorithm
To study the atmospheric aging of acrylic coatings, a two-year aging exposure experiment was conducted in 13 representative climatic environments in China. An atmospheric aging evaluation model of acrylic coat...
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Article
Construction of a novel heterostructure of Bi2S3/Sb2S3 nanorod with improved sodium storage performances
In this study, a rod-like heterogeneous Bi2S3/Sb2S3 was systematically engineered through a simple one-step hydrothermal method and subsequently used as an anode active material for sodium-ion batteries (SIBs). T...
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Article
A pth-order random coefficients mixed binomial autoregressive process with explanatory variables
To capture the higher-order autocorrelation structure for finite-range integer-valued time series of counts, and to consider the driving effect of covariates on the underlying process, this paper introduces a pth...
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Article
Relationship between microbial protein and amino acid metabolism in fermented grains of long fermentation period strong-flavor Baijiu
The long fermentation period constitutes a crucial process for enhancing the quality of base liquor in the production of Chinese strong-flavor Baijiu. In the present study, a comprehensive metaproteomic analys...
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Article
Clarify the forming mechanism and affecting factors of defects in semi-stationary shoulder bobbin tool friction stir welding
Different defects of the upper stationary shoulder bobbin tool friction stir welding (SSUBTFSW) were identified in this study, and the Coupled Eulerian–Lagrangian model of SSUBTFSW was used to illustrate the form...