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Article
Open AccessStability and integrity of self-assembled bovine parvovirus virus‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment
Bovine parvovirus (BPV) is an autonomous DNA virus with a smaller molecular size and subtle differences in its structural proteins, unlike other animal parvoviruses. More importantly, this virus has the potent...
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Article
Constructing oxygen deficiency-rich V2O3@PEDOT cathode for high-performance aqueous zinc-ion batteries
Aqueous zinc-ion batteries (AZIBs) have attracted widespread attention due to the advantages of high safety and environmental friendliness. Although V2O3 is a promising cathode, the strong electrostatic interacti...
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Article
ZNF689 deficiency promotes intratumor heterogeneity and immunotherapy resistance in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive disease characterized by remarkable intratumor heterogeneity (ITH), which poses therapeutic challenges. However, the clinical relevance and key determinant...
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Article
Open AccessA quality-comprehensive-evaluation-index-based model for evaluating traditional Chinese medicine quality
Evaluating traditional Chinese medicine (TCM) quality is a powerful method to ensure TCM safety. TCM quality evaluation methods primarily include characterization evaluations and separate physical, chemical, a...
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Article
Open AccessCrack mechanism and experimental verification on straightening of AZ31B magnesium alloy plate
When plates with edge cracks in the rolling process is straightened by cyclic tensile and compressive stress, the tip of edge crack always accompanied by stress concentration, which leads to crack propagation....
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Article
Open AccessA SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective agai...
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Article
Open AccessA deterministic and nature-inspired algorithm for the fuzzy multi-objective path optimization problem
Increasing evaluation indexes have been involved in the network modeling, and some parameters cannot be described precisely. Fuzzy set theory becomes a promising mathematical method to characterize such uncert...
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Article
Open AccessMetavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes
The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcri...
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Chapter and Conference Paper
Practice and Understanding of “Secondary-Tertiary Combination” in Reconstructing Underground Development System
During the high water cut and high oil recovery stage for the water flooding method, the characteristics including stability and specificity become prominent for the underground seepage field.
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Article
Growth characteristics of acclimated strain of Chlorella vulgaris under high concentrations of ammonia nitrogen and phosphorus
Treatment and recycling of high concentrations of ammonia nitrogen (NH4+–N) and tatal phosphorus (TP) is a major challenge in today’s wastewater industry, while microalgae not only captures CO2, but also provide ...
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Article
Analytical Modeling of Fluid Sloshing in A 2D Rectangular Container with A Bottom-Mounted T-Shaped Baffle
An analytical procedure is presented to evaluate the fluid sloshing characteristics in a two-dimensional (2D) rectangular container with a bottom-mounted T-shaped baffle. The fluid region is divided into sever...
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Article
Open AccessDevelopmental brain structural atypicalities in autism: a voxel-based morphometry analysis
Structural magnetic resonance imaging (sMRI) studies have shown atypicalities in structural brain changes in individuals with autism spectrum disorder (ASD), while a noticeable discrepancy in their results ind...
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Article
Potential effect of tropical fruits Phyllanthus emblica L. for the prevention and management of type 2 diabetic complications: a systematic review of recent advances
Phyllanthus emblica is a fruit widely consumed in subtropical areas, which is rich in polyphenols and other nutrients. There are increasing evidences that as a daily and nutritious fruit, it may have a positive r...
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Article
Open AccessGemcitabine and APG-1252, a novel small molecule inhibitor of BCL-2/BCL-XL, display a synergistic antitumor effect in nasopharyngeal carcinoma through the JAK-2/STAT3/MCL-1 signaling pathway
Advanced nasopharyngeal carcinoma (NPC) has a poor prognosis, with an unfavorable response to palliative chemotherapy. Unfortunately, there are few effective therapeutic regimens. Therefore, we require novel t...
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Article
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the p...
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Article
Numerical study of nonlinear interactions of bi-chromatic progressive deep-water waves
This paper proposes a 3-D non-hydrostatic free surface flow model with a newly proposed general boundary-fitted grid system to simulate the nonlinear interactions of the bi-chromatic deep-water gravity waves. ...
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Article
Standards of care for Kasabach−Merritt phenomenon in China
Kasabach−Merritt phenomenon (KMP) is a rare disease that is characterized by severe thrombocytopenia and consumptive coagulation dysfunction caused by kaposiform hemangioendothelioma or tufted hemangioma. This...
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Article
A molecular dynamics study of calcium silicate hydrates-aggregate interfacial interactions and influence of moisture
The interface properties between hydrated cement paste (hcp) and aggregates largely determine the various performances of concrete. In this work, molecular dynamics simulations were employed to explore the ato...
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Article
A numerical investigation of interactions between extreme waves and a vertical cylinder
In this paper, the interactions between extreme waves and a vertical cylinder are investigated through a 3-D two-phase flow model. The numerical model is verified and validated by experimental data. Then, two ...
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Article
Comparison of third-generation sequencing approaches to identify viral pathogens under public health emergency conditions
The capability of high-throughput sequencing (HTS) for detection of known and unknown viruses timely makes it a powerful tool for public health emergency response. Third-generation sequencing (TGS) offers adva...
