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Article
Well-Posedness for Path-Distribution Dependent Stochastic Differential Equations with Singular Drifts
Well-posedness is derived for singular path-distribution dependent stochastic differential equations (SDEs) with non-degenerate noise, where the drift is allowed to be singular in the current state, but mainta...
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Article
Clinical characteristics of membranous nephropathy after allogeneic hematopoietic stem cell transplantation: A real-world multicenter study
Membranous nephropathy (MN) is a rare complication that can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT). MN patients may develop nephrotic syndrome or even kidney failure, which ...
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Article
Effect of Artificial Cooling Extrusion on Microstructure and Mechanical Properties of Mg–Zn–Y Alloys
Microstructure and mechanical properties of Mg–Zn–Y alloys with different Zn/Y atomic ratios with or without artificial cooling (AC) extrusion were systematically investigated in this work. The results show th...
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Article
Simplified p-i-n Perovskite Solar Cells with a Multifunctional Polyfullerene Electron Transporter
In prevailing p-i-n perovskite solar cells (PSCs), solution-processible fullerene molecules are widely used as electron-transporting layers (ETLs) but they typically suffer from poor uniformity and undesirable...
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Article
Open AccessN6-methyladenosine modified TGFB2 triggers lipid metabolism reprogramming to confer pancreatic ductal adenocarcinoma gemcitabine resistance
Gemcitabine resistance is a major obstacle to the effectiveness of chemotherapy in pancreatic ductal adenocarcinoma (PDAC). Therefore, new strategies are needed to sensitize cancer cells to gemcitabine. Here, ...
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Article
Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice
Urolithin A (UroA), a dietary phytochemical, is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins (ETs). The efficiency of ETs metabolism to UroA in humans depends on gut microbiot...
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Open AccessSuccessful treatment of retinopathy of prematurity in oculocutaneous albinism with OCA2 variants: a case report and review of literature
Oculocutaneous albinism (OCA) is a group of autosomal recessive hereditary disorders that affect melanin biosynthesis, resulting in abnormalities in hair, skin, and eyes. Retinopathy of prematurity (ROP) is a ...
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Article
Open AccessEffects of native species richness on reproduction of invasive Bidens pilosa vary with nutrient supply
Both increasing native species diversity and reducing nutrient availability can increase the ability of native plant communities to resist alien plant invasions. Furthermore, native species diversity and nutri...
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Article
A prospective study of zanubrutinib, a Bruton tyrosine kinase inhibitor, in relapsed/refractory idiopathic multicentric Castleman disease
Relapsed and refractory (R/R) idiopathic multicentric Castleman disease (iMCD) is a clinical challenge with no standard treatment. In this preliminary clinical trial, we investigated the efficacy and safety pr...
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Article
Heavy ion energy influence on multiple-cell upsets in small sensitive volumes: from standard to high energies
The 28 nm process has a high cost-performance ratio and has gradually become the standard for the field of radiation-hardened devices. However, owing to the minimum physical gate length of only 35 nm, the phys...
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Article
Open AccessStem cell exosome-loaded Gelfoam improves locomotor dysfunction and neuropathic pain in a rat model of spinal cord injury
Spinal cord injury (SCI) is a debilitating illness in humans that causes permanent loss of movement or sensation. To treat SCI, exosomes, with their unique benefits, can circumvent limitations through direct s...
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Article
Open AccessEstablishment of an automatic diagnosis system for corneal endothelium diseases using artificial intelligence
To use artificial intelligence to establish an automatic diagnosis system for corneal endothelium diseases (CEDs).
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Article
Preparation and characteristics of the O3+-ion-implanted and femtosecond laser-ablated waveguide in the high-gain Nd3+-doped laser glass
In the work, the planar and ridge waveguides are fabricated by the combination of ion implantation and femtosecond laser ablation in the high-gain Nd3+-doped laser glass. The species, energy, and dose of ion impl...
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Article
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer
The retinoic acid receptor-related orphan receptor γ (RORγ) is regarded as an attractive therapeutic target for the treatment of prostate cancer. Herein, we report the identification, optimization, and evaluat...
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Article
Strength evolution and deterioration law of cemented gangue backfill body in acid mine water
Cemented gangue backfill technology is an important backfill mining method. However, the acid mine water environment could seriously affect the strength of the cemented gangue backfill body (CGBB). In this stu...
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Article
Social parasitism behavior between two species of edible wasps in China
We reported the social parasitism behavior between Vespula structor and Vl. flaviceps for the first time. These two Vespula species are both popular edible wasps in southwest China. Such a nest with these two mix...
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Article
Open AccessIdentification of immune-associated biomarker for predicting lung adenocarcinoma: bioinformatics analysis and experiment verification of PTK6
Abnormal expression of protein tyrosine kinase 6 (PTK6) has been proven to be involved in the development of gynecological tumors. However, its immune-related carcinogenic mechanism in other tumors remains unc...
